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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. AutoRegister: A system for enhancing the accuracy of tumor change detection

    SBC: CORTICOMETRICS LLC            Topic: NCI

    DESCRIPTION (provided by applicant): This project proposes to build an integrated software-based system for enhancing the accuracy of tumor change detection. The intent of the system, called AutoRegister, which is to be deployed on a clinical magnetic resonance imaging (MRI) scanner platform, is to automate the alignment of a patient's brain scan with that of a prior scan, such that subseque ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Brain penetrant Hsp90 inhibitors for Alzheimer's disease

    SBC: YUMA THERAPEUTICS CORPORAITON            Topic: NIA

    DESCRIPTION provided by applicant Neurodegeneration in Alzheimerandapos s disease AD may result from deposition of A as plaques in brain tissue However less effort has been made to elucidate the role of tau containing neurofibrillary tangles NFTs in AD Accumulating evidence suggests that tau containing NFTs is an important component in the initiation and progression of AD and other neu ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Coils for Human Whole Body Imaging at 7T

    SBC: LIFE SERVICES L.L.C.            Topic: NIBIB

    DESCRIPTION provided by applicant For this Phase II STTR proposal the investigators plan to develop and commercialize the radiofrequency RF coil technology to make T body MRI possible and to translate this new technology to vastly improve T clinical MRI as well In the Phase I project leading to this proposal all specific aims were accomplished to demonstrate the feasibility of safely an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Commercial Methods for Production of Orientation Patterned GaAs

    SBC: PHYSICAL SCIENCES INC.            Topic: AF06T010

    The Air Force desires development of a commercial production source for nonlinear optical (NLO) gallium arsenide semiconductor crystals with orientation patterning, i.e., OP-GaAs. The Phase I project has demonstrated feasibility for a fabrication method of OP-GaAs which exclusively utilizes processes anticipated to be available from commercial vendors and at Physical Sciences Inc (PSI). Molecula ...

    STTR Phase II 2008 Department of DefenseAir Force
  5. Compact CMOS-Compatible Optical Transceiver

    SBC: PHYSICAL SCIENCES INC.            Topic: AF14AT13

    ABSTRACT: Close integration of photonic devices with silicon complementary metal-oxide semiconductor (CMOS) electronics can yield significant performance improvements in many applications. The recent development of novel integrated structures in silicon including waveguides, resonators, and photodetectors will enable dramatic reductions in size, weight, and power for components implementing compl ...

    STTR Phase I 2014 Department of DefenseAir Force
  6. Composite Transistor Array Vapor Sensor

    SBC: GINER INC            Topic: AF08T015

    The Giner, Inc. Phase I program will examine the response to explosive and toxic gas simulants of sensor arrays using a combination of specifically doped metal oxides (DMO) developed at Giner, Inc. in conjunction with metallophthalocyanine (MPc) thin films developed at the University of California at San Diego (UCSD). Electronic controls developed for the MPc sensors will be evaluated also for th ...

    STTR Phase I 2008 Department of DefenseAir Force
  7. Decision Making under Uncertainty for Dynamic Spectrum Access

    SBC: INFOBEYOND TECHNOLOGY LLC            Topic: AF13AT02

    ABSTRACT: Due to scarcity of spectrum, Dynamic Spectrum Access (DSA) becomes a needed technology to improve the utilization of electromagnetic spectrum for DoD satellite communication. However, current DSA approaches are developed for terrestrial communications without addressing the unique challenges for SATCOM environments such as error-prone spectrum sensing, high mobility, and large coverage. ...

    STTR Phase I 2014 Department of DefenseAir Force
  8. Delivery of Sleeping Beauty Transposons to Dog Liver for Gene Therapy

    SBC: DISCOVERY GENOMICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of Discovery Genomics, Inc. is to develop the Sleeping Beauty transposon system for human gene therapy. To achieve this to treat hemophilia, we must be able to direct uptake and long-term expression of therapeutic genes in targeted tissues such as the liver. Only one method of plasmid delivery has been effective for high-level gene expression ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  9. Detection of Biofilm Bacteria using GloBac

    SBC: SUBC, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The microbiologic diagnosis of infected joint anthroplasty is inaccurate using current techniques. Dr. Robin Patel has developed and validated a new technique that samples microorganisms in biofilms on the surface of ex planted orthopedic implants. This technique yields biofilm microorganisms suspended in solution; currently these organisms are detected using p ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  10. Developing Inhibitors of the STARS/SRF Pathway for Treatment of Type 2 Diabetes

    SBC: Jenesis Biosciences LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): Type 2 diabetes (T2D) has reached epidemic proportions in the United States, affecting an estimated 8.3% of the population. Unfortunately, the majority of individuals with diabetes continue to have suboptimal control ofglucose, therefore new and improved approaches to prevention and treatment are sorely needed. Dr. Mary Elizabeth Patti's laboratory at the ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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