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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. STTR Phase I: Sustained Delivery of Peptides with Inverse Flash Nanoprecipitation

    SBC: Optimeos Life Sciences, Inc.            Topic: BM

    This STTR Phase I project aims to pioneer a novel approach for the sustained delivery of peptide therapeutics using nano-composite microparticles. Peptide therapeutics tend to suffer from rapid enzymatic degradation and clearance, with half-lives on the order of minutes, and require frequent injections. The goal of a sustained release formulation is to reduce the frequency of injections by slowly ...

    STTR Phase I 2019 National Science Foundation
  2. STTR Phase I: A Machine Learning Toolbox to Identify Therapeutics for Rare Genetic Disorders from Phenotypic Screens on Micropattern-Based Organoids

    SBC: RUMI SCIENTIFIC, INC.            Topic: BT

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to develop a widely applicable, innovative pipeline for drug discovery against rare genetic disorders. While each orphan disease affects a small fraction of individuals, thousands exist, affecting 400 million people world-wide. The challenge to bring therapies to the clinics for diseases th ...

    STTR Phase I 2019 National Science Foundation
  3. STTR Phase I: Development of a Transparent, Near-Ultraviolet Photovoltaic Power Source for Wireless Operation of Smart Windows and IoT Devices

    SBC: Andluca Technologies Inc.            Topic: PH

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is a transparent photovoltaic technology that converts near-ultraviolet (NUV) light into point-of-use power for dynamic 'smart' windows. Energy use in buildings represents roughly 40% of total U.S. energy demand. It is projected that over half the buildings that will be in use in 2050 are alre ...

    STTR Phase I 2019 National Science Foundation
  4. STTR Phase II: Microgames for Improving Pediatric Compliance

    SBC: ARCHIE MD INC.            Topic: DG

    The innovation proposed in this Small Business Innovation Research Phase II project will harness the popularity and ubiquity of mobile microgames on hand-held devices for educating children on self-management of chronic health conditions. Millions of children suffer from chronic conditions which require regular management, such as diabetes, or from broader states of poor health caused by obesity. ...

    STTR Phase II 2013 National Science Foundation
  5. STTR Phase I: A novel combinatorial technology for engineering product tolerance traits in yeast

    SBC: PRIMORDIAL GENETICS, INC.            Topic: EB

    This Small Business Technology Transfer (STTR) Phase I project proposes to engineer butanol tolerance in the yeast Saccharomyces cerevisiae using a novel combinatorial genetic technology designed to enable yield enhancements in microbial production organisms. Microbial production of renewable fuels and chemicals is rapidly expanding. However, toxic products or by-products and engrained metabolic f ...

    STTR Phase I 2013 National Science Foundation
  6. Epitaxial GaN on flexible metal tapes for low-cost transistor devices

    SBC: IBEAM MATERIALS, INC.            Topic: 1

    GaN-based devices are the basis of a variety of modern electronics applications, especially in optoelectronics and high-frequency / high-power electronics. These devices are based on epitaxial films grown on single-crystal wafers. The single-crystal wafer substrates are limiting because of their size, expense, mechanical properties and availability. If one could make GaN-based devices over large a ...

    STTR Phase I 2013 Department of EnergyARPA-E
  7. STTR Phase I: Quantum Cascade Laser Spectrometer for Bio-medical Applications

    SBC: Princeton Technology Advisers Company Inc.            Topic: EB

    This Small Business Technology Transfer (STTR) Phase I project will involve research and development of mid-infrared multi-spectral imaging, leading to the first commercial instrument capable of chemical imaging of bio-medical samples. We will develop and demonstrate key technologies to dramatically improve the sensitivity and image contrast of live tissue and other biological samples in-situ. Con ...

    STTR Phase I 2013 National Science Foundation
  8. STTR Phase I: High-Yield Hydrogen Production from Biomass Sugars by Cell-Free Biosystems for Mobile Electricity Generation

    SBC: Cell-Free Bioinnovations Inc.            Topic: EB

    This Small Business Innovation Research Phase I project will scale up high-yield hydrogen production from maltodextrin and water mediated by cell-free enzymatic biosystems and develop prototype mobile electricity generators (MEGs). Cell-free biosystems for biomanufacturing (CFB2) implement complicated biochemical reactions in one pot by the in vitro assembly of more than three enzymes and/or cofac ...

    STTR Phase I 2013 National Science Foundation
  9. STTR Phase I: Microbial Production of Catechins

    SBC: ChromaDex Inc.            Topic: EB

    This Small Business Technology Transfer (STTR) Phase I project proposes to establish cost effective methodologies for the efficient production of catechins utilizing a microbial fermentation approach. Preliminary work on the biosynthesis of the catechins, using metabolically engineered Escherichia coli recombinant strains from their flavanone and phenylpropanoid acid precursors, has demonstrated f ...

    STTR Phase I 2013 National Science Foundation
  10. STTR Phase I: Performance Optimization Toolbox for Wave Energy Conversion Devices

    SBC: Re Vision Consulting LLC            Topic: AS

    This Small Business Technology Transfer Phase I project is titled ?Performance Optimization Toolbox for Wave Energy Conversion Devices?. Advanced wave prediction and concurrent online adjustment of the operating parameters (such as hydraulic system pressure and generator load) of existing wave energy conversion (WEC) devices have the potential to increase their power extraction efficiency by at le ...

    STTR Phase I 2013 National Science Foundation
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