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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Jerry the Bear: A Robotic Platform for At-Home Therapy and Education for Children with Type 1 Diabetes

    SBC: Sproutel            Topic: 200

    DESCRIPTION provided by applicant The goal of this SBIR Phase I application from Sproutel is to develop a curriculum for providing expert educational content on diabetes self management to be delivered via principles of game based learning in an appealing teddy bear robotic character designed for young children diagnosed with type diabetes mellitus Type diabetes T D affects approximately ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a Non adjuvanted VLP Vaccine against Stealth H N Influenza

    SBC: EPIVAX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Point of care immunoassay for rapid diagnosis of tinea capitis

    SBC: DxDiscovery Incorporated            Topic: NIBIB

    Tinea capitis scalp ringworm is a fungal dermatophyte infection of scalp hair follicles that afflicts of the U S pediatric population Tinea capitis is a major health care disparity because it occurs predominantly among individuals with a disadvantaged socioeconomic background and sub Saharan African descent Diagnosis of tinea capitis is currently dependent on culture and microscopy Both ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Developing Testing and Validating a Wearable Alcohol Biosensor

    SBC: Clinitech, LLC            Topic: 450

    PROJECT SUMMARY This application for a Phase I SBIR award represents a collaboration between Clinitech LLC and McLean Hospital Harvard Medical School to develop a wearable biosensor for detecting alcohol in the interstitial fluid of humans who have consumed alcohol Excessive use of alcohol accounts for much of the public health burden related to alcohol use disorders including fetal ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Noninvasive Functional Cortical Mapping with Innovative tEEG

    SBC: CREmedical Corp            Topic: 106

    PROJECT SUMMARY Resective neurosurgery is essential for treating a range of neurologic conditions such as epilepsy and brain tumorsFor some patientswhose lesion is close to cortical language areaspostoperative expressive or receptive language deficit is a major and feared postoperative complicationMuch effort is devoted to identifying the cortical language regionsand relating such localization to ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. A multivalent, easy-to-use product to mitigate and treat radiation exposure

    SBC: FIBROPLATE, INC            Topic: NIAID

    ABSTRACTThe threat of radiological and nuclear accidents or attacks demands for effective radiation medical countermeasuresMCMable to mitigate and treat the effects of exposure to ionizing radiationsHematopoietic acute radiation syndromeHRASand cutaneous radiation syndromeCRSpose severelife threatening risks to exposed individualsCurrently no effective radio mitigatorto be administered after radia ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. GAA-ITEM: Personalizing the Prediction of Anti-therapeutic Antibody Response in Pompe Disease Patients

    SBC: EPIVAX, INC.            Topic: 999

    Abstract SignificanceInfantile Pompe DiseaseIPDis an autosomal recessive glycogen storage disorder caused by a deficiency of acid alpha glucosidaseGAAleading to accumulation of glycogen in lysosomesprimarily in skeletalcardiac and smooth musclesUntreated IPD infants die within the firstyears of lifeEnzyme replacement therapyERTwith recombinant human GAArhGAAimproves survival and quality of lifebut ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Evidence-Based Pain Intervention for Veterans: Leveraging Mobile & Social Media

    SBC: Pro-Change Behavior Systems Inc            Topic: NCCIH

    Chronic musculoskeletal pain creates a significant public health burdenand Veterans are disproportionately affectedThe frequency and extent of co occurrence of pain and PTSDpain and Traumatic Brain InjuryTBIall three conditionsPost deployment Multi symptom DisorderPMDand other multi symptom syndromes can complicate and reduce the effectiveness of pain treatmentFurthermorethe majority of Veterans d ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Immunoassay for early diagnosis of mucormycosis

    SBC: DxDiscovery Incorporated            Topic: NIAID

    Mucormycosis is one of the deadliest of the invasive fungal infectionsMucormycosis occurs most often in patients with hematological malignancies undergoing chemotherapypatients who have received hematopoietic stem cell transplants or patients with diabetes mellitusImproved diagnosis is the most frequently noted unmet need for management of the mucormycosis patientDelays in treatment increase the m ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health

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