List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. LASER FOR SELECTIVE PHOTOTHERMOATHEROLYSIS

    SBC: CANDELA CORPORATION            Topic: N/A

    CARDIOVASCULAR DISEASE IS THE LEADING CAUSE OF DEATHS IN THEUNITED STATES, CLAIMING NEARLY TWICE AS MANY LIVES AS CANCER. LASER ANGIOPLASTY HAS IMMENSE APPEAL, BUT A RELIABLE, PREDICTABLE SYSTEM HAS NOT YET BEEN DEVELOPED. RESEARCHERS HAVE CONDUCTED PRELIMINARY STUDIES TO DEMONSTRA-TE PREFERENTIAL ABSORPTION OF DYE LASER ENERGY BY ANTHERO- MATOUS PLAQUES WITH MINIMAL ABSORPTION BY NORMAL ARTERIAL ...

    SBIR Phase II 1988 Department of Health and Human Services
  2. TELEPHONE COMMUNICATION FOR THE DEAF

    SBC: Duffy Engineering            Topic: N/A

    THIS PROPOSAL ADDRESSES THE PROBLEM OF TELEPHONE COMMUNICATION BY THE DEAF AND DEAF-BLIND. THE CURRENT STATE OF THE ART ALLOWS THESE PERSONS TO COMMUNICATE ON THE TELEPHONE WITH OTHERS WHEN BOTH ARE USING SPECIALIZED EQUIPMENT. THE PROPOSED CONCEPT WOULD REQUIRE SPECIALIZED EQUIPMENT BY THE HEARING-IMPAIRED PERSON ONLY. THE PROCESS IS BASED ON A COMMERCIAL MICROCOMPUTER CONVERTING TONE OR PULSE SI ...

    SBIR Phase II 1988 Department of Health and Human Services
  3. GENETIC ENGINEERING OF AN IMPROVED FACTOR VIII PRODUCT

    SBC: Genetics Institute Inc.            Topic: N/A

    FACTOR VIII IS THE PLASMA PROTEIN THAT IS FUNCTIONALLY DEFICIENT IN HEMOPHILIA A PATIENTS, RESULTING IN THE CLINICAL BLEEDING DISORDER. PATIENTS WITH THIS DISEASE REQUIRE FREQUENT INFUSIONS OF FACTOR VIII IN ORDER TO MAIN- TAIN HEMOSTASIS, PARTICULARLY DURING SURGERY OR FOLLOWING PHYSICAL TRAUMA. PRESENTLY, THE COMMERCIAL FACTOR VIII PRODUCT IS PURIFIED FROM POOLED BLOOD PLASMA OBTAINED FROM HUMAN ...

    SBIR Phase II 1988 Department of Health and Human Services
  4. RAPID DIAGNOSTIC TEST FOR HUMAN FUNGAL PATHOGENS

    SBC: Integrated Genetics Inc            Topic: N/A

    LOCALIZED AND SYSTEMIC MYCOSES CAUSED BY PATHOGENIC FUNGI (E.G., THE YEASTS CANDIDA ALBICANS AND CRYPTOCOCCUS NEOFORMANS) REPRESENT A SERIOUS HEALTH THREAT, ESPECIALLY TOIMMUNOCOMPROMISED PATIENTS AMONG WHOM INVASIVE CANDIDIASIS HAS HIGH MORBIDITY AND MORTALITY. CURRENTLY, IDENTIFICATIONOF FUNGAL PATHOGENS REQUIRES ISOLATION OF PURE CULTURES, FOLLOWED BY TESTING FOR SUBSTRATE ASSIMILATION AND FERM ...

    SBIR Phase II 1988 Department of Health and Human Services
  5. MULTIDRUG-RESISTANCE PATTERSN IN HUMAN TUMOR CELLS

    SBC: Integrated Genetics Inc            Topic: N/A

    NEW ANTITUMOR COMPOUNDS IDENTIFIED IN SCREENING PROGRAMS AREFREQUENTLY INEFFECTIVE AGAINST METASTATIC HUMAN TUMORS THAT EXHIBIT MULTIPLE-DRUG RESISTANCE. TO ENHANCE THE EFFICIENCYOF SCREENING FOR AGENTS LIKELY TO BE EFFECTIVE IN THE TREATMENT OF SUCH TUMORS, INTEGRATED GENETICS, INC. PROPOSESTO DEVELOP A DIAGNOSTIC PRODUCT CONSISTING OF A PANEL OF WELL-CHARACTERIZED, MULTIDRUG-RESISTANT DERIVATIVE ...

    SBIR Phase II 1988 Department of Health and Human Services
  6. AN EXTRACORPOREAL PULSATILE ASSIST DEVICE (EPAD)

    SBC: WHALEN BIOMEDICAL, INC            Topic: N/A

    THE OBJECTIVE OF THIS PROGRAM IS THE DEVELOPMENT OF AN EXTRACORPOREAL PULSATILE ASSIST DEVICE (EPAD), A VALVELESS DIASTOLIC AUGMENTATION PUMP WITH VARIABLE STROKE VOLUMES UP TO 80 ML PER BEAT. THE EPAD IS DESIGNED AS A LOW-COST, DISPOSABLE DEVICE WHOSE INITIAL APPLICATION WILL BE AS A TEMPORARY RIGHT VENTRICULAR ASSIST DEVICE IN CONJUNCTION WITH THE USE OF A LEFT VENTRICULAR ASSIST DEVICE (LVAD) F ...

    SBIR Phase II 1988 Department of Health and Human Services
  7. NOVEL PROPORTIONAL PROXIMITY SENSOR FOR AUTONOMOUS, SPACE BASED ROBOTS

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    ROBOTICS IS BECOMING AN INCREASINGLY IMPORTANT FIELD IN RESEARCH AND MANUFACTURING. MOST ROBOTS, HOWEVER, EITHER PERFORM REPETITIVE PREPROGRAMMED OPERATIONS OR ARE GUIDED BY A HUMAN OPERATOR. THIS IS NOT PRACTICAL IN MANY APPLICATIONS WHERE AUTONOMOUS OPERATION IS REQUIRED, AND THE MOST IMPORTANT IMPROVEMENTS IN FUTURE GENERATIONS OF ROBOTS, ESPECIALLY FOR SPACE APPLICATIONS, WILL COME IN THE AREA ...

    SBIR Phase II 1988 National Aeronautics and Space Administration
  8. DUAL FUNCTION PEROVSKITE CATALYSTS & SUPPORTS FOR ALKALINE REGENERATIVE & PRESSURIZED FUEL CELLS

    SBC: Physical Sciences Inc.            Topic: N/A

    DURING OUR PHASE I PROGRAM, WE DEMONSTRATED A NOVEL APPROACHFOR INCREASING THE SURFACE AREAS OF MIXED METAL OXIDES OBTAINED FROM COMMERCIAL SOURCES. IN THE CASE OF LACO03, WEOBTAINED A SEVEN-FOLD INCREASE IN SURFACE AREA USING OUR NOVEL TECHNIQUE AND DEMONSTRATED THE MAINTENANCE OF THE PARENT PEROVSKITE STRUCTURE USING POWDER X-RAY DIFFRACTION. ADDITIONALLY, WE CONFIRMED AN INCREASE IN OXYGEN REDU ...

    SBIR Phase II 1988 National Aeronautics and Space Administration
  9. A BORON ASSISTED COMBUSTION MODEL WITH SENSITIVITY ANALYSIS DEVELOPMENT

    SBC: Aerodyne Research, Inc.            Topic: N/A

    SOLID BORON HAS LONG BEEN RECOGNIZED AS A POTENTIAL HIGH VOLUMETRIC DENSITY PROPELLANT FOR VOLUME LIMITED ROCKET AND AIR BREATHING PROPULSION SYSTEMS. HOWEVER, ACHIEVING THIS POTENTIAL HAS BEEN DIFFICULT DUE TO LOW COMBUSTION AND HEAT RELEASE EFFICIENCIES IN CONVENTIONALLY DESIGNED COMBUSTORS. A THREE PHASE MODEL OF BORON ASSISTED COMBUSTION IS POSTULATED AND THE ROLE THAT KINETIC SENSITIVITY ANAL ...

    SBIR Phase II 1988 Department of DefenseAir Force
  10. DEVELOPMENT OF SUBMARINE STRUCTURAL VIBRATION TRANSMISSION MODEL

    SBC: Atlantic Applied Research Corp            Topic: N/A

    THE ACTIVE SONARS TYPICALLY USED ON SUBMARINES OPERATE AT FREQUENCIES HIGH ENOUGH TO BE DIFFICULT IF NOT PRESENTLY IMPOSSIBLE TO MODEL ACCURATELY WITH FINITE ELEMENT ANALYSIS. LIKEWISE BEAM AND CYLINDER MODELS PROVIDE INADEQUATE REPRESENTATIONS OF THE HIGH FREQUENCY BEHAVIOR OF PLATE AND FRAME VIBRATIONS. THE APPLICATION OF THE AARC STATISTICAL ENERGY ANALYSIS PROGRAM WHICH INCLUDES BENDING, LONGI ...

    SBIR Phase II 1988 Department of DefenseNavy

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government