Award Data

DESCRIPTION (provided by applicant): Doxorubicin (DOX) is an important anticancer drug with a wide array of therapeutic uses. Despite its very frequent clinical use, the utility of DOX is severely compromised by dose-limiting cardiotoxicities. While DOX cardiotoxicity has been known for many years, it remains a contemporary problem and therapies to prevent it have not been optimized. The only cur ...

The Phase II base period research effort will focus on demonstrating the operability of the rechargeable cryogenic liquid oxygen storage and delivery system under a variety of conditions including: start/stop/transient conditions at the maximum and minimumflow rates, and power generation with integrated fuel cell in the 10-100 W range. The Engineering Prototype liquid oxygen storage system will b ...

This STTR proposal addresses the development of novel guided wave devices that use photonic band gap technology in epitaxial thin-film ferroelectric barium titanate. This proposed project combines the advanced ferroelectric materials technology developedat Northwestern University with the photonic integrated circuit expertise of Srico to develop next generation nanophotonic hybrid circuit devices. ...

High current carrying conductors for various commercial and military applications can be fabricated by using a coating of high-temperature superconductor such as Yttrium-Barium-Copper-Oxide (YBCO) on a suitable metallic tape. It has been shown, however,that YBCO films deposited directly on polycrystalline metal substrates exhibit poor superconducting properties at liquid nitrogen temperature. A ...

The development of compact, lightweight and continuous power sources to replace battery-based systems offers substantial advantages for military operations. Fuel cells offer high energy density (up to 1000 Wh/kg) and operate continuously as long as fuelis provided. Advantages of fuel cells include high efficiency and very low release of polluting gases. Current proton exchange fuel cell technol ...