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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A daily client check-in system for outpatient substance abuse treatment
SBC: COG ANALYTICS, LLC Topic: NIDAAbstract Alcohol and illicit drug use remain highly prevalent in the US, and epidemiological surveillance surveys estimate that over 20.6 million individuals (~ 8% of the US population) meet standard diagnostic thresholds for substance use disorders (SAMHSA, 2011). Outpatient substance abuse treatment is the predominate method of treatment in the US for SUDs, typically involving intermittent cont ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Drug Delivery Method for Sudden Sensorineural Hearing Loss
SBC: WEINBERG MEDICAL PHYSICS, INC. Topic: NIDCDDESCRIPTION (provided by applicant): The ultimate goal of the proposed project is to evaluate and commercialize a combination of proprietary magnet assemblies and magnetic nanoparticles (initially developed by our University STTR partner), that has been shown in preliminary animal studies to improve delivery of medications to the inner ear. Initial animal studies using the system (which uses magne ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Novel Pharmacotherapeutic Bioadhesive Patch for Oral Ulcerations
SBC: POST OAK PHARMACEUTICALS, INC. Topic: NIDCRProject Summary Oral ulceration is one of the most commonly encountered oral diseases, with an estimated prevalence of 4% in the USA. Managing large or multiple ulcers that are caused by diseases of unknown etiology, such as erosive lichen planus or aphthous ulcers which affect 25% of the population worldwide, is also a challenge to dentists and specialists. Ulceration of the oral mucosa can caus ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
A New MicroRNA-1291 Replacement Therapy for Pancreatic Cancer Disease
SBC: MIRNA THERAPEUTICS, INC. Topic: NIAAADESCRIPTION (provided by applicant): Pancreatic cancer is the fourth leading cause of cancer-related death in the United States. There is a clear need for more effective therapies to treat deadly pancreatic cancer disease. MicroRNAs (miRNA or miR) are a large group of short, noncoding RNAs that control posttranscriptional gene expression in human cells, and there is increasing evidence for the exi ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
High Throughput Manufacturing of Monodispersed Nanoparticles for Biomedicine
SBC: CHEMTOR, L.P. Topic: NIADESCRIPTION (provided by applicant): This Phase I Small Business Technology Transfer (STTR) project focuses on the development of a new platform manufacturing process for large-scale preparation of monodispersed polymeric nanoparticles (NPs) suitable for biomedical applications through the use of a large-scale fiber fluidic system. Although laboratory processes for reproducible synthesis of polyme ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
A Millimeter-wave Tunable Cavity for Ultra-sensitive Solids and Liquids DNP-NMR at Low Budget
SBC: DOTY SCIENTIFIC, INC. Topic: NIA? DESCRIPTION (provided by applicant): NMR is probably the most powerful and widely used analytical technique for structure determination and function elucidation of molecules of all types, but it suffers from low sensitivity, particularly for insoluble biological macromolecules. Dynamic Nuclear Polarization (DNP) with Magic Angle Spinning (MAS) has recently demonstrated S/N gains exceeding t ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
R3: A Smart Attachment for Improving Adherence and Usage of Metered Dose Inhalers
SBC: Cognita Labs, LLC Topic: NIDADESCRIPTION (provided by applicant): Respiratory illnesses continue to be on the rise1-4, in particular, COPD alone impacts nearly 210 million globally 6. Metered Dose Inhaler (MDI) is the most common mechanism to deliver medicine, and is used by the patients for both maintenance and rescue medications. It is well established that regular use of the medications minimizes long-term damage to the lu ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Effect of VBP15, a dissociative steroidal analogue, on intestinal epithelial repair processes in inflammatory bowel disease
SBC: REVERAGEN BIOPHARMA, INC. Topic: NIDDK? DESCRIPTION (provided by applicant): Glucocorticoids (e.g. prednisolone) are prescribed frequently to treat inflammatory bowel disease (IBD). Despite effectiveness, adverse side effects believed to be caused by GRE-mediated transcriptional propertieslimit long term use of glucocorticoids in IBD patients. Furthermore, these GRE-mediated transcriptional activities have been previously shown to ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
EKO Approach To Find Small Molecules That Perturb Protein Protein Interaction
SBC: Small Molecule PPI Mimics LLC Topic: NIGMSDESCRIPTION (provided by applicant): One of the major new frontiers in the pharmaceutical industry is the design of small molecules to perturb protein-protein interactions PPIs. Many medicinally validated protein targets involve PPIs, but the methods available to discover small molecules that perturb these are, on aggregate, inadequate. Small Molecule PPI Mimics LLC owns intellectual property cove ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Using Structuring Interacting RNAs (sxRNAs) as microRNA Inhibitors
SBC: HocusLocus Inc. Topic: NIGMSDESCRIPTION (provided by applicant): We propose developing a trans-molecular RNA-switch for scientists to negatively affect the activity of endogenous microRNA for use as a molecular tool or therapeutic, an anti-miR. Since the discovery of miRNA, the creation of effective anti-miRs has been important, first to study and verify miRNA interactions, and, secondly, as a therapeutic tool. But, creating ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health