Award Data

NextGen Aeronautics (NextGen) and University of Southern California (USC, RI) team of experienced composite materials, structural design, and analyses personnel are responding to the opportunity to develop stochastically verified composite structural desi

HJ Science & Technology (HJS & T) and the Joint BioEnergy Institute (JBEI) propose to develop an automated, software-controlled, programmable, low-cost, and compact platform capable of running rapid and complex bioengineering processes and optimization of new biomanufacturing systems. Our approach combines the microfluidic automation technology of HJS & T with the novel synthetic biology technolo ...

Genome-scale predictable cellular design and engineering of biomanufacturing systems is the overarching a goal of DARPA's Living Foundry thrust and, if realized, will enable rapid engineering of living biosystems for a broad range of applications in biotechnology and pharmacology. However, constructing living cells with designed genome is not fully automated and is severely limited by inhere ...

As the importance of social networks skyrockets, so does the need to understand human behavior in these forums. While statistical analyses can help to some extent, many types of patterns are simply not visible by looking at raw numbers. However, many of these patterns do emerge in visualizations, and the innate human ability to see these patterns in graphical depictions represents a valuable oppo ...

Opportunity: Guayule, a US native plant, is the only alternate rubber crop with an established, mechanized, agronomic system. Problem: Low rubber yields and lack of effective resin and bagasse coproduct valorization, have prevented widespread adoption by American farmers and processors. Rubber is only made when the cytoplasmic monomer pool (isopentenyl-pyrophosphate; IPP) is larger than that requi ...

Stottler Henke proposes PaCT, leveraging our related past work in computer vision and machine learning. Drawing from techniques used in ExPATSS, a Phase II SBIR effort slated for transition to the Naval fleet, PaCT will perform bacterial characterization using features derived from the phenotype of the bacteria. PaCT will predict bacterial characteristics such as pathogenicity, antibiotic resistan ...

The use of continuous glucose monitors can be an invaluable management tool for patients afflicted by glycemic variability due to critical illness or trauma. Maintaining stable glucose levels enhances health and lowers care costs, and individuals equipped with continuous glucose data have significantly improved outcomes. Profusa has developed highly miniaturized, injectable, tissue-like, glucose s ...

As unmanned aircraft systems (UAS) become more prevalent there is an increasing desire to automate UAS navigation and control. To enable future UASs to perform a wider variety of missions, the they must be able to complete autonomous relative navigation to accomplish missions. Current technologies rely heavily on GPS measurements, which are undesirable since GPS signals may be unavailable in many ...

Nanoscale, material sensitive, imaging techniques are critical for progress in many disciplines as we learn to master science and technology at the smallest dimensions — on the nanometer to atomic-scale. However, progress in both science and technology is becoming increasingly limited by the constraints of current imaging techniques and metrologies. Fortunately, by combining coherent extreme UV ...

This Phase II project aims to assemble the key set of sensor modalities that are needed to reliably view the key process anomalies and properties of laser powder bed fusion. The research team will down-select from the Phase I sensors investigated and integrate the sensors into a sensor fusion software package that facilitates data collection and synchronization, and eventually feedback control of ...