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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Development of Pirenzepine for HIV SN

    SBC: WinSanTor, Inc.            Topic: 101

    PROJECT SUMMARY Over million people worldwide including million people in the USA are HIV positive HIV associated sensory neuropathy HIV SN is the most frequent neurological manifestation of HIV and is characterized as a distal symmetrical predominantly sensory polyneuropathy HIV SN may represent clinically indistinguishable neuropathies with distinct pathogenesis a distal axona ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Develop technology platform to transform the diagnosing monitoring and treating of opioid use disorders

    SBC: Mentor On The Go, LLC            Topic: NIDA

    PROJECT ABSTRACT There are two big challenges to reducing the number of substance use disorders SUDs in the United States Almost of the million people who suffer from SUDs are never professionally diagnosed and never seek treatment and treatment for the small minority that does seek help is not very effective with relapse rates estimated to be between and within ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Direct magnetic characterization of individual nanoparticles for optimized diagnostic imaging

    SBC: ODMR Technologies, Inc            Topic: 101

    Project Summary ODMR Technologies Inc and Prof Victor Acostaandapos s group at University of New Mexico UNM are developing a diamond chip platform capable of direct magnetic characterization of individual nanoparticles for optimized diagnostic imaging Our team is a spinoff from academic collaborations in the emerging field of diamond photonic sensors a field we helped create nearly a deca ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Empowering real time web based genomic big data analysis at commercial scale

    SBC: Frameshift Labs, Inc.            Topic: 172

    DESCRIPTION provided by applicant The academic iobio project delivers web based applications that visualize and provide real time interactive analysis with multiple different data types generated as part of next generation sequencing projects These applications are open source and provided for free This proposal aims to develop critical computational infrastructure to enable the iobio project ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Enabling point of care molecular diagnostics by developing an adaptive PCR instrument and on demand kit reagents

    SBC: BIOVENTURES, INC            Topic: 172

    Because of its high sensitivity polymerase chain reaction PCR is the gold standard for the diagnosis of many infectious diseases but generally only implemented in well equipped laboratories One of the major roadblocks for expanding PCR to point of care markets is the lack of simple robust single tube PCR designs which preserve its laboratory based high sensitivity and specificity In this F ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Epigenetic Markers and Sustained Cytoprotection for Stroke Treatment

    SBC: ZYMO RESEARCH CORP.            Topic: 101

    PROJECT SUMMARY ABSTRACT Stroke injury is a process that occurs over a long duration with pathologic changes that result in long term neurologic dysfunction For stroke there exists an important need for a strategy that can provide safe and efficacious stabilization to the hypoperfused brain and initialize long lasting endogenous neuroprotection for prevention of long term neurologic dysfunction ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Gold nanoparticle laser warming of cryopreserved zebrafish embryos

    SBC: NANOCOMPOSIX, INC.            Topic: OD

    Project Summary Abstract In the past decade laboratories around the world have produced tens of thousands of mutant transgenic and wild type zebrafish lines for a wide range of genetic and biomedical research Maintaining all of these valuable genotypes is expensive risky and beyond the capacity of even the largest stock centers Cryopreservation of zebrafish sperm eggs and embryos is vital ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications

    SBC: GENECAPTURE            Topic: CBD15C001

    The modern warfighter faces the constant threat of endemic infections, multi-drug resistant bacteria and Biological Warfare Agents. In order to provide accurate front-line treatment that will curtail the overuse of antibiotics, a rapid and robust molecula

    STTR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  9. Integrated Platform for Mass Spectrometric Studies of Protein Structure

    SBC: Protein Metrics Inc.            Topic: 100

    Summary Technology for studying the higher order structure HOS of biomolecules encompasses some of the most important tools in all of science and is a highlighted NIGMS research topic Mass spectrometric methods for studying HOS include oxidative footprinting and other methods to covalently label amino acid side chain functional groups and also hydrogen deuterium exchange HDX on protein bac ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Integrated tools for higher order structure determination by cross link analysis

    SBC: Protein Metrics Inc.            Topic: 100

    Summary The use of mass spectrometry MS for quantitative protein characterization has increased dramatically identifying and quantifying thousands of proteins is no longer a heroic task nor is characterizing therapeutic proteins in detail Due to widely available software quantitative mass spectrometry has become routine and widely used for addressing questions in basic biology translational ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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