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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. SBIR Phase I: A Chemoselective Microreactor for Breath Analysis

    SBC: BREATH DIAGNOSTICS INCORPORATED            Topic: BM

    This SBIR phase I project seeks to address the critical need for lung cancer diagnosis at an early stage. North America has the highest age-standardized incidence of lung cancer in the world. An estimated 224,390 new cases of lung cancer will be diagnosed this year and 158,080 deaths are predicted to occur due to lung cancer in 2016. The five-year survival rate for lung cancer patients is much low ...

    SBIR Phase I 2017 National Science Foundation
  2. Vagus Nerve Stimulation Treatment for Asthmatic Bronchoconstriction

    SBC: ROSELLINI SCIENTIFIC, LLC            Topic: NHLBI

    Project Summary The Specific Aim of this proposal is to test the feasibility of using vagus nerve stimulation VNS for treating asthma related airway constriction that is refractory to current treatments There are approximately million people with asthma in the US About percent of these asthma sufferers experience early and late phase severe asthmatic bronchoconstriction that is refract ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Harvesting specific plant metabolites from hairy root cultures using magnetized nanoparticles

    SBC: NAPROGENIX, INC.            Topic: R

    AbstractPlant cell cultures are becoming a commercially valuable source of pharmaceuticalsparticularly those that are too complex for economical chemical synthesisFor example Phyton Biotechin Germanyhas achieved great commercial success by generating taxoids for Paclitaxel production in sterile plant cell bioreactorsHoweverthe efficiency of these systems is limited by the loss in viability of the ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Experimental Gonococcal Vaccine

    SBC: THERAPYX, INC.            Topic: R

    ABSTRACT Genital tract infection with Neisseria gonorrhoeaegonorrheadoes not induce a state of specific protective immunity and it can be acquired repeatedlyDespite public health measuresthe disease persists at an unacceptably high frequencythere is no vaccine against itand resistance even to the latest generations of antibiotics continues to emergeRecent findings have revealed that Ngonorrhoeae s ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Phase II: Feasibility assessment of a novel tool for mosquito vector control: Auto-Dissemination Augmented by Males (ADAM)

    SBC: MosquitoMate, Inc            Topic: R

    Project summary abstractMosquito control remains the primary tool for combating many mosquito vectored diseasessuch as DengueChikungunyaZikaand West Nilebecause no approved vaccinetherapeutant or prophylaxis is currently available for useKey deficiencies of existing vector control methods include resistance to existing insecticides and the inability to find and treat cryptic breeding siteswhich pr ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a microperforated nanocomposite balloon for intravascular anti restenotic drug delivery

    SBC: ROSELLINI SCIENTIFIC, LLC            Topic: NHLBI

    Hemodialysis is the most common treatment for kidney failure requiring the passing of blood out of the body through a filter and back into the body Almost of hemodialysis patients undergo arteriovenous graft procedures involving the insertion of prosthetic shunts i e synthetic tubes between artery and vein particularly in the forearm With the hemodialysis patient population estimated ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. SA FasL engineered human islets as a novel product for the treatment of type diabetes

    SBC: FasCure Therapeutics LLC            Topic: NIDDK

    PROJECT SUMMARY Type diabetes T D is a chronic autoimmune disorder that affects of population worldwide Exogenous insulin treatment is the standard of care for T D but often negatively affects the quality of life and is ineffective in preventing recurrent hyperglycemia episodes and chronic complications Recent studies show that human islet allografts can restore long term normoglycemia ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Delivery of Nanoencapsulated TGFbeta and ATRA for the Treatment of IBD

    SBC: THERAPYX, INC.            Topic: NIAID

    Abstract TGF NanoCapis an oral combination of nanoparticulate transforming growth factor betaTGFand alltrans retinoic acidATRAin pre clinical development for treatment of inflammatory bowel diseaseIBDPhase I studies provided proof of principle for efficacy in a murine modelPhase II work optimized therapeutic protocolconfirmed efficacy in a second modelestablished scale up manufacturing methodscomp ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. AnomLoc: A perfSONAR-based Distributed Network Anomaly Detection and Localization

    SBC: INFOBEYOND TECHNOLOGY LLC            Topic: 01a

    Data-intensive scientific applications incline to high performance computing which is getting more and more widespread in supercomputing centers, research laboratories, and universities. DoE and many organizations need an automatic and adaptive network analysis tool for effective anomaly detection and localization in the high speed network. Currently approaches, Pythia, APD, etc., are unable to pr ...

    SBIR Phase I 2017 Department of Energy
  10. Fabrication of High-quality NaA Zeolite Membranes with a Novel Plate & Frame Configuration for Molecular-scale Mixture Separations

    SBC: NGIMAT, LLC            Topic: 15e

    Bioethanol has come into widespread use as fuel additives worldwide, especially in the U.S. and Brazil, aiming to mitigate CO2 emissions by up to 70% and sustain the carbon-neutral ecosystem. Generally, bioethanol in various fermentation broths has a maximum concentration of 6-8 wt.%. Hence, concentration of bioethanol from dilute streams poses a grand challenge from the standpoint o ...

    SBIR Phase I 2017 Department of Energy
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