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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Predictive In Vitro Model for Screening Personalized Responses to CFTR-directed Therapeutics

    SBC: CFD RESEARCH CORPORATION            Topic: NHLBI

    Abstract The objective of this study is to develop a novel predictive in vitro model for personalized responses to CFTR directed therapeutics This proposal responds to RFA HL Human Cellular Models for Predicting Individual Responses to Cystic Fibrosis Transmembrane Conductance Regulator Directed Therapeutics Cystic fibrosis CF is a life shortening genetic disease caused by loss of ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. A product for osteoarthritis treatment and prevention

    SBC: NEW YORK R & D CENTER FOR TRANSLATIONAL MEDICINE & THERAPEUTICS INC            Topic: R

    DESCRIPTION provided by applicant Osteoarthritis OA is the most common form of arthritis and the leading cause of disability in adults and the aging population There is no cure for OA Current treatments mainly focusing on pain management and improving or sustaining function and have no clearly demonstrated beneficial effect on chondroprotection or OA disease modification Long term use of ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Aptamers and BSI for Sub-Microliter Analysis of Pharmaceuticals in Neonatal Urine

    SBC: BASE PAIR BIOTECHNOLOGIES INC            Topic: NICHD

    DESCRIPTION provided by applicant Neonatal and pediatric intensive care still involves performing painful needle punctures to obtain blood samples for routine clinical monitoring Pain management in the neonatal setting is often achieved by long term continuous intravenous infusion of morphine or related compounds It has become increasingly clear however that long term use of opioid compound ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. A Rapid Point-of-Care Assay for the Diagnosis of Lyme Disease

    SBC: BIOPEPTIDES CORP            Topic: NIAID

    DESCRIPTION provided by applicant Lyme disease caused by infection with Borrelia burgdorferi is the most common vector borne infectious disease in North America and Europe Early disease can be effectively cured with antibiotics however untreated late disseminated infection can result in permanent damage to the nervous and musculoskeletal systems Therefore early diagnosis is critical for ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. ARCHER- An Extremely Fast Medical Radiation Dose Computing Software

    SBC: VIRTUAL PHANTOMS INC            Topic: NIBIB

    DESCRIPTION provided by applicant The goal of this project is to develop a commercial software package for rapid Monte Carlo based dose computation in imaging and radiation therapy The product takes advantage of a desktop parallel computer equipped with emerging hardware originally developed gaming and high performance computing The project is motivated by the fact that the market is ripe for ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. A sample-to-answer diagnostic cartridge that identifies influenza using a glucometer

    SBC: Paratus Diagnostics            Topic: NIAID

    Project Summary Abstract Seasonal influenza has an annual global incidence of up to in adults and up to in children About to million infections result in severe disease while somewhere between a quarter and a half million cases are fatal Antiviral drugs can lessen the severity and reduce mortality when administered within h of onset of symptoms Hence sensitive and specific poin ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. A simple and effective diagnostic test for gastrointestinal bleeding to improve patient outcomes

    SBC: CUMBERLAND PHARMACEUTICALS, INC.            Topic: 300

    DESCRIPTION provided by applicant Problem Lower gastrointestinal bleeding is a significant medical problem in the United States accounting for more than hospital admissions and tens of billions of dollars of healthcare spending annually It is common for bleeding from a single site to stop and restart multiple times The three modalities now used to diagnose and locate gastrointestina ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. A small molecule integrin activator to enhance cord blood transplant

    SBC: 7 Hills Pharma LLC            Topic: NHLBI

    DESCRIPTION provided by applicant This proposal is in response to PA the parent announcement for STTR R grant applications Hematopoietic stem cell transplantation has become a preferred treatment for hematological malignancies and certain genetic disorders The use of umbilical cord blood cells as a source of hematopoietic stem cells for bone marrow transplantation has increased st ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. A smartphone-based point-of-care test for detection of Chlamydia trachomatis

    SBC: LUMINOSTICS INC            Topic: NIAID

    DESCRIPTION provided by applicant Significance The ultimate goal of this project is a CE marked FDA cleared and CLIA waived rapid andlt min smartphone based point of care POC test to aid the diagnosis of Chlamydia trachomatis CT infections CT infections are the most common bacterial STI with almost million new cases in the US each year and associated costs exceeding $ billion ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. A targeted drug for the treatment of inflammation in cystic fibrosis lung disease

    SBC: NANOMETICS LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Problem to be Solved Cystic fibrosis CF is a global health issue that affects over people worldwide including Americans Lung disease is the primary cause of morbidity and mortality in CF patients and is characterized by intense inflammatory responses in the airways The Product and Long Term Goal Nanometics LLC dba PHD Biosciences PHD ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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