Award Data

This Small Business Technology Transfer (STTR) Phase I project aims to apply computational protein design (CPD) to engineer polysaccharide monooxygenases (PMOs) for improved thermostability, so that a cocktail of PMOs and key cellulases will more efficiently convert lignocellulolosic biomass to fermentable sugars. The objectives of Phase I are to: (a) evaluate several natural PMOs for expression, ...

The broader impact of this Small Business Technology Transfer (STTR) Phase I project is to enable a much wider adoption of various photomedical treatments. Broadly speaking, photomedical treatments use light to cure diseases and promote healing. Specifically, photodynamic therapy uses light to activate a photosensitizing chemical agent to kill cancer cells or bacterial with minimal side effects. M ...

This Small Business Innovation Research Phase I project will scale up high-yield hydrogen production from maltodextrin and water mediated by cell-free enzymatic biosystems and develop prototype mobile electricity generators (MEGs). Cell-free biosystems for biomanufacturing (CFB2) implement complicated biochemical reactions in one pot by the in vitro assembly of more than three enzymes and/or cofac ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase II project is the development of software to help bioscientists analyze more tissue in less time and with higher accuracy and reproducibility. Currently, stereology studies require a trained technician to sit before a computer screen, making tedious manual counts (clicks) on hundreds to thousands of mic ...

This Small Business Technology Transfer (STTR) Phase II project proposes the development of an integrated powered knee-ankle prosthesis. The objective of this proposal is to investigate the use of integrated powered knee and ankle joints in trans-femoral prostheses that use sensory information from the ground and the wearer. The hypothesis is that a prosthesis with actively powered knee and ankle ...

This Small Business Technology Transfer (STTR) Phase II project proposes will study the technology barriers associated with creating exoskeleton assist devices for workers in distribution centers and automobile assembly plants. By using these devices, workers can dramatically reduce the load in the vertebrae of the lower back when maneuvering parts and boxes. The assist device will take the majori ...

This Small Business Technology Transfer (STTR) Phase II project will transform the Hybrid Optimization Model for Electric Renewables (HOMER

The innovation proposed in this Small Business Innovation Research Phase II project will harness the popularity and ubiquity of mobile microgames on hand-held devices for educating children on self-management of chronic health conditions. Millions of children suffer from chronic conditions which require regular management, such as diabetes, or from broader states of poor health caused by obesity. ...

The broader impact of this Small Business Technology Transfer (STTR) Phase I project includes the development of new tools and methods for detecting and managing insect populations in the agricultural sector. The benefits of improved information about insect populations are substantial, including increased farm revenues through avoided pest damage and improved pollinator activity, and increased ac ...

This Small Business Technology Transfer (STTR) Phase I project aims to develop roll-to-roll processing of highly efficient, thin film photovoltaics on inexpensive polycrystalline substrates. The innovation lies in an architecture that yields near-single-crystalline thin films even on polycrystalline substrates. This innovation will be combined with the benefits of hot wire chemical vapor deposit ...