Award Data

Current cervical spine assessment methodologies are focused on subjective measures (i.e. pain reports) and range-of-motion (ROM) measures that only measure maximum head excursion and reach, but not dynamic motion. Due to report bias and existing incentive

Most standard-of-care tools and techniques for evaluating neck disorders are subjective, unreliable, and do not provide actionable information for providers, payers, and organizations to deliver efficient and effective care. This lack of objective neck he

Defense Health Agency (DHA) is seeking a multi-functional diagnostic to determine blood coagulopathy in real time at point-of-care (POC). Blood coagulopathy, resulting in uncontrolled bleeding, is implicated in 80% of operating room deaths and 50% of trau

Flow Pharma, Inc. is a biotechnology company in the San Francisco Bay Area developing fully synthetic cytotoxic T lymphocyte (CTL)stimulating peptide vaccines for Marburg virus. The FlowVax vaccine platform allows us to create dry powder formulations of biodegradablemicrospheres and TLR adjuvants incorporating class I and class II T cell epitopes. FlowVax vaccines can be designed for delivery by i ...

There is an urgent need to bypass or cross the blood brain barrier (BBB) to deliver drugs for TBI treatment. This project aims to develop targted intranasally delivered, magnetically propulsed, and targted nanoparticles for traumatic brain injury (TBI). In Phase I, we will demonstrate the design, fabrication, and in vitro characterization of proposed drug laden magnetic nanoparticles as well as co ...

This proposal is to develop a Handoff Training for Combat Casualty Care (HTC3) Framework.Training is the crux of the handoff problem today. Patient handoffs are a crucial part of casualty care, both in military and civilian environments; and today handoffs are being performed in less than optimal fashion, with ineffective communications accounting for 80% of the handoff errors. Our new HTC3 Framew ...

Triton Systems will develop a novel approach to field-based disease and biochemical diagnostics through innovative use of extremely low cost bioanalytical devices.The proposed platform will provide a low cost, portable, and reliable diagnostic test for on-site use in austere and resource-limited environments.The devices will be highly durable, rugged, and easy to use without user-induced variation ...

This proposal is in response to the Defense Health Agency 2017 Phase I SBIR topic 17B-005.The approach is the use of a membrane oxygen pump using newly developed nano-thickness membranes with all the layers less than 1 micron total.Nanometer thickness membranes enable more oxygen output per surface area at temperatures of 300-600 C than current state-of-the -art 600-800 C membranes that are 50-300 ...

Adverse physiological events (PEs) have plagued warfighters piloting military aircraft, in particular PEs involving hypoxia and cockpit cabin decompression. Though there has been a large variety of research performed in trying to understand the problems and why theyre caused, there are inefficiencies due to the lack of standardized cross-laboratory protocols, procedures, and metrics. To address th ...

There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terriblemorbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditionalvaccines have proven to be a huge contribution to public health, they do have some limitations especially in the cont ...