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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Biological treatment of bacterial keratitis

    SBC: AMEBAGONE, INC.            Topic: N

    DESCRIPTION provided by applicant Staphylococcus is the most common cause of infections worldwide The pathogen persists asymptomatically on human skin from which it may spread to ocular tissues and cause corneal infection When this happens corneal bacterial keratitis can occur and if not treated effectively it may lead to blindness Multi Drug Resistant MDR variants of S aureus Sa are ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. CATALYTIC MEMBRANE REACTOR FOR THE PRODUCTION OF HYDROGEN FROM BUTANOL

    SBC: INNOVATEK, INC.            Topic: A10AT009

    A compact and efficient fuel processor that provides clean hydrogen from a high energy density liquid fuel such as butanol will allow fuel cell technology to be realized in military and commercial markets for portable applications. InnovaTek, and its proposal partner Indiana - Purdue University, will build on their combined experience in catalytic reforming to develop catalysts that are optimize ...

    STTR Phase I 2010 Department of DefenseArmy
  3. CATALYTIC MEMBRANE REACTOR FOR THE PRODUCTION OF HYDROGEN FROM BUTANOL

    SBC: INNOVATEK, INC.            Topic: A10aT009

    A compact and efficient fuel processor that provides clean hydrogen from a high energy density liquid fuel such as butanol will allow fuel cell technology to be realized in military and commercial markets for portable applications. InnovaTek, and its proposal partner Indiana - Purdue University, will build on their combined experience in catalytic reforming to develop catalysts that are optimize ...

    STTR Phase II 2011 Department of DefenseArmy
  4. Clonotyping Technology for Prediction of Antibiotic Resistance

    SBC: ID Genomics SPC            Topic: NIAID

    DESCRIPTION provided by applicant The primary goal of this Phase I STTR proposal is to develop a prototype of a rapid molecular diagnostics test to improve prediction of the antibiotic resistance of uropathogenic Escherichia coli by determining their clonal identity clonotype The clonotype determination will be done by detection of the presence absence of a limited number d of single ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. CruziScreen a recombinant antigen based screening test for Chagas disease

    SBC: PAI Life Sciences, Inc.            Topic: NIAID

    Project Summary Chagas disease is a severe inflammatory syndrome caused by infection with a protozoan parasite Trypanosoma cruzi Although transmission occurs mostly through an intermediate insect host the infection is silent and chronic carriers pose a significant risk through the transfer of infected products made from donated blood of these individuals to blood recipients Up to new c ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Custom-Fit Personal Sound Amplification Smartphone Application

    SBC: ASCENDING HEARING TECHNOLOGIES, LLC            Topic: NIDCD

    PROJECT SUMMARYPersonal sound amplification productsPSAPshave recently become available to the publicPSAPs serve a potentially important role in providing audibility of sounds for adults who have difficulty hearing in some daily living situationsbut may not be candidates for traditionalhigh amplification hearing aidsFewer thanof adults with hearing loss reporting use of hearing aidsciting high cos ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a novel highly effective influenza vaccine

    SBC: Flugen, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Seasonal influenza flu virus an NIAID category C priority pathogen causes widespread infection resulting in at least million cases of severe illness and deaths worldwide Young children and elderly or immunocompromised individuals are typically at greater risk of severe illness or death from influenza Newly emerging strains can result ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Development of Delivery Vehicle Targeting Cholinergic

    SBC: METABIOLOGICS, INC.            Topic: N/A

    N/A

    STTR Phase I 1999 Department of DefenseArmy
  9. Development of New Production Technologies for Humanized Antibodies

    SBC: ALDER BIOPHARMACEUTICALS, INC.            Topic: A04T006

    Humanized antibodies currently are produced through mammalian cell culture methods that require extensive resources, in particular, choosing the manufacturing cell line and the need for highly specialized cell growth facilities. These limitations have highlighted the need for new and more innovative ways for antibody production. Yeast heterologous protein expression systems have long been viewed ...

    STTR Phase I 2004 Department of DefenseArmy
  10. Development of a Spirulina-based oral malaria vaccine

    SBC: Lumen Bioscience, Inc.            Topic: NIAID

    ABSTRACT Vaccination represents the single most effective and cost effective medical intervention devised to datesaving lives and reducing morbidity and disability for billions of humansDespite the early success of the oral polio vaccinemost vaccines are delivered parenterallyand as such are associated with painnon compliancebiohazardous medical waste and strict requirements for expensive producti ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health

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