Award Data

Advanced Technologies Group, Inc. proposes the development of a Liquid-Oxygen Mass Gauge, (LMG) for In-Space cryogenic storage capable of continuous monitoring of liquid quantities to better than 1% accuracy. The proposed sensor builds on previous liquid hydrogen sensor development successes and patents. It can be utilized to measure cryogenic propellants, and sub-critical cryogenic fluids in us ...

Advanced Technologies Group, Inc. proposes the development of a Cryogenic Flow Sensor (CFS) for determining mass flow of cryogens in spacecraft propellant management. Current point sensor technology is incapable of determining high pressure, high flow rate cryogenic fluid quality and mass flow rate, and has proven to be inaccurate in attempting to rapidly measure cryogen depletion. If there is a ...

Communications security (COMSEC) role in space continues to grow as the available bandwidth expands. The DOD Transformation Communications (TC) vision will transform the space, air and ground networks into a fully integrated internet like network. This vision requires cryptographic architectures that satisfy Crypto Modernization requirements, can host current and future cryptographic algorithms, ...

The optimal design for a rapidly-deployable, airborne HAB identification sensor requires the determination of the minimum spectral, spatial, dynamic range, and deployment capabilities necessary to achieve the goal of operational detection. This sensor must be capable of rendering a positive identification, with a low false alarm rate, in optical shallow waters, where the bottom is visible in the ...

DESCRIPTION (provided by applicant): In this proposal, we present a novel approach for the identification and immobilization of a BMP mimetic. We plan to use phage display technology to identify peptides that mimic BMP-like signaling of the BMP receptors. These peptides will be linked to a previously identified high-affinity, collagen-binding peptide. The resulting hybrid molecule will allow contr ...

Endosseous metallic implants are common alloplastic devices used in medicine and dentistry. The orthopedic and dental marketplace continues to grow and indications for implants are expanding. There is a perceived need to improve both the successful healing (osseointegration) and the long term outcome of implants by control of interfacial reactivity during healing and remodeling. The growth of know ...

DESCRIPTION (provided by applicant): In this Phase I SBIR project Alderon Biosciences Inc. (ABI) proposes to demonstrate the feasibility of using electrochemical reverse transcriptase (eRT) assays for determinations of HIV viral load in clinical samples. Success will set the stage for Phase II development, FDA approval, and production of commercial kits using this advanced technology. The long-r ...

DESCRIPTION (provided by applicant): The National Institutes of Allergy and Infectious Disease have called for better tools for the detection and diagnosis of emerging and re-emerging infectious diseases. To meet this need, Alderon Biosciences Inc. (ABI) proposes to develop innovative, low-cost tests with sensitivity adequate for determining HCV viral load. Reliable and affordable HCV viral load t ...

DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

DESCRIPTION (provided by applicant): The objective of this project is to develop an anti-tissue factor antibody, Sunol-cH36, as a treatment for Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS). The association between coagulation and inflammation has been well established and a central role in the coagulopathy of ALI/ARDS has been attributed to tissue factor (TF). TF binding ...