Award Data

DESCRIPTION (provided by applicant): Becoming a mother is a significant transition in a woman's life. This transition can precipitate major changes in health behaviors, like physical activity. Once a woman has a child she is much less likely to participate in regular, moderate to vigorous physical activity compared to women without children. Thus, new mothers are at risk for future weight gain and ...

The Bumps: A Device for Rapid, Non-Invasive Quantification of Touch Sensation Abstract !Our proposal describes an elegant device called the Bumps that quantifies finger pad touch sensation at low micron levels. The objectives are to diagnose peripheral neuropathy near its onset, when the possibility for reversal is highest, and to monitor either progression or reversal of neuropathy during treatme ...

Type 1 Diabetes (T1D) affects an ever growing population. While this disease typically has been associated with juveniles, the disease in adult populations is rapidly increasing. The defining clinical component is insulin loss, which occurs because of sustained inflammation in the islets. At present there is no means to prevent or reverse insulin loss. A major inflammatory pathway in T1D that cont ...

Developing knowledge-driven nanoelectronics for military applications requires understanding the fundamental physics that governs the behavior of the underlying material. Strongly correlated materials have very desirable properties such as interfacial superconductivity, ferroelectricity, ferromagnetism, and huge magnetoresistance, which make them an ideal set of candidates to integrate with semico ...

Optically pumped magnetometers provide very high performance but they cost tens of thousands of dollars, and they are large and power hungry. Recently we successfully developed and commercialized laser pumped magnetometers with size, weight and power consumption that is an order of magnitude below current state-of-the-art without sacrificing performance. In this project, the focus will be on produ ...

ATR proposes the development of an innovative Advanced Dual-Purpose Elevator System (ADPES) that can be installed on an Expeditionary Base Mobile (ESB) so that aircraft and cargo can be transferred from the flight deck to the mission bay and watercraft like the Combatant Craft Medium (CCM) can be launched and recovered from mission bay to the sea. The ADPES consists of a submersible platform and t ...

Abstract. LEXEO Therapeutics, LLC, is an early stage biotechnology company focused on using gene therapy technologies to protect vulnerable organs from oxidant stress. LEX01, the 1st LEXEO product, is a 1st in class, next generation gene therapy treatment for alpha 1-antitrypsin (AAT) deficiency, an autosomal recessive hereditary disorder associated with low serum levels of AAT. AAT (SERPINA1), a ...

The overarching objective of this research and development effort is to advance the current state of human-robot interaction (HRI), developing a theoretically and empirically-based design science that is grounded in best practices and validated principles of human performance and human-systems integration (HSI). The resulting scientific methodology and design process will support improved methods ...

HYPRES, in collaboration with University of Massachusetts, proposes an energy-efficient hybrid-temperature-heterogeneous-technology (HTHT) digital data link for interfacing 4K superconductor electronics with room-temperature electronics. Comprising several stages of cryogenic SiGe amplifiers at different temperatures, followed by equalization techniques, this data link will be designed to minimize ...

The Navy's role in the Global War on Terrorism (GWOT) has necessitated a variety of activities that require long-term, reliable intelligence, reconnaissance, and surveillance. For tactically relevant applications, the endurance and performance tradeoff remain the limiting factors in determining how long sensing and analytic capabilities can remain operative while unattended. In this proposal, Inte ...