For best search results, use the search terms first and then apply the filters

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Iprompt to Improve Teaching of Students with ASD

    SBC: Handhold Adaptive, LLC            Topic: N/A

    This project will develop the iPrompt software, for use with iphones and ipdads. Teachers will employ the tool with flexible and unobtrusive strategies to support students with Autism Spectrum Disorder (ASD). The main features of the iprompt are the Video Modeling Library and the Community Media Library, a teacher’s professional development manual, and video Modules to support teacher use of ...

    SBIR Phase I 2010 Department of Education
  2. Volunteer, Employment, and Internship Web Solutions


    The Volunteer, Employment, and Internship Web Solutions project will produce a web-based services that provide students with employment, volunteer, and internship opportunities to prevent students from dropping out of school. The website will connect students to local businesses and civic organizations. The intervention will include teacher professional development and support. Phase I work will d ...

    SBIR Phase I 2010 Department of Education
  3. Readorium Software for Improved Reading Comprehension

    SBC: Mtelegence Corporation            Topic: N/A

    Readorium will develop a desktop software to support students struggling with reading comprehension in middle school science. The software teaches readers the special features of nonfiction text and strategies for reading comprehension. The games will include an avatar to guide the student, multi-media articles of differing levels of difficulty that are aligned to standards, and embedded assessmen ...

    SBIR Phase I 2010 Department of Education
  4. Novel Antibacterial Agents That Target DNA Replication in Mycobacterium tuberculo

    SBC: Achillion Pharmaceuticals, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Mycobacterium tuberculosis (MTB) is probably the most ubiquitous microbial pathogen in the world today infecting one-third of the total population and causing millions of active tuberculosis (TB) cases each year. The economic costs are substantial and more than one million people die of TB infections each year. Before the arrival of antimicrobial therapy, TB wa ...

    SBIR Phase I 2010 Department of Health and Human Services
  5. Accelerated Discovery and Development of New Pain Therapeutics


    DESCRIPTION (provided by applicant): Neuropathic pain is a common complication of cancer, diabetes mellitus, viral infections, and other causes. Although physicians currently employ a variety of treatments to manage moderate to severe neuropathic pain, including non-steroidal anti-inflammatory drugs, opioids, tricyclic antidepressants, anti- seizure medications, serotonin-norepinephrine reupta ...

    SBIR Phase II 2010 Department of Health and Human Services
  6. Development of a method to multiplex ChIP-SEQ and ChIP-chip experiments

    SBC: AFFOMIX, INC.            Topic: NHGRI

    DESCRIPTION (provided by applicant): The immediate objective of our research is to generate a method that will enable researchers to multiplex Chromatin ImmunoPreciptation-Sequencing (ChIP-Seq) analysis in a single Next generation DNA sequencing run. In the to-be-developed method: i) a set of antibodies directed against specific DNA-binding proteins are uniquely bar-coded with a DNA 'ZipCode;' ii) ...

    SBIR Phase I 2010 Department of Health and Human Services
  7. High-throughput screening and identification of scFv antibodies against glycosyla

    SBC: AFFOMIX, INC.            Topic: NCRR

    DESCRIPTION (provided by applicant): The specific goal of this proposal is to develop a high-throughput method to identify scFv antibodies that recognize post-translationally modified proteins. We propose to complete a proof-of-concept for a new type of affinity screening process based on emulsion, secretion, and capture, which we term ESCape . In the proposed phage ESCape method, E. coli transfo ...

    SBIR Phase I 2010 Department of Health and Human Services
  8. A bifunctional antibody screening system for both phage display and yeast two-hyb

    SBC: AFFOMIX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): This is a proposal to establish a proof-of-principle for a vector system to isolate high-affinty antibodies through selective rounds in both yeast and Escherichia coli. Antibodies have quickly become extremely useful as therapeutic medicines to treat a wide-variety of disorders. We propose to develop a means of making the discovery of immunotherapeutics faster ...

    SBIR Phase I 2010 Department of Health and Human Services
  9. A Flow Through Cell Counting Assay

    SBC: Allied Innovative Systems LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): The long-term goal of the proposed research is to develop a novel quantitative flow through cell counting method for enumeration of CD4+ T lymphocytes in human blood. CD4 cell counts are needed to stage and monitor HIV-infected patients. In adults, the absolute number of CD4+ T cells per microlitre of blood has critical prognostic and therapeutic implications, ...

    SBIR Phase I 2010 Department of Health and Human Services
  10. High throughput screening of bacterial collections for surface proteins of commer

    SBC: APD LIFE SCIENCES, INC.            Topic: NCRR

    DESCRIPTION (provided by applicant): There is a recognized need for development of protein capture tools that will reliably detect a variety of targets, over a broad range of concentrations, for use with human plasma and other complex sample mixtures for diagnostic and therapeutic applications. The products from our PEARL [Pathogen-Encoded Adaptable Receptor Library] technology will yield antibody ...

    SBIR Phase I 2010 Department of Health and Human Services

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government