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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. NOVEL MARKERS FOR PROSTATE CANCER DIAGNOSIS/PROGNOSIS

    SBC: CORIXA CORPORATION            Topic: N/A

    This proposal discusses the development Real-time PCR assays using novel prostate cancer markers for the diagnosis/prognosis of prostate cancer. Prostate cancer is a leading cause of deaths among men in the U.S. Good prognosis depends on the early detection of the disease. However, the sensitivity and the specificity of the current available diagnostic markers is insufficient. Using state of t ...

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  2. Proof-of-Concept for Card-based CD4 Cell Counting

    SBC: E.I. SPECTRA, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of this proposed research is to develop a simple, inexpensive point-of-care device that will perform absolute and percent CD4+ T cell counts from whole blood. This will be accomplished by adaptin g and testing a novel hybrid approach to microfluidic sample preparation and analysis. One-time use thin-film laminated microfluidic cassette ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  3. CELL PERMEANT PHOSPHOINOSITIDES

    SBC: ECHELON BIOSCIENCES, INC.            Topic: N/A

    N/A

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  4. ULTRASOUND MEDIATED PERMEABILITY-DRUG DELIVERY

    SBC: EKOS CORPORATION            Topic: N/A

    DESCRIPTION (Verbatim from Applicant's Abstract): The goal of this project is to demonstrate the feasibility of using ultrasound to temporarily make vascular tissue and cell membranes more permeable to deliver drug to vessel walls. EKOS has developed an ultrasound-catheter device for transmural drug delivery that may be useful in the treatment of restenosis following ballo ...

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  5. Crystallization Tools for Structural Genomics

    SBC: EMERALD BIOSTRUCTURES,INC.            Topic: N/A

    DESCCRIPTION: Applicant?s abstract) An integrated, automated protein crystallization system,RoboHTC (Robotic High-Throughput Crystallization), will be developed, consisting of software and hardware tools suitable for large-scale protein crystallography projects, such as structural genomics. These tools will also be highly modular, allowing individual home laboratories to use one or more components ...

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  6. Anti-Cancer Drug Design Targeting Human Topoisomerase I

    SBC: EMERALD BIOSTRUCTURES,INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Human topoisomerase I (topo I) is the sole intracellular target of camptothecin (CPT) and other "topo I poisons," some of which are among the most promising anticancer drugs ever identified. Emerald BioStructures, Inc. has successfully completed a Phase I SBIR research program that sought to elucidate the X-ray crystal structure of huma ...

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  7. System for generation of frozen-hydrated samples using the Focused Ion Beam

    SBC: HUMMINGBIRD PRECISION MACHINE CO.            Topic: N/A

    Project Summary The long term objective of our application is to develop hardware and procedures that will allow researchers to better understand the function of the cell. Our specific aim is to provide a system that will allow researches to better prepare frozen hydrated specimens for study via tomographic reconstruction in the transmission electron microscope(TEM) Current methods of preparing f ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  8. New Generation Test for Visceral Leishmaniasis Diagnosis

    SBC: Inbios International Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Visceral leishmaniasis (VL) is a disease with high mortality in both developed and developing countries. The causative agents are the parasites Leishmania chagasi, donovani and infantum depending on geographic location. In Mediterranean countries, co-infection with HIV has become problematic and asymptomatic individuals have been sh ...

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  9. Statistical Software for Data with Measurement Error

    SBC: INSIGHTFUL CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The ultimate objective of this research application is the development of S+ME: a next generation software for handling covariate measurement error. The developed methodologies are also applicable to data with missing covariates. To achieve this, much of our research effort will be devoted towards combinging algorithms in regression calib ...

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  10. Bayesian Textual and Multimedia Information Retrieval

    SBC: INSIGHTFUL CORPORATION            Topic: N/A

    N/A

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
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