Award Data

The company has developed a silk-derived protein (SDP) for use as a novel ophthalmic formulation excipient that will help to treat the ocular injuries and dry eye pathology that affects over 40 million Americans annually and hundreds of millions of people worldwide. The SDP excipient is designed to enhance tear formulation comfort, longevity, and overall ocular health. This proposal builds on the ...

The CONOPS for the Expeditionary Medical Support System (EMEDS) is based on practical effectiveness, speed, and efficiency. Key among the tools required by the Air Mobility Command and the Air Combat Command, which are two of the major commands that are part of the United Air Force is a multi-channel intravenous infusion pump capable of delivering fluids that meets the safe-to-fly criteria for all ...

CMC Pharmaceuticals, Inc. (Cleveland, OH) is proposing developing a stable, combination product of two small molecule drug candidates as a counter measure to chemical warfare nerve agents (NA). The combination product is expected to exploit complementary pharmacological profiles for optimal muscarinic receptor blockade and anticholinergic activity within the peripheral and central nervous system. ...

We propose a novel two-dimensional mass spectrometry (2D-MS) technique based on ion trap arrays to identify illicit and designer drugs. This approach will give an unprecedented multiplex advantage for miniature mass spectrometry, allowing novice field technicians to rapidly identify drugs affecting the central nervous system based on both the m/z ratio and fragmentation pattern of an ion. Towards ...

Highly pathogenic alphaviruses like VEEV/EEV/WWEEV cause encephalitis in humans and equids. These infections are endemic in wide regions of the developing world. Translational research regarding these pathogens is focused on developing new strategies to detect, treat and ideally protect humans and animals from these infections. Gene-encoded antibodies against alphavirus E1/E2 surface proteins will ...

For standoff chemical identification applications, the longwave infrared has several key lines for spectral discrimination. Unfortunately, most hyperspectral systems are quite large and fragile, making them unwieldy. Nanohmics proposes to demonstrate a chip-scale longwave infrared hyperspectral imaging technology. The weight and packaging volume will be dominated by the fore-optics instead of the ...

Most standard-of-care tools and techniques for evaluating neck disorders are subjective, unreliable, and do not provide actionable information for providers, payers, and organizations to deliver efficient and effective care. This lack of objective neck he

Care for the wounded Warfighters in austere and remote settings makes medical knowledge, skills and efficiency of the military medical professional paramount. For wounds that extend deep into internal anatomy, proper visualization of internal anatomy can

The goal of medical simulation-based training such as high-fidelity manikin simulators, part task trainers, and screen-based virtual patients, is to approximate real-life treatment experiences without risk to live patients. While the use of sensors has ma

A proof-of-concept research on Intelligent Patient Platform is proposed with the goal to improve healthcare training experience by adding natural language capability to patient simulators by leveraging the latest artificial intelligent technologies so tha