Award Data

The primary market focus for the high end mass spectrometer industry is to fully characterize proteins and their post translational modificationsPTMswithin the biopharmaceutical industryThese analyses remain challenging despite major advances in the speedresolution and mass accuracy of modern mass spectrometersA key weakness with current instrumentation for protein characterization lies in the met ...

PROJECT SUMMARY Perinatal depressionexperienced by at leastof pregnant and postpartum womenis recognized as the most common complication of childbirth and as having extremely serious consequencesincluding significant suffering for pregnant women new mothers and their familiesand adverse impacts on infant developmentUnfortunatelythere are many barriers that make it difficult for women with perinata ...

This SBIR Fast Track application focuses on the development of a nanoconstruct for co delivery of siRNA and chemotherapy drugs to drug resistant human epidermal growth factor receptor typepositiveHERbreast cancerHERbreast cancer is a subtype that presents HERoverexpression and accounts forof invasive breast cancersHERbreast cancer has poor prognosis despite the rigorous current first line treatmen ...

Integrative approaches have been found to reduce suffering and improve quality of life in palliative carePCpopulationsand are increasingly in demand by patients and their familiesHoweverthere remains a lack of comprehensiveinterprofessionaleasily accessible continuing education continuing medical educationCE CMEon their evidence based use in PC contextsObjectiveThis FastTrack project will develop ...

Abstract Although an efficient prophylactic vaccine is available for hepatitis B virusHBVchronic hepatitis BCHBaffects up tomillion people worldwideand despite advances remains mostly incurableIn adultsacute HBV infection is cleared inof cases by CDT cell mediated mechanismsbut chroniclifelong infection ensues in the remaining individualswhich can lead to liver cirrhosis and cancerThe induction an ...

PROJECT SUMMARY ABSTRACT This Small Business Innovation Research Phase II project supports the development of a novel bioabsorbable surgical clip and applier for rapid closure of the dura mater in open and minimally invasive spine surgeryThe dura mater is the protective membrane that covers the brain and spinal cord and contains cerebrospinal fluidCSFOpenings in the duradurotomycan result in CSF l ...

This Phase II project builds upon previous research to demonstrate the technical merit, feasibility, and cost-effectiveness of combining commercially-available mobile devices and neural networks with cloud computing to further develop the WhenWear Advisor system to assist employees with intellectual disabilities (ID) to independently and successfully accomplish vocational tasks when provided with ...

AbstractSerious non variceal upper gastrointestinal bleedingNVUGIBis a major cause of morbidity and mortality worldwideIncidence of NVUGIB in the US is close toevents peradultswith approximatelyhospital admissions annuallyUS treatment and prevention of NVUGIB continues to be a major medical emergencycostingmillion dollars every yearFailure in standard of care for NVUGIB results in mortality rates ...

DESCRIPTION (provided by applicant): The overall goal of the proposed SBIR program is to implement and evaluate a low cost retinal camera, the Laser Scanning Digital Camera (LSDC), in a system for diabetic retinopathy (DR) screening. Untreated DR has reached epidemic levels in underserved populations worldwide. As the LSDC has already demonstrated its readiness for DR screening in preliminary stud ...

DESCRIPTION (provided by applicant): Today, arsenic (As) poisoning is one of the major environmental threats worldwide as millions of human beings have been exposed to excessive arsenic through contaminated drinking water. The serious toxicity of arsenic has been well documented. Worldwide, communities demand novel separation technologies for the removal of arsenic from drinking water. Conventiona ...