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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Blood Brain Barrier (BBB) Permeable Encapsulating Agents for Effective Delivery of CNS-active Agents
SBC: LYNNTECH INC. Topic: CBD08107Drug transport in the central nervous system is highly regulated by the Blood-Brain Barrier (BBB). Most medicines, including many for treating cancer, Alzheimer’s, and stroke, do not meet essential criteria, such as lipophilicity and low molecular weight, required for appreciable transport into the brain. However, endogenous peptides, such as insulin or transferrin, and certain monoclonal anti ...
SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense -
Reagentless and Realtime Detection of Airborne Microorganisms
SBC: LYNNTECH INC. Topic: CBD06102Biological weapons are among the most serious threats facing the United States defense forces, today. Currently available bioaerosol sampling systems and cassettes require both sample preparation and a well equipped laboratory for analysis. Other detection methods rely on fragile bio-molecules for recognition of the target analyte. These systems are not suitable for onsite analysis. Infrared spec ...
SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense -
Self-Detoxifying, Disposable Protective Garments
SBC: LYNNTECH INC. Topic: CBD06108While zero-based tolerance protective clothing is suitable for first responders, it provides an unnecessary level of protection for first receivers who are exposed to a considerably reduced threat. The use of zero-based tolerance garments by first receivers is particularly problematic since they often work in the same garments for an extended period of time. Consequently, the unique needs of fir ...
SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense -
Sequential Isoelectric Point Separation of Proteins Using Non-Gel, Microfluidic System
SBC: LYNNTECH INC. Topic: CBD08101The measurement of biochemical changes within the human body can provide a means to monitor a person’s physiological health. Many of the biochemicals that provide a snapshot of a person’s health are proteins. The challenge with measuring proteins is the existence of approximately ten orders of magnitude difference in concentration between the most abundant proteins in blood and those typically ...
SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense -
MOEMS Miniaturized Real-time Visible/UV Spectrometer
SBC: MORGAN RESEARCH CORP. Topic: N/A"This Phase I SBIR proposal is for the initial development of a miniaturized real-time visible/UV spectrometer based on micro-opto-electro-mechanical systems (MOEMS) technology. Use of MOEMS technology enables orders of magnitude reductions in size, weightand power from the smallest spectrometers commercially available today and virtually assures exceeding stated corresponding SBIR requirements. ...
SBIR Phase I 2002 Department of DefenseOffice for Chemical and Biological Defense -
Imidazenil: A Protective Agent Against Chemical Warfare Agents induced Status Epilepticus
SBC: NEUPHARMA, INC. Topic: CBD05116The overall objective of this Phase II proposal is to determine the advantages of imidazenil over diazepam or midazolam as a potential anticonvulsant agent for the prophylaxis and for the emergency treatment of organophosphate nerve agent exposure. Therefore, we will compare the dose-dependent efficacy and anticonvulsant tolerance liability of imidazenil or midazolam for protecting rats against di ...
SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense -
Development of Array-Based Universal Biosensing Devices Based Upon Intelligent Oligonucleotide Probe Sets
SBC: Vitruvius Biosciences Topic: N/A"The present proposal describes strategies leading to the development of an array-based universal biosensor for detecting and differentiating microbial species, or differentiating at the DNA or RNA level between cell types of the same species. The proposed strategy relies on the differential hybridization of genomic DNA, extrachromosomal DNA, mRNA, or ribosomal RNA from different sources to a comm ...
SBIR Phase I 2002 Department of DefenseOffice for Chemical and Biological Defense -
Enhanced Capability Point Combined Bio and Chem Sensor
SBC: VOXTEL, INC. Topic: CBD07105Many chemical agents have unique absorption spectra in the 9-to-11μm wavelength range, and sufficient absorption cross sections for detection at trace concentration levels. In this proposal, a short standoff range LWIR DISC LIDAR will be developed, providing comprehensive chemical and biological standoff detection, as well as MWIR detection of industrial chemicals. The LIDAR is based on a 1 mm di ...
SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense -
Enhanced Capability Point Combined Bio and Chem Sensor
SBC: VOXTEL, INC. Topic: CBD07105In this Phase II program, to enable long-standoff-range, small-sized, high-performance, cost-effective LWIR DISC LIDAR systems, a six-element array of 1-mm, segmented HgCdTe avalanche photodiodes (APDs) will be designed, optimized and each APD will be directly coupled to a unique narrow-band cold-filter, with unique spectral bandpass filters
SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense -
Aptamer-Enhanced Biorecognition Reagent System
SBC: OMNISITE BIODIAGNOSTICS, INC. Topic: N/A"OmniSite BioDiagnostics, Inc. (OmniSite) proposes to develop DNA Aptamers to Bacillus anthracis (nonpathogenic Sterne strain) spores and staphylococcal enterotoxin B (SEB) by the SELEX process. Aptamers are less expensive than antibodies to produce, do notrequire animal hosts for production, can be protected from nucleases, and used in a variety of assay formats to replace antibodies. In Phase I, ...
SBIR Phase I 2002 Department of DefenseOffice for Chemical and Biological Defense