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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Advanced Simulated Patient Intelligent Response Engine (ASPIRE)
SBC: VCOM3D INC Topic: DHA191002The goal of medical simulation-based training such as high-fidelity manikin simulators, part task trainers, and screen-based virtual patients, is to approximate real-life treatment experiences without risk to live patients. While the use of sensors has ma
SBIR Phase I 2019 Department of DefenseDefense Health Agency -
Advance Early Detection of Lupus Nephritis with ClearGold
SBC: CLEARNANO INC Topic: 400SummarySystemic lupus erythematosusSLEor lupus is an autoimmune disease that impacts more thanmillion people worldwideincludingmillion AmericansNearlyof these patients will develop lupus nephritiswhich can cause kidney failureAs a resultits financial burden to individual patient can reach $yearmuch higher than many other diseases because of kidney transplantationAlthough early treatment of lupus n ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
A facile synthesis of optically pure disubstituted amino acids
SBC: MONOMERCHEM, inc Topic: 300Project Summary Enantiopuredisubstituted amino acidsEDAAsare valuable fundamental building blocks for medical research in both academics and industryWhen an EDAA is incorporated into the framework of a peptide or a small moleculeboth substituents attached to thecarbon contribute to the moleculeandapos s shapebiological activity and physical propertiesEDAAs can be used to optimize stabilityclogPand ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
A fast, scalable, cost-effective, single-stranded library protocol for cell-free DNA
SBC: Claret Bioscience LLC Topic: 102Project Summary Liquid biopsy is a potentially powerfulnon invasive approach for detectingclassifying and monitoring tumors by capturing cell free DNA molecules found circulating in blood and other bodily fluidsAny next generation sequencingNGSbased approach requires an efficient protocol for converting cell free DNA into a sequencing libraryNearly all currently available NGS library preparation m ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
A gel patch for replacing surgical eardrum repair with an office-based procedure
SBC: TYMPANOGEN, INC. Topic: NIDCDABSTRACT Chronic perforations of the tympanic membraneTMaffect overpatients in the United States annuallyoften stemming from ventilation tubes inserted in the TM to drain fluid from middle ear infectionsLeft untreatedthese TM perforations can lead to significant morbidities that include recurrent ear infectionconductive and sensorineural hearing lossmastoid bone infectionand cholesteatoma developm ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
A high-efficiency, low-cost, single-use purification technology for therapeutic antibody manufacturing
SBC: Bondwell Technologies Inc. Topic: 400Therapeutic antibodies have had a profound impact on treatment of many types of cancer and autoimmune diseasesAs a resultfive of the top ten best selling drugs ofwere therapeutic antibodiesMore than seventy therapeutic antibodies have been approvedand over six hundred antibody based products are in clinical developmentHoweverantibodies are extremely expensive to produceand large amounts of antibod ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
AHTP-comet: development of an automated, high throughput comet assay system
SBC: ENGINEERING RESOURCES GROUP INC Topic: NIEHSPROJECT SUMMARY Genomic instabilityinduced by DNA damageand partly mitigated by DNA repair and antioxidantsplays a critical role in the pathogenesis of many major human diseasessuch as neurodegenerationcancer and cardiovascular diseasetogether with agingThere is a critical need for automated assays that can perform these assessmentsand bring them into greater routine usewhich will help advance our ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
A Large-Scale Microfluidics Imaging Platform for High-Throughput Toxicity Testing using Canine Intestinal Organoids
SBC: VIVOVERSE, LLC Topic: NIEHSProject SummaryCurrentlytoxicology studies require a large number of animal testing to identify better and safer drug candidatesIn an attempt to reduce the use of large animals in pharmaceutical industrythere is a need to bridge the gap between the conventional in vitro cell based assay and the non human animal studiesRecentlythreedimensional models are gaining momentum and replacing conventionalD ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Algorithm to Identify Patients at Risk of Medication-Related Hospitalization
SBC: L. KRENK, INC. Topic: RThe long range goal of this fast track research application is to improve healthcare quality and reduce healthcare costs nationwide among those at risk for medication related hospitalizationThe specific objective of this proposed research is to develop an algorithm that uses existing electronic health information to efficiently identify patients at risk of medication related hospitalization so tha ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
ALow Blood Volume Platform for Global Newborn Screening of Common, Treatable Conditions
SBC: BAEBIES, INC. Topic: NICHDAn estimated 80% of babies born worldwide (approximately 100 million each year) currently do not receive any newborn screening care. Newborn screening (NBS) is an immensely successful testing program that identifies those at increased risk for common, treatable congenital disorders; the pre-symptomatic identification of these disorders in newborns enables the rapid initiation of treatments and red ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health