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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Development of mitoNEET agonists for the treatment of stroke
SBC: MODULATION THERAPEUTICS, INC. Topic: 102ABSTRACT Stroke is the fifth leading cause of death and the leading cause of disability in the United StatesThere remains a critical need for innovative therapeutic approaches that can successfully prevent or reverse brain injury following strokeDysfunction of the mitochondrial biochemistry following ischemic stroke and reperfusion injury contributes to significant neuronal cell losshoweverthe dev ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Novel sanitizer/disinfectants against viral infections with long-lasting effect
SBC: CAMELLIX, LLC Topic: NIAIDAbstractNorovirus is the most common cause of acute gastroenteritis in the United States, associated annually with 19-21 million illnesses, 56,000-71,000 hospitalizations and 570-800 deaths (US CDC, Overview about Norovirus). Norovirus is one of the nonenveloped viruses that are resistant to alcohol sanitization. According to US CDC Guidelines for the Prevention and Control of Norovirus Gastroente ...
STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
The Antibody Registry: A Community Authority for Antibody Research Resource Identifiers
SBC: SCICRUNCH Topic: 300Project SummaryOne of the most glaring yet easily addressable gaps in our current scientific workflow and publication system is improving the way that methods are reportedin particularthe lack of key methodological details necessary for interpreting and reproducing a studyMost authors continue to cite the name of the reagentlike an antibody using the vendorand the city where the vendor is locatedb ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Translational development of specialized NK cells for cancer immunotherapy
SBC: Indapta Therapeutic Topic: 102Project Summary Abstract The annual incidence of head and neck cancers worldwide is more thancases with arounddeaths each yearand it is estimated that inthere will benew cases of non Hodgkin lymphoma with an estimateddeaths this yearIn this proposalwe describe a strategy to use a novel subset of natural killer cellsg NK cellsallogeneically for cancer therapyWe hypothesize that expansion and adopti ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
BlueBox: A Complete Code Blue Data Recorder, Phase II
SBC: NeoVative, Inc. Topic: 400“Code blue” is the signal used in hospitals to call for an immediate cardiopulmonary resuscitation (CPR) following a cardiac or respiratory arrest. Reviewing the performance of the “code blue team” is a cornerstone for improving outcomes. The current standard of using handwritten records on a paper “code sheet” does not allow measurement of key quality indicators and is subject to huma ...
STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
AHTP-comet: development of an automated, high throughput comet assay system
SBC: ENGINEERING RESOURCES GROUP INC Topic: NIEHSPROJECT SUMMARY Genomic instabilityinduced by DNA damageand partly mitigated by DNA repair and antioxidantsplays a critical role in the pathogenesis of many major human diseasessuch as neurodegenerationcancer and cardiovascular diseasetogether with agingThere is a critical need for automated assays that can perform these assessmentsand bring them into greater routine usewhich will help advance our ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Mitigation of Radiation Therapy Induced Neuroinflammation and Cognitive Dysfunction
SBC: IMMUNOCHEM THERAPEUTICS LLC Topic: 102PROJECT SUMMARY Cognitive decline and deterioration of long term cognitive performance are major side effects of CNS cancer treatmentBrain metastases are the most common CNS malignancies and a common cause of morbidity and mortality in aboutof all cancer patients with systemic diseaseaffecting overpatients in the US annuallyAs most systemic chemotherapy agents do not cross the blood brain barriert ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Development of a tracheal sound sensor for early detection of hypoventilation due to opioid overdose.
SBC: RTM Vital Signs, LLC Topic: R41Abstract More thanAmericans died from drug overdose inand drug overdose is now the most common cause of death for people underyears old in the United StatesFurthermorethe number of overdose deaths is increasing with the rise of abuse of powerful synthetic opioidssuch as fentanylIn May ofNational Institutes of HealthNIHand National Institute on Drug AbuseNIDAdirectors DrsCollins and Volkow outlined ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Discovering a Small Molecule that Targets the KSHV Processivity Factor for Treating Oral and Systemic Kaposi Sarcoma
SBC: FOX CHASE CHEMICAL DIVERSITY CENTER INC. Topic: NIDCRKaposi SarcomaKSis the most common cancer in themillion worldwide AIDS populationKS tumors are caused by Kaposi Sarcoma Associated Herpes VirusKSHVEven though HAART therapy has resulted in a dramatic decline in KS in the USthis malignancy remains the most predominant tumor of AIDSParadoxicallyKS tumors arise in some AIDS patients following HAART treatmentdue to Immune Reconstitution Inflammatory S ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Developing a Scalable Manufacturing Process for an Oral Bacteriophage Product that Prevents Cholera
SBC: PHAGEPRO, INC. Topic: NIAIDPROJECT SUMMARY Cholera is an acute and severe disease caused by the bacterium Vibrio cholerae that is spread primarily through contaminated water sources due to a lack of adequate sanitation infrastructure. The World Health Organization estimates that there are at least 3 million cases globally per year, 40 percent of which are spread through household transmission. Current prevention methods req ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health