Award Data

This project team is developing a prototype of software for a tablet computer to replace paper tests for teachers to assess the reading fluency of special education students in grade 5 and 6. The technology will provide: scoring and tracking assessments with a stop watch for appropriate timing of questions, upload of data generated from the assessment directly to a database, audio playback capabil ...

The web-based game, Numbershire II, will include modules to support students with or at-risk for disabilities in learning 2nd grade level mathematics, as defined by Common Core State Standards, including fluency with place value ideas, foundations of multiplication, and procedural fluency with multi-digit operations. In the narrative-based game, each student will build and maintain an idyllic Rena ...

There are a significant number of people in the U.S. whose literacy deficits significantly limit opportunities for written self-expression, including individuals with intellectual disabilities. While this population can offer revealing insights given their unique perspectives, self-expression often occurs in the dependent context of transcription by another person, or, perhaps too often, not at al ...

People with intellectual disability depend a great deal on work for their quality of life. Working in community-based jobs can make substantial differences in income, relationships and self-esteem. Technology has improved opportunities for this population to independently express their career interests, but current tools are limited in that they do not support customization to reflect local job an ...

The project goal is to develop and test the feasibility of a self-management system, Goal Guider, consisting of a mobile application and companion web site that allows individuals with intellectual disabilities and autism to effectively manage self-defined goals for everyday living across various personal, educational, and vocational life domains. Users will be able to easily enter goals, work wit ...

DESCRIPTION (provided by applicant): The goal of this project is to synthesize, based on genomic sequence information, a human cytomegalovirus (HCMV) strain with demonstrated ability to establish persistent infection in sero-positive individuals. The resulting synthetic product will form the basis for the development of attenuated HCMV vaccines. Innovative synthetic biology methods will overcome ...

DESCRIPTION (provided by applicant): Invasive candidiasis (IC) is one of the most serious threats to patients in a critical setting. With as many as 60,000 cases per year in the U.S., the total cost associated with IC in the U.S. may be as high as 2-4 billion/year. One of the most critical factors influencing patient outcome is early diagnosis. The goal of this project is a rapi and inexpensive i ...

DESCRIPTION: New therapeutic agents are urgently needed for the treatment of sickle cell disease (SCD), the world's most common genetic disease. Our long-term goal is to develop a drug for use in children that prevents the inexorable progression of SCD. SCD affects approximately 100,000 people in the United States and millions worldwide. It kills more children in Africa than HIV, but while HI ...

DESCRIPTION (provided by applicant): Breast cancer is expected to cause 39,510 deaths of American women in 2012 and 450,000 deaths globally. Once breast cancer has spread, it is essentially incurable. A critical barrier to treating advanced breast cancer is the lack of cancer-specific drugs that are effective in a large percentage of cancer patients and have low toxicity. Sixone Solutions, LLC pro ...

DESCRIPTION (provided by applicant): Nonlinear optical microscopy techniques (such as two-photon florescence) are being used to acquire volumetric (i.e. three dimensional) images that probe several hundred microns into scattering tissue. These techniques are being combined with fast acquisition schemes to allow imaging of live, moving specimens at high NA. This combination allows for high-resoluti ...