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MAPPING AND SEQUENSING THE DNA IN THE HUMAN GENOME IS OF CRUCIAL IMPORTANCE TO FUTURE MEDICAL ADVANCES AND ECONOMIC COMPETITIVENESS. UTILIZATION OF DNA PROBES LABELED WITH DOZENS OF STABLE ISOTOPES INSTEAD OF A SINGLE RADIOISOTOPE COULD INCREASE THE RATE OF SEQUENCE DETERMINATION 100-FOLD OR MORE COMPARED TO CURRENT METHODS. THIS PROJECT INVOLVES A NEW APPROACH, LASER ATOMIZATION RESONANCE IONIZAT ...

AMORPHOUS SILICON (A-SI) THIN FILM PARTICLE DETECTOR, AS AN EMERGING PARTICLE DETECTION DEVICE, WITH EXCELLENT RADIATIONHARDNESS AND LOWER PRODUCTION COST THAN CRYSTALLINE SILICON (C-SI), HAS ATTRACTED MORE ATTENTION AND IS UNDER ACTIVE DEVELOPMENT WITH PROMISING PERFORMANCE IMPROVEMENTS. DEVELOPING THIN FILM TRANSISTORS (TFT) WHICH CAN BE FABRICATED ON THE SAME SUBSTRATE OF A-SI THIN FILM PARTICL ...

NANOMETER-SCALE AGGREGATES OF ORDER 10 TO 100 ATOMS, KNOWN AS CLUSTERS, HAVE GENERATED A GREAT DEAL OF INTEREST IN RECENT YEARS DUE TO THEIR POTENTIAL APPLICATIONS AS CATALYSTS, OPTICAL MATERIALS AND ELECTRONIC MATERIALS. STABLE CLUSTERS OF CARBON HAVE BEEN OBSERVED AND A UNIQUE SPHERICAL STRUCTURE SIMILAR TO THAT OF A SOCCER BALL HAS BEEN PROPOSED FOR THEM. CARBON CLUSTERS ARE GIVEN THE NAME FULL ...

THE USE OF TRACERS TO TAG WELL GAS WHICH IS REINJECTED INTO OIL RESERVOIRS HAS ACHIEVED CONSIDERABLE SUCCESS IN CHARACTERIZING THE STRUCTURE AND GEOMETRY OF THE RESERVOIRS. IDEALLY, THE TRACER SHOULD BE DETECTABLE OVER A WIDE DYNAMIC RANGE, PARTICULARLY IN FIELDS WHERE LARGE VOLUMES OF GAS ARE INJECTED. THE OBJECTIVE OF THE PROPOSED RESEARCH IS TO DEMONSTRATE ORDERS-OF-MAGNITUDE INCREASE IN DYNAMI ...

THIS PROJECT WILL RESULT IN THE DEVELOPMENT OF A NEW TECHNOLOGY FOR MEASURING THE QUANTITY AND LOCATION, WITH SUBMICRON RESOLUTION, OF BORON IN BIOLOGICAL CELLS IN SUPPORT OF THE BORON NEUTRON CAPTURE THERAPY (BNCT) PROGRAM. THIS PROJECT THUS ADDRESSES THE MAJOR UNSOLVED TECHNICAL ISSUE IMPACTING BNCT CLINICAL EFFICACY. BNCT IS APROMISING RADIATION THERAPY IN WHICH NEUTRONS ARE USED TO ACTIVATE BO ...

THIS PROPOSAL DESCRIBES A LIQUID HELIUM PUMP DESIGNED TO MEET REQUIREMENTS FOR LIQUID HELIUM CIRCULATION THROUGH SUPERCONDUCTING SUPER COLLIDER MAGNET STRINGS. THE PUMP IS A FOUR-CHAMBER POSITIVE DISPLACEMENT NUTATING MACHINE WITH LOW NPSH. IT IS CAPABLE OF PRODUCING HIGH HEADS WITH LITTLE IMPACT ON EFFICIENCY FOR TURN DOWN RATIOS AS HIGH AS 5 TO 1. THE FOUR-CHAMBER DESIGN PROVIDES OUTLET FLOW WIT ...

THIS PROJECT WILL EVALUATE THE EFFECT OF ACCELERATORS, FLEXIBILIZERS, AND METALLIC AND NONMETALLIC RESIDUAL ELEMENTS ON THE CRYOGENIC FATIGUE LIFE OF INSULATING MATERIALS USED IN SUPERCONDUCTING MAGNETS. THESE ADDITIVES ALTER THE CHEMICAL STRUCTURE OF EPOXY-RESIN SYSTEMS AND THUSWILL AFFECT THE RESPONSE OF THE MATERIAL TO RADIATION AND LOW TEMPERATURES. AN INTEGRATED, INNOVATIVE PROPRIETARY APPROA ...