Award Data

PROJECT SUMMARYSubarachnoid hemorrhage (SAH) due to rupture of an intracranial aneurysm leads to delayed vasospasm resulting in neuroischemia (stroke). The overall morbidity (profound neurologic deficit in 10-20% of survivors) and mortality (50%) are high, and the disease affects a relatively young adult population. Therapeutic options to prevent delayed vasospasm and neuroischemia after SAH are c ...

PROJECT SUMMARY We propose to develop a novel contact, label-free multimodality-based sensing probe that provides real-time intraoperative identification of nerves within the thermal damage threshold range of a surgical tool. The tool will facilitate prevention of direct/indirect nerve damage (termed iatrogenic nerve injury) during surgical procedures, as they are a major source of postsurgical co ...

PROJECT SUMMARYMicroprocessor-controlled ankles have been shown to substantially improve mobility and stability in individuals with lower limb amputation, but these devices are typically only available to higher mobility users due to a lack of scientific evidence to justify insurance reimbursement. As such, many of the individuals with lower limb amputation that have the greatest need for advanced ...

PROJECT SUMMARY The American Academy of Dermatology reports that 1 in 4 Americans (~84.5 million) are impacted by skin disease. Skin disease is the fourth leading cause of disability worldwide, significantly impacts quality of life, and costs ~$75 billion annually to treat. Skin conditions like atopic dermatitis (AD) are commonly diagnosed by practitioners using clinical history and physical exam ...

In this effort GTL proposes to develop an additive production system for telescope mirrors leveraging previous research efforts for DARPA, MDA, and NASA. The proposed production method allows for a wider range of substrate materials while allowing for pre

  Whisper Aero proposes investigating a novel electric propulsor designed to achieve ultra low noise, high specific power, and high efficiency both at static and high speed cruise conditions. These capabilities are critical to enable eVTOL aircraft to achieve scaled market use in urban areas, and the wide breadth of mission applications across commercial, public use and military aircraft. The eQ ...

  Whisper Aero proposes building a flexible acoustic framework designed to be user-friendly, that enables engineers to easily connect multi-fidelity aerodynamic tools to multiple acoustic models. Though noise is a significant constraint in military and consumer missions, OEMs are still struggling to design for acoustics due to difficulties connecting multi-fidelity, multiple paradigm aerodynamics ...

Polyimide (PI) is an important engineering polymer with excellent thermomechanical, electrical and chemical resistant properties at high temperatures. However, melt processing of polyimide is difficult. At present, it is limited to filmic structure or compression molding. This proposal posits two concepts to improve melt processibility of PI. From prior research, we demonstrated 1) imidi ...

Homogeneous software applications employed throughout NORTHCOM pose a huge opportunity for adversaries to scale exploits within the defense ecosystem. Unmanned Aerial System (UAS) applications specifically pose a huge attack vector due to the large reliance on open source components containing publicly disclosable vulnerabilities. ARMS is providing solutions around novel zero vulnerability technol ...

In the wake of the Hypersonic race in the defense and civilian sectors, the need for new generation of heat shields that offers weight and cost reduction while maintaining performance is of absolute necessity. This work proposes a new generation of hybrid