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The Award database is continually updated throughout the year. As a result, data for FY22 is not expected to be complete until September, 2023.
Download all SBIR.gov award data either with award abstracts (290MB)
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A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care ApplicationsSBC: GeneCapture, Inc. Topic: CBD15C001
The modern warfighter faces the constant threat of endemic infections, multi-drug resistant bacteria and Biological Warfare Agents. In order to provide accurate front-line treatment that will curtail the overuse of antibiotics, a rapid and robust moleculaSTTR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
Detecting Substandard, Nonconforming, Improperly Processed and Counterfeit MaterielSBC: VIBRANT CORPORATION Topic: DLA15C001
Vibrant Corporation and Sandia National Laboratories (SNL) propose to apply Process Compensated Resonance Testing (PCRT) to the DLA's need for an NDI method to detect counterfeit, nonconforming and improperly processed materiel. PCRT collects and analyzes the resonance frequencies of a component to detect structural defects, characterize material, analyze population variation, monitor manufacturin ...STTR Phase I 2016 Department of DefenseDefense Logistics Agency
Hybridized Additive Manufacturing for Medical Equipment (HAMME) technologySBC: Interlog Corporation Topic: DLA152002
To address the Defense Logistics Agency (DLA) needs for 3D printing technology for the medical supply chain, Interlog Corporation proposes to develop a new Hybridized Additive Manufacturing for Medical Equipment (HAMME) technology enabling to build multiple material equipment/supplies in a single platform. The HAMME is based on a unique, precision instantaneous energy generation mechanism providin ...SBIR Phase I 2016 Department of DefenseDefense Logistics Agency
Mycotoxin Neutralization TreatmentSBC: Physical Optics Corporation Topic: CBD152003
To address the Chemical and Biological Defense programs (CBDs) need for medical countermeasures against mycotoxin intoxication, PhysicalOptics Corporation (POC) proposes to develop a new Mycotoxin Neutralization Treatment (MyNT). This proposed solution is based on neutralizingmycotoxin from its deleterious effects by acting on multiple levels of mycotoxin metabolism through the novel combination o ...SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
Exploiting Microbiome and Synthetic Biology to Discover and Produce Naturally Occurring AntibioticsSBC: Radiant Genomics, Inc. Topic: CBD152004
In this proposal, we aim to validate the human gut microbiome and arid soil as a source of antibiotic natural products (NPs ) by using ametagenomic NP discovery platform developed at Radiant Genomics. Recent studies suggest that the genomes of uncultivated microorganisms,like their cultivated counterparts, encode an enormous number of NPs. Gaining systematic access to NPs using standard, cultivati ...SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
Producing Novel Biosynthetic Therapeutics from Extreme MicrobiomesSBC: iXpressGenes, Inc. Topic: CBD152004
Environmental DNA from three extreme samples will be isolated, cloned into a fosmid library (5760 clones) for sequencing. The sequencing datawill cover ~ 240 Megabases and will be assembled into contigs long enough (~ 40 Kilobases) to represent potential biosynthetic gene clusters(BGCs). This data will be compared to BGC databases looking for homology to antibiotic targets of DoD interest and with ...SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
Wavelet-Based Approach for Signal Processing and AnalysisSBC: Physical Optics Corporation Topic: CBD152006
To address CBDs need for development of analytical approaches to fuse sensor data from multiple modalities to provide common operationalpictures in threat environments, Physical Optics Corporation (POC) proposes to develop a Wavelet-based Approach for Signal Processing andAnalysis (WASP). WASP is based on novel application of wavelet-based analysis to multimodel, multidimensional data available fr ...SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
Signal Processing for Layered SensingSBC: TOYON RESEARCH CORPORATION Topic: CBD152006
As a foundational component of a Layered Sensing architecture, Toyon proposes to develop a Multi-Modal Fusion Module (M2FM) capable ofconfirming detections from Chemical, Biological and Radiological (CBR) sensing networks by fusing together information from other (non-CBR)sensors. The module will provide information to assist operators in confirming an initial CBR detection or rejecting it as a fa ...SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
Exploiting Natural Products-Based Therapeutics for Aflatoxin MitigationSBC: CFD RESEARCH CORP Topic: CBD152003
Aflatoxins are a paradigm among fungal produced mycotoxins that are present in food supplies and are strongly associated with increased risk forthe development of hepatocellular carcinoma. Currently, there are no known countermeasures that can selectively mitigate aflatoxin toxicity andthe available options are only symptomatic treatments. To meet this challenge, we propose to harness the microbio ...SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense