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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Breast Cancer Locator

    SBC: CairnSurgical, Inc.            Topic: 101

    PROJECT SUMMARY ABSTRACT CairnSurgical LLC a Dartmouth spin off company will optimize and test the feasibility of a new image guided intervention device the Breast Cancer Locator BCL in breast conserving surgery BCS to i eliminate wire localization a moderately effective somewhat costly and certainly inconvenient procedure for patients and concomitantly to ii reduce positive ma ...

    SBIR Phase I 2016 Department of Health and Human Services
  2. Precision Quality Check of Immunotherapeutics via Single Cell Cytokine Mapping

    SBC: IsoPlexis            Topic: 102

    Despite the demonstrated benefit of CD targeted CAR T immunotherapeutics two challenges remain to bringing the therapeutics to market The first key challenge is to reproducibly manufacture the therapy so that the cellsandapos cytokine mediated function acts in a predictably consistent fashion post manufacturing The second key challenge is to manage the cellandapos s adverse effect immuno to ...

    SBIR Phase I 2016 Department of Health and Human Services
  3. Point of care immunoassay for rapid diagnosis of tinea capitis

    SBC: DxDiscovery Incorporated            Topic: NIBIB

    Tinea capitis scalp ringworm is a fungal dermatophyte infection of scalp hair follicles that afflicts of the U S pediatric population Tinea capitis is a major health care disparity because it occurs predominantly among individuals with a disadvantaged socioeconomic background and sub Saharan African descent Diagnosis of tinea capitis is currently dependent on culture and microscopy Both ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Stabilized Prasugrel enantiomers for pediatric sickle cell disease

    SBC: DeuteRx LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Sickle cell disease SCD is a severe inherited disease that occurs in about in newborns in the U S greater than that of any other condition detected by newborn blood screening Only one treatment hydroxyurea is approved for the complications of SCD in adult patients Hydroxyurea is not approved in children due to concerns regarding possible genotoxi ...

    SBIR Phase I 2016 Department of Health and Human Services
  5. Adaptable Pediatric Neurocognitive Assessment

    SBC: CREARE LLC            Topic: NICHD

    DESCRIPTION provided by applicant Millions of children around the globe are afflicted with conditions that can alter neuropsychological development including human immunodeficiency virus HIV traumatic brain injury TBI cerebral malaria and a host of other developmental and acquired diseases and disorders Early assessment and intervention are critical in overcoming cognitive and deve ...

    SBIR Phase I 2016 Department of Health and Human Services
  6. Enhancing Quality of Life for Disabled Patients via High Humidified Flow

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: NA

    The goal of this project is to develop a lightweight and compact system that provides 51 percent oxygen enriched air at four to six liters per minute equivalent pure oxygen to individuals with chronic obstructive pulmonary disease (COPD). Existing systems may not deliver a high-enough supply of oxygen to support these individuals who may be capable of activity and for whom increased activity would ...

    SBIR Phase I 2016 Department of Health and Human Services
  7. IGF OT IGF NEUROPSYCHOLOGICAL ASSESSMENT SYSTEM FOR CANCER PATIENTS

    SBC: CREARE LLC            Topic: NCI

    Decline in cognitive ability is a major quality of life problem for many cancer survivors This problem is affected bywhich treatments a particular individual receives Unfortunately research has provided little guidance on whichtreatment may be best for an individual based on unfavorable cognitive side effects To help researchers fill thisinformation gap and provide doctors and patients with t ...

    SBIR Phase I 2016 Department of Health and Human Services
  8. Isocyanate-Free Polyurethane Resins for One-Component, Ambient-Cure Coatings

    SBC: RENUVIX LLC            Topic: 15NCER04

    Due to their exceptional properties, polyurethane coatings are used extensively in our society.Unfortunately, the socyanate-functional components used in the curing of polyurethanes are generally toxic. Thus, there is a need for polyurethane resins that can be cured without the use of isocyanate-functional components. In addition to enabling the production of polyurethane coatings that are free ...

    SBIR Phase I 2016 Environmental Protection Agency
  9. A High Efficiency Cryocooler for In-Space Cryogenic Propellant Storage

    SBC: CREARE LLC            Topic: H204

    NASA is considering multiple missions involving long-term cryogen storage in space. Liquid hydrogen and liquid oxygen are the typical cryogens as they provide the highest specific impulse of practical chemical propellants. These cryogens are stored at temperatures of nominally 20 K for hydrogen and 90 K for oxygen. Due to the large size of these tanks, refrigeration loads to maintain zero-boil- ...

    SBIR Phase I 2016 National Aeronautics and Space Administration
  10. Closed-Loop, Non-Venting Thermal Control for Mars EVA Suits

    SBC: CREARE LLC            Topic: Z201

    NASA seeks new thermal control technology for EVA suits on Mars. The system must be closed-loop and non-venting, have negligible impact on the Martian environment, and be capable of operating under Mars surface conditions. We propose to develop a space evaporator/absorber/radiator (SEAR) system with innovative features that will enable operation on Mars. The system uses a regenerable water abso ...

    SBIR Phase I 2016 National Aeronautics and Space Administration

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