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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Recombinant Outer Membrane Vesicles as a Novel Adjuvant for a Malaria Vaccine

    SBC: VERSATOPE THERAPEUTICS, INC.            Topic: NIAID

    Plasmodium falciparum is the most fatal species of the malaria protozoan parasite infecting humansThe ability to control disease or outbreaks of Pfalciparum malaria with a vaccine has eluded investigators for decadesInnovative adjuvants for malaria vaccines are urgently needed to provide long lasting immune responses and high levels of inhibitory antibodiesWe propose to develop a novel malaria vac ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. SBIR Topic 104, Fast-track, Tapered Guidewires for Transcatheter Electrosurgery

    SBC: TRANSMURAL SYSTEMS LLC            Topic: NHLBI

    The goals are to develop and commercialize specific tools to simplify transcaval access to the aortaThe tools are a tapered guidewire and a connector switch to a common electrosurgery generatorThese will greatly simplify transcaval access proceduresreducing the required operator skillmaking the procedure more accessible to a wider array of patients and operatorsand reduce the cost of the procedure

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. SBIR TOPIC 096:Novel Biodegradable Stents for Neonatal Aortic Coarctation

    SBC: 480 Biomedical Inc.            Topic: NHLBI

    Aortic coarctation is a common congenital heart condition that is usually recognized during the neonatal period early after birth The usual treatment is open surgery Non surgical catheter based stent therapy is not available to treat neonatal aortic coarctation because children outgrow commercially available metallic stents Absorbable stents might revolutionize the treatment of aortic coarctation ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. SBIR Topic 103, Fast-track, Devices for Transcatheter Surgery

    SBC: TRANSMURAL SYSTEMS LLC            Topic: NHLBI

    The objective of this contract is to design a series of prototype transcatheter devices that will enable a wide range of novel transcatheter procedures for both adult and pediatric structural heart patientsThere is an unmet need for a suite of tools that will enable a wide range of novel but attainable non surgical interventional cardiovascular procedureswhich the contractor will develop and testT ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Development of “Permit Wizard” Software for AssistedPermit Application Completion

    SBC: Total Quality Systems, Inc.            Topic: 833

    TECHNICAL ABSTRACT: The objective of this project is to research the technical feasibility of designing a software tool “Permit Wizard” that will automate the process for aquamarine permit application submittal, review, approval/disapproval and issue (including collection of fees). Aquaculture producers are currently faced with slow, complex, and often confusing permitting processes that must ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  6. Riptide Hypoxic Zone AUV

    SBC: Riptide Autonomous Solutions, LLC            Topic: 827

    TECHNICAL ABSTRACT: Buoyancy driven oceanographic gliders, although reasonably cost effective, have challenges operating in the zones due to high gradients in water density. Under this topic, Riptide will provide a cost-effective autonomous undersea vehicle (AUV) design leveraged from Riptide's family of man-portable AUVs that can more effectively map the hypoxic areas. The stated goals of this to ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  7. Harmful Algal Bloom Species, Toxin and Total Phytoplankton Identification System (HABStats) for HandHeld, Remotely Networked or Submersible Operation

    SBC: CoastalOceanVision, Inc            Topic: 821

    TECHNICAL ABSTRACT: We propose to develop and commercialize the next generation of low cost, low power, ruggedized, and accurate phytoplankton single cell and whole colony counting, characterization and classification system called HABStats. We will accomplish this using the following three unique and innovative approaches: 1) High-throughput color, Light Field Imaging Flow Cytometry to acquire mo ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  8. Low-cost Mooring Location Beacon for Coastal Applications

    SBC: Triton Systems, Inc.            Topic: 825

    TECHNICAL ABSTRACT: Triton Systems, Inc. proposes development of the Open-Source Oceanographic Asset Recovery Beacon (OpenORB) that will allow the deployment of coastal instrumentation moorings with affordable protection against loss. This open-source kit would significantly reduce the purchase price of a commercial location beacon by allowing the end-user to assemble a customized system with mini ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  9. Developing a robust and scalable calibration approach to low-cost AQ sensing

    SBC: Aerodyne Research, Inc.            Topic: 813

    TECHNICAL ABSTRACT: Poor air quality represents a major public health risk, contributing to an estimated one of every eight deaths worldwide. Low-cost air quality sensors have developed rapidly over the last few years and offer the opportunity to make air quality monitoring inexpensive and widespread. However, low-cost sensors are currently unable to deliver accurate, reliable data due to a lack o ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  10. Automated peak fitting and analysis software for advanced gas chromatography and mass spectrometer systems

    SBC: Aerodyne Research, Inc.            Topic: 827

    TECHNICAL ABSTRACT: Recent advances in gas chromatographic (GC) and mass spectrometric (MS) techniques for atmospheric measurements have led to highly complex data sets that have overwhelmed the capabilities of current data analysis software. We propose a new method for the automated reduction of chromatographic data using peak-fitting algorithms. By relying upon constrained peak-fit parameterizat ...

    SBIR Phase II 2018 Department of CommerceNational Oceanic and Atmospheric Administration

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