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SBC: PATHOVACS INCORPORATED Topic: CBD18A001
The focus of this STTR phase I component is on proof-of-concept studies demonstrating applicability of technical approaches for identificationof circulatory diagnostic markers for infectious disease. Therefore, the primary objective of this project is to determine feasibility of one suchtechnical approach called Proteomics-based Expression Library Screening (PELS), for identification of pathogen-d ...STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
SBC: MAPP BIOPHARMACEUTICAL, INC. Topic: CBD18A002
There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terriblemorbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditionalvaccines have proven to be a huge contribution to public health, they do have some limitations especially in the cont ...STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
SBC: Luna Innovations Incorporated Topic: CBD18A002
Marburg virus (MARV) is a filamentous enveloped non-segmented negative sense RNA virus. This viruse is considered to be extremelydangerous with case fatality rates as high as 88-90%. Extensive efforts have gone towards effective vaccines for MARV prevention, however,none have been successfully established as licensed vaccines. Glycoprotein (GP) is the only surface protein of MARV. There are substa ...STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
SBC: Euler Scientific Topic: NGA20A001
Deep Neural Networks have become ubiquitous in the modern analysis of voluminous datasets with geometric symmetries. In the field of Particle Physics, experiments such as DUNE require the detection of particle signatures interacting within the detector, with analyses of over a billion 3D event images per channel each year; with typical setups containing over 150,000 different channels. In an ...STTR Phase I 2020 Department of DefenseNational Geospatial-Intelligence Agency
SBC: Clear Scientific, LLC Topic: CBD20AT001
Opioids, especially synthetic opioids, are a constant threat to the safety of civilian first responders; there are now serious concerns about their use in modern chemical warfare. Fentanyl and its many analogues (carfentanil, remifentanil, lofentanil, mefentanil, sufentanil, etc.) are extremely hazardous—if ingested or inhaled, many synthetic opioids cause lethal intoxication with only a few gra ...STTR Phase I 2021 Department of DefenseOffice for Chemical and Biological Defense
SBC: TRITON SYSTEMS, INC. Topic: CBD20AT001
Triton Systems, Inc. will collaborate with The University of Massachusetts Lowell to develop a spray-based technology for the rapid, visual identification of opioids, turning contaminated areas from nondescript white powders to a brightly colored spots for easy recognition with the naked eye. The technology leverages molecular recognition units that bind strongly and specifically to a variety of o ...STTR Phase I 2021 Department of DefenseOffice for Chemical and Biological Defense
SBC: PROGRAMS MANAGEMENT ANALYTICS & TECHNOLOGIES INC Topic: SOCOM22DST01
Multi-Dimensional Event Sourcing & Correlation - Publicly Available Information (PAI) (MDESC-P) will support collection jointly across disparate PAI sources with coordinated cueing of more constrained intelligence, surveillance, target acquisition, and reconnaissance (ISTAR) sources. The primary objective for MDESC-P is to deliver a scalable and automated PAI collection management solution using a ...STTR Phase I 2022 Department of DefenseSpecial Operations Command
SBC: OPTO-KNOWLEDGE SYSTEMS INC Topic: SOCOM21C001
The US requires standoff precision strike capabilities in GPS-denied and high threat environments. This includes fire-and-forget lock-after-launch vision-based guidance for SOPGM. Due to emerging threats, a paradigm shift is occurring in the way we gather intelligence, maintain surveillance, and perform reconnaissance. ISR platforms are evolving, and artificial intelligence is at the forefront of ...STTR Phase I 2022 Department of DefenseSpecial Operations Command
SBC: CHARLES RIVER ANALYTICS, INC. Topic: SOCOM21C001
Precision-guided munitions have demonstrated dramatic effects with minimal collateral damage. New technology developed specifically to deny them accurate guidance information is now feasible, even for non-traditional adversaries. Further, digital communications are flooding the air with signals that interfere with communications many guidance methods rely on. Swarms of small, covert small Uncrewed ...STTR Phase I 2022 Department of DefenseSpecial Operations Command
SBC: INTELLIGENT OPTICAL SYSTEMS INC Topic: CBD20AT001
Intelligent Optical Systems, Inc., in collaboration with Bowling Green State University, proposes to develop a field-rugged, eye-readable indicating spray solution that can immediately detect synthetic opioids over a large area of contamination (i.e., military vehicles, individual protective equipment, clandestine labs, etc.). The proposed chemosensor in a spray solution format will detect multipl ...STTR Phase I 2021 Department of DefenseOffice for Chemical and Biological Defense