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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Goldmann Contact Tonometry with Optimized Error Correction

    SBC: CATS TONOMETER LLC            Topic: NEI

    Intuor Technologies, LLC - Project Summary Goldmann Contact Tonometry with Optimized Error Correction Intraocular pressure (IOP) measurement is a very important criteria used to assess visual acuity when eye care professionals are diagnosing, treating, and managing potential glaucoma patients. Goldman tonometry (GAT) IOP is recognized as the “gold standard”, but GAT IOP measurements errors hav ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a New Carbohydrate-based Anticoagulant Drug

    SBC: GLYCAN THERAPEUTICS CORPORATION            Topic: NHLBI

    Low molecular weight heparins (LMWHs) are partially depolymerized natural products of heparin, which are isolated from porcine intestine. A worldwide distribution of contaminated heparin in 2007 was associated with 85 deaths in the US. This crisis revealed the vulnerability of the LMWH supply chain. LMWHs are complex mixtures, having average molecular masses of 3500-6000 Daltons, corresponding to ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Low cost retinal optical coherence tomography for point of care use

    SBC: Lumedica, Inc            Topic: NEI

    The objective of this research is to create a clinical prototype of a new optical coherence tomography (OCT) system suitable for diagnostic retinal imaging at the point of care. The target system price will be one third the price of currently available research OCT systems while providing performance comparable to other entry level OCT imaging systems. By breaking the $15,000 system barrier we wil ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. New Class of Bright, Sharp, Tunable Near-Infrared Fluorophores for Flow Cytometry

    SBC: Nirvana Sciences, Inc.            Topic: NIAID

    Abstract Polychromatic flow cytometry (FC) is one of the most powerful analytical techniques routinely used by both basic research and clinical diagnostics laboratories for the immunological categorization of cells. Dyes used for FC typically exhibit broad fluorescent emission bands with full-width-at-half-maximum (fwhm) values of 50–80 nm. This limits the maximum number of dyes, and thus the nu ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Mindfulness Mobile App to Reduce Adolescent Substance Use

    SBC: OREGON RESEARCH BEHAVIORAL INTERVENTION STRATEGIES, INC.            Topic: NIDA

    Abstract Adolescents in the juvenile justice system demonstrate very high rates of tobacco, alcohol, and other drug use (ATOD), with rates that are estimated to be three times higher than non-justice-involved youth. Substance- abusing youth – especially those who are involved in the juvenile justice system – are at higher risk than nonusers for mental health problems, including depression, con ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. A Comprehensive Newborn Screening Solution for Duchenne and Congenital Muscular Dystrophies

    SBC: BAEBIES, INC.            Topic: NICHD

    Congenital genetic abnormalities are a leading cause of childhood mortality and morbidity. While routine newborn screening (NBS) has dramatically improved health outcomes, many congenital disorders such as Duchenne muscular dystrophy (DMD) and other congenital muscular dystrophies (CMD) are not currently detected by routine NBS. Presymptomatic identification through NBS is critical to facilitate e ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. ALow Blood Volume Platform for Global Newborn Screening of Common, Treatable Conditions

    SBC: BAEBIES, INC.            Topic: NICHD

    An estimated 80% of babies born worldwide (approximately 100 million each year) currently do not receive any newborn screening care. Newborn screening (NBS) is an immensely successful testing program that identifies those at increased risk for common, treatable congenital disorders; the pre-symptomatic identification of these disorders in newborns enables the rapid initiation of treatments and red ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. HLS-Affordable, quantitative microchip-electrophoresis for sickle cell disease screening

    SBC: HEMEX HEALTH INC            Topic: NHLBI

    PROJECT SUMMARY Sickle Cell Disease (SCD) affects 100,000 Americans and more than 14 million people globally, primarily in economically disadvantaged populations. It is estimated that nearly 50-90% of children born with SCD in these areas die before the age of five, although 70% could be saved through simple, cost-effective treatments if diagnosed early according to World Health Organization. Earl ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Nano-Oscillator Arrays for Sensitive Plasmonic Detection of Molecular Interactions and Reactions

    SBC: BIOSENSING INSTRUMENT INC            Topic: 400

    Detecting molecular interactions and reactions are basic tasks to understand biochemical processes in living organisms, discover biomarkers and develop drugs. Today’s mainstream commercial detection technologies are based on measuring mass changes, which struggle to detect small molecules (e.g., metabolites, hormones, and neurotransmitters), and biochemical reactions involving small mass changes ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Sustained release gel enabling one-stage treatment of prosthetic joint infection

    SBC: SONORAN BIOSCIENCES INC            Topic: NIAID

    Prosthetic joint infections (PJIs) are a serious complication of total joint replacement surgery. PJIs accounted for about $6 billion in healthcare costs in 2018. Unfortunately, treatment of PJI is under-reimbursed, and healthcare reforms are putting increasing economic pressure on hospitals to bear the high costs of treating these infections. New technologies are badly needed to improve the quali ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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