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SBC: INNOSENSE CORPORATION Topic: DHP16006
DoD requires a single, multiplexed, saliva-based diagnostic bioassay to determine multiorgan injury-relevant systemic toxicity. This assay should quantitatively-detect clinically relevant biomarkers in saliva and validate organ injury arising from chemical/xenobiotic exposure. Innosense LLC (ISL) is building on its proprietary carbon nanotube platform to construct Nano-Mos for detecting salivary b ...SBIR Phase II 2017 Department of DefenseDefense Health Agency
SBC: INTELLIGENT OPTICAL SYSTEMS INC Topic: DHP16006
Rapid diagnosis in conflict areas is a growingmilitary need, as troops areexposed to chemical threats (http://www.army.mil/e2/c/downloads/351235.pdf). Testingfor biomarkers in saliva has recently shown great promisein diagnostics, prognostics, and treatmentefficacy follow-up. In addition to itsconveniencefor field sampling and rapid testing,saliva is a rich body fluid with a number of physiologica ...SBIR Phase II 2017 Department of DefenseDefense Health Agency
SBC: Physical Optics Corporation Topic: CBD171004
To address the CBD’s need for real-time analytical technology for multicomponent vapor identification and quantification, Physical Optics Corporation (POC) proposes to continue the development of a new Photoacoustic Gasses Optical Detector and Analyzer (PAGODA) autonomous, network-enabled photoacoustic spectrometer (PAS) for the correlation, analysis, and identification of measured spectra. In t ...SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
SBC: HEDGEFOG RESEARCH INC. Topic: DHP16004
Despite recent tremendous leaps in the development of new technologies for image recording, presentation, manipulation, 3D capabilities, and analysis, many vision exams are still performed using paper Snellen charts, paper color charts and Amsler grids. Current procedures are time consuming, labor intensive, potentially subject to transcription errors and test preparation, which may compromise the ...SBIR Phase II 2017 Department of DefenseDefense Health Agency
SBC: iXpressGenes, Inc. Topic: CBD152004
This project is a unique metagenomic evaluation of under-studied extremophilic microbiome natural products (NPs), with the goal of discovering novel antibiotic biowarfare agent (BWA) countermeasures. A metagenomic biosynthetic gene cluster library from extremophilic sources was created, sequenced, analyzed, and exploited to produce several broad-spectrum antibiotic extracts during the Phase I effo ...SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
SBC: SA PHOTONICS, LLC Topic: DHP16004
Existing visual screening devices consist of illuminated test cards. By rotating the knob, images may be changed; however, once the system is loaded with cards it cannot be easily reconfigured. There are a limited number of cards that a unit can hold at one time, and it is impossible to change cards on the fly if a patients vision needs further investigation or if the clinician wants to do variabl ...SBIR Phase II 2017 Department of DefenseDefense Health Agency
SBC: CFD RESEARCH CORPORATION Topic: CBD152003
Aflatoxins B1 (AFB1) are fungal produced mycotoxins that are present in food supplies and are strongly associated with increased risk for thedevelopment of hepatocellular carcinoma. Currently, there are no known countermeasures to selectively mitigate AFB1 toxicity. To meet thischallenge, we successfully validated a Phase I proof-of-concept study to harness the microbiome extracts of scavenging ma ...SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
SBC: CFD RESEARCH CORPORATION Topic: DHP16005
Iron deficiency is one of the most common nutritional deficiencies in the United States. Left untreated, iron stores continue to deplete, resulting in iron deficiency anemia (IDA). Women undergoing basic military training are particularly susceptible to reduced and depleted iron stores. To-date, there are no point-of-care (POC) instruments for comprehensive, accurate determination of iron status. ...SBIR Phase II 2017 Department of DefenseDefense Health Agency
SBC: SA PHOTONICS, LLC Topic: DHA172005
In a multiple patient situation, the medics need all the help they can get. Monitoring several patients is a difficult task, and associating the vital signs data with the right patient is crucial. Providing medics with a tool to assist in this task can grSBIR Phase II 2019 Department of DefenseDefense Health Agency
SBC: Kalyra Pharmaceuticals, Inc. Topic: NonDOD
There has been considerable interest in the development of alternative therapies for pain management that are neither opioid nor non-steroidal anti-inflammatory drugs (NSAIDs). Kalyra Pharmaceuticals has demonstrated that acetaminophen, also known as APAPSBIR Phase II 2017 Department of DefenseDefense Health Agency