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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Automated preparation of single-cells and nuclei from solid tissues
SBC: S2 GENOMICS, INC Topic: 172Project Summary AbstractThis project designsdevelopsand automates a novel system to process solid tissue into single cellssingle nucleiand high molecular weight DNA using disposable cartridges without user interventionThe system will support downstream single cell RNA or DNA sequencingsingle nuclei RNA or DNA sequencingand long read sequencers and optical mappingThe long term goal of the project i ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Advancing Formulation of STING agonist for Universal Flu Vaccine
SBC: IMMvention Therapeutix, Inc. Topic: NIAIDSummary Influenza virusa member of the orthomyxovirus familyhas three different types that infect humansABand CTypes A and B produce annual epidemicsand type A influenzawhich resides asymptomatically in birdscan cause pandemic infections in humansIn addition to common flu like symptomse gfeverchillsmalaisemuscle painin susceptible populations influenza can induce potentially fatal secondary compli ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A ratcheting prosthetic partial finger using advanced rapid manufacturing technology
SBC: POINT DESIGNS, LLC Topic: NICHDThe Point PartialA Ratcheting Prosthetic Partial FingerUsing Advanced Rapid Manufacturing Technology Project SummaryAbstract The goal of the proposed project is to develop a purely mechanicalratcheting prosthetic partial fingerthe Point Partialwhichhas an industry leading strength to weight ratiocan be operated unilaterallyone handedoffers anatomical rotation and flexion around the patient s proxi ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Peripheral FAAH inhibitor, URB937, as an opioid-sparing analgesic for chronic pain.
SBC: ASPIREBIO CORP Topic: 101PROJECT SUMMARY Opioid drugs are powerful analgesicsbut their side effect profile strongly limits their useIndeedtheir addictive properties have led to an epidemic of abuse in the US that accounts forof the global utilization of prescription opioid analgesics in the USwith a market of over $billion per yearPrevious studies have shown that the endocannabinoid neurotransmitteranandamidecontrols noci ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Discovery of novel CDK4/6-PI3K-BRD4 inhibitor SRX3177 for augmented anti-cancer activity
SBC: SignalRx Pharmaceuticals Inc. Topic: 102Three CDKinhibitors were recently approved to treat breast cancerBrCAin combination regimentsDespite significant clinical activitytreatment of BrCA patients with these combinations does not result in a durable responseHencethere is an unmet medical need to develop targeted therapeutic agents which will augment the activity of CDKinhibitors in BrCA and other CDKcyclin D Myc dependent malignanciesA ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Amelioration of rhinovirus induced asthma exacerbations by serpin B1
SBC: SERPLUS TECHNOLOGY LLC Topic: NIAIDPROJECT SUMMARY Asthma exacerbations are a major cause of ER visits and hospitalizations with annual direct costs of approximately $billionyear in the USAViral infectionsin particular rhinoviralRVinfectionsare a major precipitant of asthma exacerbations in allergic asthmaticsAs there are overRV serotypes andfor nowno RV vaccinenovel strategies to inhibit RV induced airway inflammation are needed t ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Protein ProFiler Microfluidic Electrophoresis System for Proteomics
SBC: INNOVAREGI LLC Topic: 400AbstractThe current estimate of the number of human genes is aboutin contrast to the number of presumed proteinswhich likely exceeds one millionThis increased complexity is the result of post transcriptional and post translational modificationsPTMsoccurring at multiple sites and in a quantitative variable mannerThe overwhelming result is a combinatorially expanding complexity of proteoforms that i ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Quantitative Biotherapeutic Particle Characterization via Deep Neural Networks
SBC: Ursa Analytics Topic: 400Project SummaryDespite their many bene ts and common useprotein based drugs can elicit serious adverse side effectsMany of these side effects are believed to be caused by small protein aggregatesOne tool for measuring these particles in a high throughput fashion is Micro ow ImagingMFIMFI is commonly used in both academia and industry to characterize subvisible particlesthosem in sizein protein the ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Point of care detection of extracellular vesicles in urine for diagnosis of preeclampsia
SBC: Sersense Inc Topic: NICHDPreeclampsiaPEis a pregnancy specific disorder characterized by hypertension and commonly by the appearance of urinary proteinThis disorder occurs inof pregnancies worldwide and is the second leading cause of maternal fetal morbidity and mortality worldwideIn low resource settingsPE accounts for up toof maternal deathsThe etiology of this disease is poorly understoodThis confounds therapeutic inte ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Software and services to advance dose-response modeling in chemical risk assesment
SBC: KS & ASSOCIATES LLC Topic: NCATSPROJECT SUMMARY Chemical risk assessment has been widely applied in chemical industry as a necessary step to get new commercial chemicals registeredand in governmental agencies as a critical procedure to evaluate the toxicity of chemicals in order to properly regulate them to protect human health and the environmentThe Lautenberg Chemical Safety Act further strengthens the importance of chemical r ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health