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Award Data
The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Intravascular molecular-structural NIRF-IVUS imaging of coronary artery disease
SBC: IntraVascular Imaging, Inc. Topic: NHLBIThe goal of this Phase I STTR project is to constructoptimizeand test a clinically viable intravascular near infrared fluorescence intravascular ultrasoundNIRF IVUSimaging catheter for simultaneous molecular and structural diagnosis of coronary artery diseaseCADCAD is a worldwide leading cause of death and disabilityincluding acute myocardial infarctioncongestive heart failureand sudden cardiac de ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Innovative Nose-to-Brain Anticancer Drug Transport Facilitated by NEO100
SBC: NEONC TECHNOLOGIES INC Topic: 102Project Summary Abstract Many pharmaceutical agents are highly potentbut are unable to exert substantial therapeutic activity against disorders of the brainbecause the blood brain barrierBBBeffectively prevents their access to the site of intracerebral diseaseFor examplethe majority of glioblastoma patientsdespite the best efforts of current medical caredie within two years after diagnosisHencethe ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Reopening the Central Airway With Needle-Size Tentacle Manipulators
SBC: VIRTUOSO SURGICAL, INC. Topic: NHLBIProject Summary AbstractThe objective of this proposal is to perform proof of concept experiments on a new hand held surgical instrument that provides dexterity at the tip of a rigid bronchoscopeThis approach is less invasive than traditional open surgeryand will be safer than the current rigid bronchoscopic approachwhich lacks dexterity in port delivered instrumentsOur new system will feature nee ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Novel Indication for Myeloid Progenitor Use: Induction of Tolerance in Solid Organ Transplantation
SBC: Cellerant Therapeutics, Inc. Topic: NIAIDPROJECT SUMMARY State of the art techniques result inyear solid organ graft loss ofto overin cardiopulmonary organ transplantationEstablishment of donor specific immunological toleranceDSITa condition in which a recipient accepts a transplant without immunosuppressionwhile retaining the ability to fight infectionswould reduce graft loss and transplant related complicationsThe only identified metho ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Development of a Clinical Screening Platform for Type 1 Diabetes
SBC: Op-T-Mune, Inc Topic: NIDDKAbstractA major shortfall in clinical care for diabetes is a rapid and accurate screen for progression to diseaseCurrent criteria involve HLA haplotypeand the presence of auto antibodiesAAGenome wide associated studiesGWASrevealed only immune associated genes including HLA as T D predictorsThe ability to differentiate from other diseases was very limitedPre typediabetesp T Dis now being identified ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Advancing a novel portable detection method for cannabis intoxication
SBC: Brain Solutions, LLC Topic: NIDATBD
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
A Novel Therapeutic that Harnesses Microtubules to Promote Cavernous Nerve Regeneration after Radical Prostatectomy
SBC: MICROCURES INC Topic: 300Radical prostatectomyRPis a commonly used treatment option for localized prostate cancerUnfortunatelythe procedure carries a risk of post surgical complications including a high risk of erectile dysfunctionEDAccording to The Prostate Cancer Outcomes Studyvirtually all men experience ED after surgeryincluding a profound loss of nocturnal erectionsThe Prostate Cancer Outcomes Study further reveals t ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A Novel Therapeutic that Harnesses MIcrotubules to Enhance Corneal Wound Healing Following an Alkaline Burn
SBC: MICROCURES INC Topic: NEIThe cornea is one of the most important tissues in the eye and its transparency is critical for good visual function in humansCorneal tissue injuries are the most common everyday issue for practicing ophthalmologists and can run the gamut in severityIn severe modelssuch as corneal alkaline burnsextensive healing is needed and often the burn victim is left with reduced visual acuityHealing of large ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Preclinical Development of 2nd Generation HIV Maturation Inhibitors
SBC: DFH Pharma, Inc Topic: 400Project SummaryDespite advances in the development of HIV drugs there remains a need for new therapiesToxicities associated with long term use of many of the approved HIV drugs coupled with the development of resistance drives the need for new and novel antiviralsMaturation inhibitorsMIsrepresent one such class of HIV therapiesHIV maturation inhibitors block virus replication by disrupting the con ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Exploration of Low-Cost Long-Timescale Free Energy Perturbations on FPGAs
SBC: Silicon Insite, Inc. Topic: 400Drug discovery is challenging and expensiveespecially in the phase of lead optimization whichpredicts binding to a targetComputational approaches can add substantial valueComputingrelative binding free energiesRBFEbetween congeneric molecules using molecular dynamicsMDgreatly reduces the search space and considerably improves convergenceThe Silicon TherapeuticsSTXINSITE platform uses an RBFE proto ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health