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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Clinical System for Measurement of Oral Crest Height Change in Dental Radiographs
SBC: Imagination Software Corporation Topic: NIDCRDESCRIPTION (provided by applicant): Twenty-six percent of the population twenty years and over have destructive periodontal disease (gt 4 mm loss of bone height). Alveolar bone height correlates well with subsequent tooth loss. Moreover, it has been foundthat periodontal disease correlates with other diseases, e.g., atherosclerosis and diabetes. Proper diagnosis, treatment, maintenance, and patie ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
Repair of Bone Defects with Human Autologous Pluripotent Very Small Embryonic lik
SBC: Caladrius Biosciences Topic: NIDCRDESCRIPTION (provided by applicant): Bone loss due to fractures and disease is a serious medical condition in the US affecting millions of Americans. It is particularly a problem with oral craniofacial disorders were the costs of treating damage exceeds60 billion annually. Furthermore, periodontitis is associated with systemic disorders such as diabetes mellitus, preterm low birth weight, and car ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
EpiVax Phase II SBIR: Preclinical studies of Tregitope Delivery and Mechanism of
SBC: EPIVAX, INC. Topic: NIDDKDESCRIPTION (provided by applicant): The goal of this Phase II project is to advance the development of novel tolerance-inducing peptides (Tregitopes) to prevent and/or treat Type 1 diabetes (T1D) by optimizing the clinical delivery vehicle and treatment protocol, and by identifying correlates of efficacy in preparation for Phase 1 clinical trials. More than 13,000 children in the U.S. are diagnos ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
Antifibrotic Therapy for Chronic Kidney Disease
SBC: Angion Biomedica Corp. Topic: NIDDKDESCRIPTION (provided by applicant): Chronic kidney disease (CKD) remains an unsolved challenge for the nephrologist, as it almost inevitably leads to end-stage renal failure, a life-threatening condition that necessitates renal replacement therapy. Few, if any, of the currently practiced therapeutic strategies oppose the molecular and cellular program of fibrosis that drives renal disease. There ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
Gene transfer to treat urinary urgency frequency nocturia and incontinence
SBC: Ion Channel Innovations, LLC Topic: NIDDKDESCRIPTION (provided by applicant): This grant application is initiated by Ion Channel Innovations, LLC., (ICI) an early stage biotechnology company that has completed the first, and only, phase I safety trial using plasmid DNA transfer with a non-specific gene MaxiK potassium channel promoter to treat urinary urgency, frequency, nocturia, and incontinence also known as overactive bladder or OAB ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
New In Vitro Human Liver Toxicity Bioassay System
SBC: Vivo Biosciences Inc Topic: NIEHSDESCRIPTION (provided by applicant): The overall objective of this SBIR proposal is to develop and commercialize a human 3D or mini- liver bioassay system suitable for real-time analysis of metabolic functions and long-term drug toxicity profiles. At present, liver functions are mostly studied using HepG2 cell line and primary hepatocytes cultured onto collagen or polymer matrices. However, these ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
Compact, cost-effective, and operator-friendly fundus camera for early detection
SBC: LUMETRICS, INC. Topic: NEIDESCRIPTION (provided by applicant): This SBIR application will revolutionize the methodology for routine examination of the back of the eye by developing an easy-to-use, pocket-sized, inexpensive digital camera for documenting retinal and optic nerve diseases. In order to reduce rates of preventable vision loss, the early diagnosis of treatable eye diseases has become increasingly important, espe ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
A novel physiologically realistic microfluidic in-vitro blood-brain barrier model
SBC: CFD RESEARCH CORPORATION Topic: NIGMSDESCRIPTION (provided by applicant): The overall objective of this study is to develop a novel in vitro microfluidic platform to test a drug or delivery vehicle's ability to permeate the Blood-Brain Barrier (BBB). In contrast to current in-vitro models, our proposed device, SIM-BBB, comprises of a microfluidic two-compartment chamber. The chamber is designed in such a way as to permit vis ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
Photoactivated Antimicrobial Collagen
SBC: CONVERSION ENERGY ENTERPRISES Topic: NIGMSDESCRIPTION (provided by applicant): The significance of this project is the development of a novel photoactivated collagen dressing with demonstrated bactericidal effects, minimal toxic effects and low susceptibility to mechanisms of microbial resistancein an effort to ultimately expand the armamentarium of antimicrobial agents for the management of wound infections. Approximately 2 million patie ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
Feasibility of Supercritical Carbon Dioxide Sterilization for Absorbable Suture M
SBC: NOVASTERILIS, INC. Topic: NIGMSDESCRIPTION (provided by applicant): Over the past several decades there has been relatively little innovation in the arena of medical device sterilization. Ethylene oxide (ETO) and gamma irradiation ( irradiation) are the only technologies commerciallyavailable for medical devices. In particular, synthetic polymeric medical devices are sterilized almost exclusively by ETO due to undesirable che ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health