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Development of a long-acting, injectable controlled release butyrylcholinesterase formulation using predictive modeling.SBC: Qrono, Inc. Topic: CBD13107
Elevated levels of human butyrylcholinesterase (BuChE) confer protection from chemical warfare nerve agents and other organophosphorous chemicals. As a prophylactic, the key to enabling this protection is the ability to maintain elevated concentrations of BuChE in the plasma for days or weeks. Thus far, plasma-derived and PEGylated recombinant forms of BuChE have been tested in humans. However, ...SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
SBC: NANOGRIPTECH Topic: CBD13109
Hook and loop closures in Army uniforms have been identified as the critical sources of leaks in protective clothing/equipment, which limits the overall protective capability of the ensemble. New closure systems capable of providing both the shear and peel strengths demonstrated by hook and loop systems as well as hermetic sealing against any vapor permeation across the closure need to be develope ...SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
SBC: PCP TACTICAL, LLC Topic: SOCOM13005
PCP Ammunition Company will deliver a family of Lightweight Advanced Polymer Sub-Sonic Ammunition. We will do this by adapting our current family of calibers by decreasing the internal volume and shape of the case to match the optimal performance requirements of the cartridges. This will result in a sub-sonic ammunition that is lightweight, clean burning (due to the internal volume and dimension ...SBIR Phase I 2013 Department of DefenseSpecial Operations Command
SBC: PCP TACTICAL, LLC Topic: SOCOM13006
PCP Ammunition Company will research the design and development of Lightweight .50 caliber precision ammunition under this SBIR Phase I contract. PCP will concentrate our efforts on several separate criteria in order to improve upon the current .50 caliber round by utilizing PCP"s current lightweight polymer .50 caliber case. First, we will compare the performance of the current round agains ...SBIR Phase I 2013 Department of DefenseSpecial Operations Command
SBC: DRS SCIENTIFIC, INC. Topic: CBD13104
DRS Scientific proposes a new type of Acousto-Optic Tuned Filter (AOTF) polarimetric hyperspectral imager that is compact, rugged, and inexpensive, has no moving parts, is free of optical aberrations, and is fast and sensitive. It will cover 8-12 mm with 8 cm-1 spectral resolution or finer, and will have mFlick sensitivity with a cooled camera, andSBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
SBC: CFD RESEARCH CORPORATION Topic: CBD12102
Protein manufacturing is of paramount importance to chemical and biological defense applications. High-throughput protein purification is a critical need for rapidly scaling the target protein product. Existing purification methods primarly rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermea ...SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
A Novel, Aerodynamics-augmented Continuous Ionization System for Electrostatic Collection of BioaerosolsSBC: CFD RESEARCH CORPORATION Topic: CBD12107
Safe and efficient air ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these issues, we propose to develop and demonstrate a novel bioaerosol ionization and collection ...SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
SBC: PIASECKI AIRCRAFT CORP Topic: CBD12108
Piasecki Aircraft proposes to meet the challenge of delivering a biological or chemical sample maintained at less than -20 deg Celcius over a range of up to 1000 miles with a precision landing with a portable unmanned aerial system capable of a vertical takeoff, cruise flight range typical of a fixed wing platform, and able to perform a precision landing. The system consists of a lifting quadrotor ...SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
SBC: Nico Technologies Corp. Topic: CBD10103
The drug R&D cycle is long and very expensive. In many ways, this status quo can no longer be sustained. One of the reasons for such great cost is that the vast majority of drug candidates are screened out at the stages of animal and human trials. More efficient methods of testing of drugs at the stage of ex-vivo studies, which are substantially less expensive than animal and human testing cyc ...SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
SBC: MARINE1 LLC Topic: SOCOM10005
Marine 1, LLC and senior business partner Moxahela Enterprises, LLC are pleased to present this proposal for the US Special Operations Command (USSOCOM) Small Business Innovative Research (SBIR) topic number SOCOM10-005 for high speed combatant craft automated ride control. USSOCOM has identified the need for a lightweight, automated ride control system that will model and predict craft motion to ...SBIR Phase I 2010 Department of DefenseSpecial Operations Command