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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. TruEnamel: A dental product that treats, protects, desensitizes and whitens teeth

    SBC: TruEnamel, LLC            Topic: NIDCR

    DESCRIPTION provided by applicant Dentin hypersensitivity is a painful condition affecting from of the population It is caused by the movement of fluid in the dentinal tubules and can be eliminated by occluding these patent tubules Tooth whitening is a $ billion business in America and is predicted to grow both here and abroad In this grant we propose a treatment for dentin hypers ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Paper-based Rapid Diagnostics for Early Dental Caries Prediction at the Chairside

    SBC: PHASE DIAGNOSTICS LLC            Topic: NIDCR

    DESCRIPTION provided by applicant Dental caries is the single most common affliction across the globe affecting billion people The current process of identifying dental caries involves examining caries formation by naked eyes or X ray during routine checkups Once identified surgical restorative procedures are used to drill out the decay portion of the tooth an filled with synthetic mate ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. A new treatment for NSAID-associated gastrointestinal damage

    SBC: Anteana Therapeutics Inc            Topic: NIDDK

    DESCRIPTION provided by applicant Non steroidal anti inflammatory drugs NSAIDs are among the most widely consumed pharmaceuticals but their prolonged use causes gastric injury and damage to the small intestine Previous work has shown that anandamide an endogenous endocannabinoid substance produced in the gastrointestinal GI mucosa plays an important role in epithelial homeostasis and re ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. A Low Cost, Quantitative, Chemical Specific Device for Illicit Drug Detection

    SBC: MKS Technology            Topic: NIDA

    DESCRIPTION provided by applicant This proposal will assess the quantitative capabilities of surface enhanced Raman scattering SERS detection of cocaine and marijuana metabolites in urine samples Combining low cost instrumentation and novel chemical sensing provides an innovative new approach for diagnosing illicit drug use Current methods use a colorimetric indicator to screen specimens fo ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. A high-throughput kit for detection of RNA modifications

    SBC: MAVERIX BIOMICS, INC.            Topic: NIDA

    DESCRIPTION provided by applicant The broad objective of this project is to develop an integrated wet lab dry lab kit for high throughput detection of RNA modifications The final product will provide all required molecular biology reagents a set of simple and robust experimental manipulations for facile analysis of modifications and researcher friendly analytic cloud based software requi ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a biomimetic small molecule therapeutic for neovascular retinal diseases

    SBC: EyeMedix, Inc.            Topic: N

    DESCRIPTION provided by applicant Retinal diseases including age related macular degeneration AMD diabetic retinopathy DR diabetic macular edema DME and retina vein occlusion RVO are the leading causes of vision loss and blindness in people over years old According to the NEI in nearly million people in the U S suffered from some form of these diseases whose prevalen ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. A Visual Assessment System for Retinal Function/Drug Discovery

    SBC: AFASCI, INC.            Topic: N

    DESCRIPTION provided by applicant Preclinical evaluation of treatment strategies for retinal neurodegenerative diseases is highly dependent on mouse models Classical methods to assess the visual function of animals such as electroretinogram ERG which measures electrical responses in the retina do not address connections between the eye and brain or visual perception by the visual system ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. USE OF DNATrax TO MODEL THE TRANSPORT OF PARTICULATE MATTER IN URBAN ENVIRONMENTS

    SBC: DNATREK, LLC            Topic: NIEHS

    DESCRIPTION provided by applicant Science based strategies for quantifying and mitigating the impact of anthropogenic emissions on public health are essential for the sustainability of cities Similar strategies can also be used to develop and assess the effectiveness of a national defense system against terrorist attacks with airborne biological agents and protect against the spread of airborn ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Wearable Ultralow Power Personal Exposure Monitor for Atmospheric Pollutants

    SBC: KWJ ENGINEERING INC            Topic: NIEHS

    DESCRIPTION provided by applicant The goal of this STTR Phase I collaboration between KWJ Engineering KWJ and North Carolina State University NCSU will be development of a unique autonomously powered wearable environmental gas sensor for personal exposure monitoring PEM The approach will be to integrate KWJ ultralow power high performance printed amperometric gas sensor for key atmosp ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Pre-clinical Development of a Vaccine for the Treatment of Heroin Addiction

    SBC: MOLECULAR EXPRESS, INC            Topic: R42

    DESCRIPTION provided by applicant Heroin and related opioids are highly addictive drugs known for their analgesic properties Since the number of heroin users in the United States has skyrocketed reaching epidemic levels Abuse of prescription opioid pain relievers oxycodone Oxycotin and hydrocodone Vicodin which are known gateway drugs to heroin has also increased dramatically Beca ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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