Award Data

Through this STTR contract, we propose to evaluate the efficacy of our vaccine, FlowVax Marburg, in nonhuman primates (NHPs). This will be achieved through four Tasks. In Task 1, we will manufacture the vaccine in a quantity sufficient for the animal studies. In Task 2, we will perform MHC genotyping on a representative population of NHPs and, based on results, select a set of MHC-matched NHPs for ...

There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terrible morbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditional vaccines have contributed greatly to public health, they have some limitations especially in the context of operati ...

Additive manufacturing (AM) bring revolutionary capabilities and is very attractive to various commercial and military applications. However, metal AM often results in components with various defects, which may have decisive impact on their mechanical properties. To address this critical concern of AM quality, in this research, Intelligent Automation, Inc (IAI) will develop and implement a materia ...

Materials for thermal protection are required to protect structural components of missile launching systems, space vehicles during the re-entry stage, and solid rocket motors (SRMs). Polymer resins that have high char retention (e.g., phenolic resins) are the most common matrices in the composite materials for rigid thermal protection systems (TPSs) due to their tunable density, lower cost, and hi ...

The objective of this project is to advance the capabilities of the Coastal Battlefield Reconnaissance and Analysis (COBRA) system by creating a Surf Zone Modelling Tool (SZT) that can create realistic synthetic imagery of the surf zone (SZ). Through the use of this synthetic imagery the COBRA Program will be enabled to inform concept of operations (CONOPS) in unfamiliar environments as well as mo ...

Digital equalizers have been the major enablers in RF communications in terms of managing component imperfections and channel impairments. Specifically, the ever increasing processing power of the dedicating computing processors has availed a steady increase in the ability of complex communication systems to deal with impairments as well as allowing higher capacities in the information transfer.On ...

This proposal is a collaborative effort between MRV Systems and the Woods Hole Oceanographic Institution. The goal is to develop a new, small, inexpensive autonomous vehicle to investigate mixed layer dynamics and turbulent mixing. The preliminary Phase I design, a Diagonally Operating Platform (DOP), is a profiling float with moveable fins. DOP will turn toward an intended direction within a few ...

Current design tools for gas turbine engines invoke a variety of simplifying assumptions to estimate heat transfer to solid/metal engine components (e.g., isothermal boundary conditions). These approximations are often not valid, result in inaccurate predictions of heat transfer, and ultimately compromise the thermal integrity of propulsion and power systems. Wall-modeled large eddy simulation (WM ...

Additive manufacturing (AM) is a very promising technique for rapid, low-cost production of aircraft parts directly from a CAD file. AM is especially appealing for complex parts that would be costly or impossible to fabricate by machining or casting. At the current time there are no reliable, cost-effective techniques to qualify the finished parts. Several government studies have noted this gap an ...

Robotic Research, LLC (RR) and Southwest Research Institute (SwRI) are creating a prototype Learning-based Approach for Relevant Data Extraction (LARDE). The LARDE framework is a data extraction and handling framework that can intelligently reduce the volume of raw data from on-board sensors, and organize and persistently store the reduced relevant dataset.