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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 11 - 20 of 167781 results
  1. Validation of a Performance Based Measure of Functioning in MCI and Early AD

    SBC: NEUROCOG TRIALS            Topic: NIA

    Project Summary Alzheimer s disease AD is expected to rise in prevalence from to million Americans by leading to of deaths among adults over This epidemic is projected to overwhelm healthcare and economic resources with costs reaching $ billion in the US in and $ trillion by There is no cure for AD and no new drugs have been successful in treating the advance ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Noninvasive urinary monitoring of NASH by activity based nanosensors

    SBC: Glympse Bio, Inc.            Topic: 300

    Project Summary Abstract Nonalcoholic steatohepatitis NASH is dubbed the stealth epidemic and in the U S alone percent of the million people who are estimated to have NASH will progress and develop life threatening conditions including fibrosis cirrhosis hepatocellular carcinoma and liver failure By the year NASH is projected to be the leading indication for liver transplanta ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. MUC assay for the early diagnosis and management of benign and malignant pancreatic diseases

    SBC: Sanguine Diagnostics And Therapeutics, Inc.            Topic: 300

    Abstract The goal of this Fast track application is to develop a non invasive diagnostic test based on MUC and MUC mucins that can serve as an adjunct to cytological analysis of fine needle aspirates FNAs for accurate prediction of malignancy in patients with cystic pancreatic lesions Due to asymptomatic nature and lack of methods for early detection andgt of pancreatic cancer PC p ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Development and validation of a novel D human in vitro model of nonalcoholic steatohepatitis to be used for novel therapeutic screening and research on disease mechanism

    SBC: Organovo, Inc.            Topic: 365

    ABSTRACT Nonalcoholic fatty liver disease NAFLD is a chronic condition that originates as lipid accumulation within hepatocytes steatosis and progresses into nonalcoholic steatohepatitis NASH characterized by lipid accumulation inflammation oxidative stress and fibrosis An estimated million adults across the U S are thought to have NAFLD with up to million more estimated to hav ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. High Density Miniaturized Zero Switching Stimulation and Recording Headstage for Small Animals

    SBC: ADVANCED MEDICAL ELECTRONICS CORPORATION            Topic: 101

    Project Summary Abstract Combining high channel count electrophysiological recording of neural activity with patterned electrical micro stimulation has been severely constrained by technical limitations Foremost among these limitations are the problems associated with simultaneous recording and micro stimulation Stimulation artifacts are up to four orders of magnitude larger than the neural sig ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Development of Novel and Affordable Neoglycosylated Long Acting Superactive Analog of Human FSH for Infertility

    SBC: TROPHOGEN INC            Topic: NICHD

    PROJECT SUMMARY ABSTRACT It is estimated that over of all American couples suffer from infertility a topic of great importance to NICHD and cited frequently by this Institute Professional American women andamp those from all developed nations increasingly delay childbearing for several years compared to the past because of career advancement and increasing social acceptability This problem ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Minimally Invasive Cardiac Sympathetic Denervation for Malignant Ventricular Arrhythmia

    SBC: Coridea, LLC            Topic: NHLBI

    Sympathetic innervation of the heart plays a critical role in arrhythmogenesis and recent studies have highlighted the role of surgical sympathetic denervation in management of refractory ventricular arrhythmias The procedure although safe is very invasive and performed via thoracoscopy using single lung ventilation This is not tolerated by patients with lung disease or severe structural heart d ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. The Bimodal Ankle: Development and Engineering Validation of a Hydraulic Actuator

    SBC: OHIO WILLOW WOOD COMPANY, THE            Topic: n/a

    This project designs, fabricates, and completes engineering verification of a hydraulic actuator for a novel prosthetic ankle-foot system. The goal of this project is to improve balance and balance confidence of persons with lower extremity amputations by developing a prosthetic ankle that has biomimetic modes for walking and standing. This bimodal ankle provides flexibility for walking mobility a ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. Improving Hearing Aid Satisfaction Through Remote Feedback and Settings Adjustments

    SBC: Innovative Design Labs Inc.            Topic: n/a

    This project develops a system that improves communication between a patient and their audiologist, simplify the fitting and tuning process by allowing patients to remotely record their hearing aid (HA) experience via a smartphone application. Currently, only 28.5% of individuals who could benefit from a HA actually wears one. The goal of this project is to improve patient satisfaction with their ...

    SBIR Phase II 2018 Department of Health and Human Services
  10. STTR Phase I: Wireless High Temperature Sensor for Real Time Monitoring of Power Generation Turbine Engines

    SBC: Sensatek Propulsion Technology, Inc.            Topic: MI

    This Small Business Innovation Research Phase I project is for the development of a wireless sensor for continuous and real-time measurement of the high temperature in gas turbines. The new sensor offers turbine manufacturers and owners/operators the capability to place small-sized sensors in hard to reach areas in the turbine, and transmit sensed data wirelessly thereby enabling heat loads to be ...

    STTR Phase I 2018 National Science Foundation

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