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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Safety and Tolerability of TASIS-Peanut (Targeted Allergen Specific Immunotherapy within the Skin) patch for the Treatment of Peanut Allergy

    SBC: MOONLIGHT THERAPEUTICS, INC.            Topic: NIAID

    The following contains proprietary/privileged information that Moonlight Therapeutics requests not be released to persons outside the government, except for purposes of review and evaluation Safety and Tolerability of TASIS-Peanut (Targeted Allergen Specific Immunotherapy within theSkin) patch for the Treatment of Peanut Allergy Food allergies affect 30 million people in the USA and 17 million in ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Developing a Digital Training and Assessment Platform to Disseminate a Successful NIH-Supported College Preparation Model for Diversifying the U.S. Biomedical Workforce

    SBC: MOTHER COMMUNICATIONS CO.            Topic: 500

    Abstract: Developing a Digital Training and Assessment Platform to Disseminate a Successful NIH- Supported College Preparation Model for Diversifying the U.S. Biomedical Workforce This Phase 1 SBIR project will design and test a digital training and assessment platform—HSTA Hatch—to help geographic regions outside West Virginia (WV) establish workforce development programs for grade 9-12 youth ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  3. A Low-Cost Wearable Connected Health Device for Monitoring Environmental Pollution Triggers of Asthma in Communities with Health Disparities

    SBC: WI-SENSE LLC            Topic: NHLBI

    Project Abstract Asthma affects 25 million Americans, and chronic obstructive pulmonary disease (COPD) affects 16 million,together costing 130 billion USD annually to the US healthcare system. Asthma is more prevalent in AfricanAmerican population (10.6%) than white population (7.7%). Poverty level has an impact as well, with twice asmuch asthma incidence in people below 100% of the poverty thresh ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Developing an integrated pipeline for routine generation of orthogonal GPCR-targeting nanobodies

    SBC: VITAN-BIOTECH LLC            Topic: 300

    Project SummaryA broad range of neurological indications, including schizophrenia, pain, Parkinson's and Alzheimer's diseases, and autism have been linked to G-protein coupled receptor proteins (GPCRs), making them attractive targets for therapy. Understanding GPCR dysfunction is essential for effective therapeutic development. However, deciphering the functions of GPCRs remains a daunting task in ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Advanced Pediatric Airway Trainer for Enhanced Clinical Education in Pediatric Critical Care

    SBC: TDA RESEARCH, INC.            Topic: NICHD

    Project Summary/Abstract Clinical training aids such as surgical mannequins and procedural trainers are important tools for teaching proper technique to physicians and first responders. However, the majority of these training tools were developed for adult anatomies. Pediatric patients are often more challenging to treat, but few resources exist for advanced simulation in pediatric critical care e ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Novel drug combinations for improving survival from acute radiation syndrome when administered 48 hours post- irradiation

    SBC: BOLDER BIOTECHNOLOGY INC            Topic: NIAID

    Abstract. Bone marrow is one of the most radiation-sensitive tissues, and patients acutely exposed to total body irradiation (TBI) doses rt 2 Gy develop severe neutropenia, thrombocytopenia, anemia, and lymphopenia within days to weeks of exposure, often dying from infections (due to a lack of neutrophils) and uncontrolled bleeding (insufficient platelets) (referred to as the hematopoietic acute r ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  7. SensiTrak: Automated Assessment of Forelimb Sensation

    SBC: VULINTUS, INC            Topic: NINDS

    Project Abstract Current common methods for measuring somatosensory function in preclinical rodent models generally rely on withdrawal responses to uncomfortable or painful stimuli. These tests can be stressful to the animal, while also yielding a high variability in measured responses, and repetitive testing in longitudinal models may even result in chronic pain states. To better understand the c ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Comparative testing of tatCN19o for neuroprotection in rodent tMCAo

    SBC: NEUREXIS THERAPEUTICS, INC.            Topic: NINDS

    Project Summary/Abstract Focal cerebral ischemia (stroke) afflicts nearly 800,000 Americans each year and often results in permanent cognitive impairment or death. Efforts in developing a cerebroprotective stroke therapy have largely resulted in disappointment: the only approved pharmacological therapy is hemolytic treatment with tissue plasminogen activator (tPA; alteplase). In this project, we w ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Development of an AI-empowered device that utilizes multimodal data-visualization to aid in the diagnosis, and treatment, of OUD

    SBC: WAVi Co.            Topic: NIDA

    Abstract Assessing the effectiveness of opioid use disorder (OUD), where high relapse rates create financial and social tolls, is a pressing clinical problem in need of better measurement tools. The ability to identify cognitive changes should improve outcomes but current intake into rehabilitation programs doesn’t typically include cognitive tests. Simple, quick, cost-effective, and objective m ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  10. Topical Drug Delivery System as an Anti-Inflammatory and Pro-Angiogenic Therapy for Diabetic Wound Healing

    SBC: GELSANA THERAPEUTICS INC            Topic: 200

    SUMMARY Impaired wound healing in diabetic patients represents a major clinical problem, resulting in prolonged hospitalizations and significant healthcare expenditures. The financial burden of this is extreme, representing $78 billion annually in the U.S. alone. Two-thirds of all non-traumatic amputations are preceded by a diabetic wound, and every 20 seconds a lower limb is lost to a diabetic wo ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
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