Award Data

DESCRIPTION (provided by applicant): If left undetected and untreated, reduced vision in one eye can lead to monocular blindness in an amblyopic eye. Most vision screening is conducted on children once they have started kindergarten; this is after the critical detection period for the treatment of amblyopia. Early detection is essential for favorable prognosis. Unfortunately less than 21% of pre-k ...

DESCRIPTION (provided by applicant): The goal of the present work is to demonstrate a label-free multiplexed immunoassay platform liver disease diagnosis. The method is to integrate multiple tests for serum antigens and antibodies onto a single disposable chip that could be used with the instrument for about the cost of one or a few current immunoassays that identify the presence of just one marke ...

DESCRIPTION (provided by applicant): We propose the development of a single-chip, multiplexed, label-free platform for Alzheimer's disease diagnosis and monitoring of protein markers in the cerebral spinal fluid (CSF). The Spectral Reflectance Imaging Biosensor is a label-free protein array technology that can monitor real-time binding label-free at more than 1000 locations simultaneously. A uniq ...

We propose to research, design, and evaluate the feasibility of a Visualization for Integrated Cyber Command and Control (VIC3) system that fuses and displays vast amounts of multidimensional cyber security data from multiple sources to provide a unified view of the cyber battlespace. VIC3 will allow commanders to monitor cyber activity, correlate events, understand information dependencies, evalu ...

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Technology Transfer Phase I project is for the development of ultrahigh thermal conductivity carbon fiber for use in graphite-metal composites. The use of graphite fiber in a metal matrix produces a composite with high thermal conductivity and controlled CTE, the two key requirem ...

DESCRIPTION (provided by applicant): The main objective of this project is to develop a new therapeutic to improve the outcome for patients with intermediate-risk prostate cancer. The indication is a first-line adjuvant to be combined with radiation therapy for prostate cancer. The desired outcomes are improved local control rate, decreased recurrence and improved disease-free survival. This grant ...

The drumbeat for higher efficiency gas turbine engines is driving new designs capable of operating at higher temperatures and pressure ratios, in fewer stages, and with higher airfoil loads.   These conditions pose a great challenge for turbomachinery designers.  They must now accurately predict airfoil metal temperatures to design effective cooling schemes that counter the high external gas te ...

Ammonia has an important role in the chemistry of the atmospheric environment and air quality. Ammonia emissions are a major environmental concern, yet they remain poorly quantified. There is a need for a sensitive ammonia instrument to monitor emissions and evaluate their effects on local and regional environments. An instrument capable of continuous monitoring is required to understand diurna ...

Carbon dioxide is monitored worldwide at hundreds of monitoring stations. However, existing methods rely on the use of high pressure calibration gas cylinders, which are both labor intensive and expensive. Thus, there is a pressing need for an affordable, highly accurate (at least 1 part in 3000) carbon dioxide monitor for the ambient atmosphere that can operate unattended for several months or ...

We propose to design, construct and test a first implementation of a non-dispersive technique for the measurement of atomic absorption in the plumes of liquid rocket engines in altitude test facilities. Led by NASA Stennis Space Center (SSC), the observation of metal atom emission from liquid rocket engine exhausts at sea level conditions has become a highly successful health monitoring technique ...