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SBC: Arete Associates Topic: DTRA162002
Aret Associates and Oak Ridge National Laboratory (ORNL) propose an interdisciplinary effort to further develop and validate a robust, operational biomonitoring application that can process soil microbiome data to reliably detect episodic and low-level chronic contamination while maintaining low false alarm rate.The Phase II SBIR work will build upon the successful Phase I proof-of-concept demonst ...SBIR Phase II 2018 Department of DefenseDefense Threat Reduction Agency
SBC: Flow Pharma, Inc. Topic: CBD18A002
Flow Pharma, Inc. is a biotechnology company in the San Francisco Bay Area developing fully synthetic cytotoxic T lymphocyte (CTL)stimulating peptide vaccines for Marburg virus. The FlowVax vaccine platform allows us to create dry powder formulations of biodegradablemicrospheres and TLR adjuvants incorporating class I and class II T cell epitopes. FlowVax vaccines can be designed for delivery by i ...STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
SBC: Luna Innovations Incorporated Topic: CBD18A002
Marburg virus (MARV) is a filamentous enveloped non-segmented negative sense RNA virus. This viruse is considered to be extremelydangerous with case fatality rates as high as 88-90%. Extensive efforts have gone towards effective vaccines for MARV prevention, however,none have been successfully established as licensed vaccines. Glycoprotein (GP) is the only surface protein of MARV. There are substa ...STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
SBC: CLOSTRA INC Topic: DTRA162001
Deep Learning for standoff detection of Special Nuclear Material (DLeN) applies the same deep learning techniques that allow computers to beat human performance in image recognition and the game of Go to detecting Special Nuclear Material. Spectral analysis and signal processing can in some cases be augmented by the use of much larger neural nets that conduct much deeper analysis of features of th ...SBIR Phase II 2018 Department of DefenseDefense Threat Reduction Agency
SBC: SCIENTIFIC APPLICATIONS & RESEARCH ASSOCIATES, INC. Topic: DTRA16A004
For effective protection against radiated threats, it is important to understand not only the physics of the threats, but also to quantify the effects they have on mission-critical electrical systems. Radiated vulnerability and susceptibility testing requires delivery of high peak power and peak electric fields to distant targets. The most practical solution to simulate such environments on large ...STTR Phase II 2018 Department of DefenseDefense Threat Reduction Agency
Hierarchical, Layout-Aware, Radiation Effects Tools Vertically Integrated into an EDA Design Flow for Rad-Hard by DesignSBC: RELIABLE MICROSYSTEMS LLC Topic: DTRA16A003
The goal of this workis to establish a radiation-aware capability in a commercial EDA design flow that will enable first-pass success in radiation resiliency for DoD ASIC designs in much the same way that existing EDA design suites ensure first pass functionality and performance success of complex ASICs destined for commercial applications.Such an integrated capability does not presently exist.The ...STTR Phase II 2018 Department of DefenseDefense Threat Reduction Agency
SBC: ZYANTE INC. Topic: 91990018R0006
In this project, the team will develop a prototype of a web-based coding progression tool for high school students to practice coding from easy to successively harder levels. The prototype will provide graded practice exercises, solutions, and explanations for important coding tasks. At the end of Phase I, in a pilot study in five high school classrooms, the researchers will examine whether the pr ...SBIR Phase I 2018 Department of EducationInstitute of Education Sciences
SBC: StoryWorld International Corporation Topic: 99190018R0005
Purpose: In prior research and development, the project team developed Storyworld, a web-based activity with mini-games to support English Learners (EL) in language acquisition. In this project, the team will fully develop and test a formative assessment dashboard that provides teachers with insights into EL student's progress as they use Storyworld. ELs are the fastest-growing student population ...SBIR Phase II 2018 Department of EducationInstitute of Education Sciences
SBC: Simbulus, Inc. Topic: 99190018R0005
Purpose: This project team will fully develop and test Woot Math Polls, a formative assessment dashboard that converts student math work into data-driven insights to inform teacher instruction and student learning in middle and high school algebra classrooms. Research has marked a decline in math achievement around the time students take algebra in middle school. Technological innovations that pro ...SBIR Phase II 2018 Department of EducationInstitute of Education Sciences
SBC: MIDSCHOOLMATH, LLC Topic: 99190018R0005
Purpose: This project team will fully develop and test Fate and Fortune, an online class-wide intervention where grade 8 students learn algebra within a story-based game. Research demonstrates that students who do not succeed in algebra are more likely to eventually drop out of high school. When students begin Algebra I, a lack of conceptually meaning and understanding can be further reinforced by ...SBIR Phase II 2018 Department of EducationInstitute of Education Sciences