Award Data

DESCRIPTION provided by applicant There is a strong unmet need for a low cost and convenient technology that can assist researchers and healthcare personnel in gathering vascular data Such vascular imaging technology could assist in the short term clinica research on the diagnostics disease progression and effect of treatment prevention strategies ...

DESCRIPTION provided by applicant The long term goal of this project is to develop an improved enzyme replacement therapeutic ERT for MPS I that integrates safety and cost advantages of plant based bioproduction with innovations that enhance ERT delivery and disease correction MPS I encompassing Hurler Hurler Scheie Scheie syndromes the most common MPS disease is caused by genetic defi ...

DESCRIPTION provided by applicant While most human papillomavirus HPV infections are short lived a subset become chronic and can progress to malignancy with much greater frequency in HIV infected individuals Only a dozen andapos high riskandapos HPV types cause cancer but HPV alone is responsible for andgt of anal cancer head and neck cancer and of cervical cancer Further and ...

DESCRIPTION provided by applicant Drug resistance is rapidly spreading among Gram negative bacteria seriously complicating the treatment of infected patients and increasing the risk of lethal outbreaks In particular carbapenem resistant Enterobacteriaceae CRE organisms associated with high mortality rate andgt have become prevalent worldwide During of long term acute car ...

DESCRIPTION provided by applicant DNA microarrays are a primary tool for DNA genotyping because of their capacity to detect multiple targets simultaneously However DNA microarrays require fluorescent labeling and long incubation steps which limit their applicability Furthermore DNA microarrays are not capable of detecting DNA targets in the presence of excess background DNA This capacity ...

The broader impact/commercial potential of this project is in various applications requiring real-time detection of toxic, explosive, and other harmful chemicals in a variety of environments. This innovative chemical sensor technology promises single-chip multianalyte sensors with significant cost savings resulting from enhanced performance, reliability, and lifetime. Developing ultra-small chemic ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is found in the proposed technology development that facilitates direct, ubiquitous acquisition of key biomedical data, with little or no human intervention or introduction of errors, has the potential to reduce the costs of healthcare and to revolutionize healthcare delivery throughout our so ...

The broader impact/commercial potential of this project is determined by new consumer products and new industries which would flourish on portable and reliable atomic clocks, gyroscopes, and magnetometers when they become available. Proposed compact thermal and magnetic enclosure reduces the most bulky part of such devices and provides an avenue for further miniaturization. A chip-scale atomic clo ...

The broader impact /commercial potential of this Small Business Innovation Research (SBIR) project will address the needs of the antibody market for fast and inexpensive production of antibodies. Antibodies are among the most utilized molecular tools in the life sciences, whose applications span a variety of areas in biological science and medicine. The worldwide antibody market was estimated at a ...

The broader impact/commercial potential of this project is in making structural simulation widely available to communities of makers, small businesses, and manufacturing enterprises, leading to dramatic improvements in performance, quality, manufacturability, and cost savings. If successful, the proposed research will result in a cloud-based simulation service, a disruptive technology holding the ...