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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 11 - 20 of 6435 results
  1. A Bioactive Prosthetic Vascular Graft

    SBC: BIOSURFACES INC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Over 60,000 prosthetic grafts, which are primarily comprised of polyethylene terephthalate (polyester) or expanded polytetrafluoroethylene (ePTFE), are implanted in the United States each year. Unfortunately, these grafts continue to have high failure rates due to secondary complications associated with acute thromboses and incomplete, unregulated cellular prol ...

    STTR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  2. A Biodegradable Vascular Coupling Device for End-to-End Anastomosis

    SBC: Microsurgical Innovations Inc            Topic: NHLBI

    Project Summary The objective of this Phase I SBIR proposal is to demonstrate the feasibility of a device designed to connect two small vessels together simply and easily and that would replace the hand suturing technique currently used to connect vessels in microsurgery and macrovascular end to end vascular repair surgeries This completely biodegradable vascular coupling device VCD being devel ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. A Biodegradable Vascular Coupling Device for End-to-End Anastomosis

    SBC: Microsurgical Innovations Inc            Topic: NHLBI

    Project Summary The objective of Microsurgical InnovationsMSIin this proposal is to develop a biodegradable vascular coupling deviceVCDwhich would replace the hand suturing technique currently used to connect arteries and veins in microvascular and macrovascular end to end vascular repair surgeriesOur device works for both arteries and veins and can rapidly connect the two vessel ends together in ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. A biologically-inspired, interactive digital device to introduce K12 students to computational neuroscience

    SBC: BACKYARD BRAINS INCORPORATED            Topic: 500

    PROJECT SUMMARY Understanding the brain is a profound and fascinating challenge, captivating the scientific community and the public alike. The lack of effective treatment for most brain disorders makes the training of the next generation of neuroscientists, engineers, and physicians a key concern. However, much of neuroscience is perceived to be too difficult to be taught in school. Having alread ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  5. A BIOMATERIAL FOR ESOPHAGEAL REPAIR

    SBC: ACELL, INC.            Topic: N/A

    DESCRIPTION (Unedited Applicant's Abstract):When people with diabetes reach end-stage renal disease they must undergo either dialysis or transplantation. About 200,000 Americans need artificial kidney machines to stay alive. These machines rely on sterile dialysis membranes to remove toxic materials from the bloodstream. More than 30 different polymers or polymer blen ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  6. A BIOMATERIAL FOR ESOPHAGEAL REPAIR

    SBC: ACELL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): ACell is a tissue engineering company and its core technology is based upon a porcine derived extracellular matrix (ECM) harvested from the urinary bladder (UBM) that serves as a constructive scaffold for tissue reconstruction. Successful completion of Phase I studies showed that the UBM-ECM can be configured into a tube shaped device with mechanical and materi ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  7. A BIOMATERIAL FOR ESOPHAGEAL REPAIR

    SBC: ACELL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): ACell is a tissue engineering company and its core technology is based upon a porcine derived extracellular matrix (ECM) harvested from the urinary bladder (UBM) that serves as a constructive scaffold for tissue reconstruction. Successful completion of Phase I studies showed that the UBM-ECM can be configured into a tube shaped device with mechanical and materi ...

    SBIR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
  8. A Bioscaffold for Repair of Congenital Defects

    SBC: ACELL, INC.            Topic: N/A

    DESCRIPTION (Verbatim from the Applicant's Abstract): This Phase I SBIR application seeks support to develop and evaluate a naturally-occurring extracellular matrix (ECM) bioscaffold material for tissue engineering applications; specifically, the repair and/or restoration of congenital defects in which lost or missing tissue is the limiting factor for s ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  9. A biosensor to detect ERE-binding proteins in cancer

    SBC: IA, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Biosensors provide rapid data containing information on molecular interactions that are not easily available using equilibrium assays or histochemical methods. This study will be the first of a series with long-term ob

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  10. Abscription?-Based CpG Methylation Assays for Early Cancer Detection

    SBC: Ribomed Biotechnologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): This application is focused on the development of a simple and sensitive technology for the detection of CpG methylation in CpG islands of human cancer cells. CpG islands are short genomic segments in the promoter regio ns of most human genes that are enriched in the dinucleotide CpG. CpG islands are unmethylated in normal tissues but become progressively more ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
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