Award Data

THIRTY FOUR MILLION AMERICANS ARE AT LEAST 20 PERCENT OVER THEIR IDEAL WEIGHT. THE EXCESS WEIGHT HAS SERIOUS HEALTH IMPLICATIONS BECAUSE OBESITY HAS BEEN ASSOCIATED WITH PREMATURE MORTALITY. AT ANY POINT IN TIME, AS MANY AS 35 PERCENT OF ADULT AMERICANS ARE ATTEMPTING TO LOWER THEIR WEIGHT AT AN ANNUAL COST OF $5 BILLION. HEALTH INNOVATIONS, INC. WILL DEVELOP A WEIGHT MANAGEMENT PROGRAM THAT RELIE ...

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THIS PROJECT WILL EXAMINE THE NEEDS OF OLDER PERSONS FOR IMPROVEMENTS IN THE INTERFACE DESIGNS OF HAND-HELD CONTROL UNITS FOR REMOTELY CONTROLLING EQUIPMENT AND SOFTWARE, ESPECIALLY TELEROBOTS. THESE REMOTE CONTROL UNITS (RCUS), PROLIFERATING WITHOUT ADEQUATE HUMAN FACTORS ENGINEERING, WILL BE USED INCREASINGLY BY SENIORS IN THEIR HOMES AND AT WORK. THE ONLY STUDY OF RCUS INDICATES THAT THEIR OPER ...

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MOTOR OPERATED GATE VALVE OPERABILITY PROBLEMS AND FAILURES AT NUCLEAR POWER PLANTS ARE A MAJOR SAFETY CONCERN AS STATEDIN NRC IE BULLETIN 85-03 AND GENERIC LETTER 89-10. THIS PROPOSAL IS AIMED AT IMPROVING GATE VALVE PERFORMANCE BY (1) DEVELOPING COMPREHENSIVE PERFORMANCE PREDICTION MODELS FOR USE OVER A RANGE OF OPERATING CONDITIONS, (2) DEFINING LIMITS, BASED ON SPECIFIC DESIGNS, BEYOND WHICH E ...

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IT IS PLANNED TO DEVELOP A MINIATURIZED SURFACE ACOUSTIC WAVE (SAW) VAPOR DETECTION SYSTEM AS A PERSONAL MONITOR FOR TOXIC ORGANIC VAPORS. THE SAW SENSORS ARE VERY PROMISING ASTHEY CAN BE MADE VERY SENSITIVE TO ESSENTIALLY ANY TOXIC ORGANIC COMPOUND WITH AT LEAST MODEST VAPOR PRESSURE. THEY CAN DETECT SOLVENTS SUCH AS BENZENE AND DICHLOROETHANE IN THE LOW PPM RANGE AND MANY OF THE HIGH MOLECULAR, ...

MOLECULAR ANALYSIS, INC. (MAI) HAS DEVELOPED AN IN SITU HYBRIDIZATION PROCEDURE THAT IS RAPID (LESS THAN 2 HOURS), SENSITIVE (CAN DETECT ONE MOLECULE), INEXPENSIVE (REAGENTS COST LESS THAN $1.00), AND NONISOTOPIC. THIS PROCEDURE IS READY FOR TESTING THE FEASIBILITY OF USING IT TO DETECT THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) IN THE PERIPHERAL BLOOD OF INDIVIDUALS WITH EVIDENCE OF INFECTIO ...

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THE SPECIFIC AIM IS TO DEVELOP HUMAN CELL LINES CONTAINING SPECIFIC, CLONED GENES OF THE PATHOGENIC VIRUS, HIV, THE CAUSATIVE AGENT OF AIDS. EACH CELL LINE WILL CONTAIN ONLY ONE INDIVIDUAL GENE OF HIV, EXPRESSED BY A EUKARYOTIC GENE PROMOTER. THESE CELL LINES WILL PROVIDE A NONINFECTIOUS, POSITIVE CONTROL STANDARD FOR SUCH DIAGNOSTIC MOLECULAR TESTS AS SOUTHERN ANALYSIS, NORTHERN ANALYSIS, IN SITU ...