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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Advanced Quantitative Magnetic Resonance Imaging Phantoms for Nonalcoholic Fatty Liver Disease

    SBC: CALIMETRIX LLC            Topic: NIBIB

    PROJECT SUMMARYThe overall goal of this Phase I proposal is to design and test the feasibility of novel magnetic resonance imaging (MRI) reference standards (“phantoms”) that are urgently needed for comprehensive and standardized quality assurance (QA) of quantitative MRI biomarkers of non-alcoholic fatty liver disease (NAFLD). We propose to develop 1) a quantitative MR elastography (MRE) stif ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Virtual Reality Technologies for Dynamic Balance Rehabilitation in People with Stroke

    SBC: KOBUK TECHNOLOGIES LLC            Topic: NICHD

    PROJECT SUMMARY/ABSTRACT This project aims to quantify and establish elements of immersive virtual reality (VR) software that, when paired with treadmill training, produce balance perturbations that can be scaled to improve dynamic balance and are tolerated by people with stroke. VR continues to be used as an interactive and engaging way for clinicians to interact with patients during physical the ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  3. A Framework for mHealth App Security and Privacy Analysis

    SBC: UBITRIX INTERNATIONAL, INC.            Topic: NLM

    PROJECT SUMMARY/ABSTRACT With the increased use of mobile health (mHealth) apps to improve health outcomes, protecting private health data is becoming increasingly important. These mHealth apps are offered by healthcare providers and used by patients for various reasons such as paying bills, scheduling appointments, sending messages to providers, accessing lab results, and viewing prescriptions an ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Neural organoid models of the immunological microenvironment of glioblastoma for drug discovery applications

    SBC: STEM PHARM, INCORPORATED            Topic: 102

    Project Summary/Abstract Glioblastoma (GBM) is the most prevalent primary brain tumor in adults with extremely poor survival rates and largely unchanged standard of care. While there are many challenges to developing better GBM treatments, one of the major challenges is the immune-suppressive environment commonly found within GBM tumors. This immune-suppressive nature results in a tumor that is no ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Real-time Multimodal Diffuse Reflectance and Polarization Imaging Based Nerve Identification in Surgical Field of View

    SBC: YAYA SCIENTIFIC LLC            Topic: NIBIB

    PROJECT SUMMARY We propose to develop a novel non-contact, label-free multimodality imager that provides real-time intraoperative identification of nerves within the surgical field-of-view to facilitate the prevention of unintended nerve damage (termed iatrogenic nerve injury) during surgical procedures, as they are a major source of postsurgical complications, e.g., chronic pain. In the United St ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Optimizing Small Molecule Mechanomimetics to Treat Age-related Osteoporosis.

    SBC: OAK RIDGE THERAPEUTIC DISCOVERY LLC            Topic: NIA

    Abstract There is an unmet need to develop treatments for senile osteoporosis, a disorder characterized by an age-related reciprocal decrease in osteogenesis and increase in bone marrow fat. Senile osteoporosis resembles disuse osteopenia, suggesting its pathogenesis involves impaired bone mechanosensing. We discovered that the polycystin heterotrimeric complex (1PC1+3PC2) functions as a mechanose ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Developing a selective TRPC3 ion channel inhibitor for epilepsy treatment

    SBC: SEAK Therapeutics, LLC            Topic: 106

    Project SummaryEpilepsy is one of the most common brain disorders. Current drugs have limited efficacy. Identifying new targeted drugs that can be used as safer, more effective therapies is in urgent unmet need. Selective inhibition of the transient receptor potential canonical 3 (TRPC3) emerges as a novel strategy to impede epilepsy. However, the currently best selective TRPC3 inhibitor, Pyr3, ha ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  8. A Rapid Aerodynamic Prediction Tool for Maneuvering Hypersonic Air Vehicles

    SBC: RESEARCH IN FLIGHT LLC            Topic: X22DOTCSO1

    Research in Flight, Utah State University, MIT, and Syracuse University are proposing the development of a unified hypersonic aircraft design tool that integrates the hypersonic flow analysis capabilities of the commercial FlightStream® flow solver with t

    STTR Phase II 2023 Department of DefenseAir Force
  9. Hardware Implementation of Quantum Algorithms

    SBC: STREAMLINE AUTOMATION LLC            Topic: X22DOTCSO1

    Quantum computer technology is critical and strategic to the Air Force. Quantum processor technology based on topological material (TM) qubits is inherently stable and fault-tolerant because it exploits local topological symmetries. TM are a new class of

    STTR Phase II 2023 Department of DefenseAir Force
  10. Lightweight Containment for Next Generation Batteries

    SBC: MACRO INDUSTRIES INC            Topic: X22DOTCSO1

    As part of updating the Minuteman III Intercontinental Ballistic Missile (ICBM) to the Sentinel ICBM, Launch Facilities (LF) and Launch Control Centers (LCC) will need improved flame protection systems. These facilities shall be supported by large Lithium

    STTR Phase II 2023 Department of DefenseAir Force
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