Award Data

The vast majority of injuries in recent military conflicts have been inflicted by improvised explosive devices (IEDs) causing brain, extremities and genital-urinary injuries. Advanced computational models of IED blast physics and human body injury biomech

Timely management and closure of burn wounds are critical for proper emergency care and the assurance of positive outcomes for the warfighter. Current technologies rely on reagents that cannot respond effectively to the different classes of pathogens that

In this Phase I program, Fabrico Technology, Professor Leonid Bunegin of the University of Texas Health Science Center at San Antonio (UTHSC-SA), and Dr. Rocco Armonda, Director, Neuroendovascular Surgery and Neurotrauma, MedStar-Georgetown University Hos

Burkholderia pseudomallei and Burkholderia mallei are highly pathogenic Gram - negative bacteria and the causative agents of melioidosis and glanders, respectively. These infections, which occur in humans and other animals, are endemic is wide regions of the developing world. This Phase II SBIR project will build on the success of our Phase I work, which established methods for generating monoclon ...

Integrated Clinical Environments (ICE) rely heavily on medical devices that need to be protected from security threats without compromising patient health and safety. There is a need to assess clinical workflow configurations in terms of security, usability, and efficiency. Currently, each medical device has its own security controls. Access to multiple devices in the integrated environment requir ...

We propose to take our hearing-test device, which was designed to support research in advancing hearing-conservation programs, and ruggedize it for use in theater. Five key challenges that make the commercial-off-the-shelf OAE systems unsuitable for HCPs, will be overcome. We will: 1) implement next-generation otoacoustic emission tests to enable OAE measurements in noise-damaged ears, 2) add smar ...

KBSI proposes to design and develop a Data Integration and Predictive Analysis System (IPAS) for the prediction of incidents of human infectious diseases. IPAS will utilize innovative collection of data from open data sources, veterinary and medical professionals, and public observations, together with data cleaning, harmonization, spatio-temporal pattern extraction, factor analysis, and predicti ...

Trauma is the leading cause of death in civilian and military environments and acute hemorrhage contributes to a large portion of these fatalities. Recent experience from Iraq and Afghanistan has demonstrated the crucial role of blood products in the care of critically injured soldiers. Unlike plasma and red blood cells, which can be cold stored for longer time periods, platelets can be safely sto ...

About 40% of trauma-related deaths are related to rapid onset of coagulopathy and the vast majority of trauma patients are coagulopathic at the time of death. Lynntech proposes to develop a novel, easy-to-use and cost effective device for simultaneous quantitative real-time detection of multiple proteins involved in the hemostatic mechanism, using human unprocessed whole blood as the input sample. ...

Bioassays employed to evaluate the diverse range of biomarkers associated with organ injury are time-consuming, costly and require multiple instruments/testing formats to reach a diagnosis (i.e. fluorescence-based capture, ELISAs, PCR, etc.). Individually, these platforms are incapable of predicting the onset of irreversible organ tissue injury (e.g. kidney, liver, heart and lung). If a single mul ...