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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Novel physiological depot formulations for long-term butyrylcholinesterase delivery

    SBC: AVRYGEN CORPORATION            Topic: CBD13107

    Oraganophosphorus poisons are potent nerve agents that function by inhibiting the action of acetylcholinestrase in nerve cells. Of these, G-class nerve agents including: Taubin, Soman and Saurin, and, V class agents such as VX represent a significant threat to US military personnel. Human plasma enzyme, Butyrylcholinesterase detoxifies organophosphates by making a covalent bond with them at stoich ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  2. Novel MicroPower Source for Insect Based Sensor and Communication Platforms

    SBC: CFD RESEARCH CORPORATION            Topic: CBD09105

    Our objective is to develop a novel micropower source, microsensor, and communication chip for integration with an insect, thereby delivering a state-of-the-art unmanned chemical detection device. The proposed biological fuel cell (Bio-FC) will leverage ongoing research at CFDRC and provide a compact/lightweight power supply, for mounting on numerous types of insects and producing necessary power ...

    SBIR Phase I 2009 Department of DefenseOffice for Chemical and Biological Defense
  3. Novel Conjugation Sites for Antigen Binding Reagents

    SBC: SOLULINK BIOSCIENCES            Topic: N/A

    "This project proposes to cost effectively prepare scFv or Fab antibody fragments that have been modified to site-specifically incorporate stable linkable moieties that will allow their conjugation to reporter molecules and surfaces without comprising thebiological function of the binding site of the antibody fragment. The ready availability of technologies to prepare these antibody fragments wit ...

    SBIR Phase I 2002 Department of DefenseOffice for Chemical and Biological Defense
  4. Novel Circulating RNA-based Markers as Diagnostic Biomarkers of Infectious Diseases

    SBC: CFD RESEARCH CORPORATION            Topic: CBD18A001

    In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  5. Novel Approaches to Fully Digital Optical Solutions

    SBC: TOYON RESEARCH CORPORATION            Topic: SOCOM15003

    Digital optical solutions currently have inherent latency due to the processing chain from optical capture with a lens to a display. While system latency in excess of 5 milliseconds is acceptable in most applications where an operator is seated, this threshold is too high for the TALOS application. Being able to move dynamically while processing a digital image of the environment will require a ...

    SBIR Phase I 2015 Department of DefenseSpecial Operations Command
  6. Non-Invasive Monitoring of Changes in Intracranial Pressure Due to Infections in the Central Nervous System

    SBC: Fenix Research Corporation            Topic: CBD192005

    Infections of the central nervous system (CNS) are associated with brain swelling and increased cerebral blood volume, as well as focal cerebral perfusion deficits, variable levels of cerebral blood flow and cerebral vasculitis. The net result is increased intracranial pressure (ICP) along with significant risk of brain tissue herniation and ischemic syndromes. ICP monitoring is critical in the ma ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  7. Nonintrusive Structure Blueprinting

    SBC: Physical Optics Corporation            Topic: SOCOM06006

    To address the SOCOM need for facility blueprinting of internal building structures, Physical Optics Corporation (POC) proposes to develop a new Nonintrusive Structure Blueprinting (NSB) technology. This proposed NSB system is based on active pulsation scanning of low-frequency energy to extract three-dimensional layouts of target structures and people behind multiple layers of various composites ...

    SBIR Phase I 2006 Department of DefenseSpecial Operations Command
  8. Non-Intrusive, Chemically-Specific Detection of Explosives

    SBC: SYAGEN TECHNOLOGY INC            Topic: N/A

    During the Phase I, a lightweight, multilayer coating will be deposited onto copper wire and the wire woven into a mesh. The coating provides a high level of EM shielding, including magnetic shielding, EMP shielding and powers line filtering. The woven mesh will form a flexible shield with similar properties. Draped over existing equipment or used to line the walls, it will provide temporary and ...

    SBIR Phase I 1998 Department of DefenseNational Geospatial-Intelligence Agency
  9. Night/Day-Enabled Miniature Emplaced Sensor and Infrared Surveillance System

    SBC: Physical Optics Corporation            Topic: SOCOM15006

    To address the USSOCOM need for Team Day/Night Motion Sensors, Physical Optics Corporation (POC) proposes to develop a new Night/Day-Enabled Miniature Emplaced Sensor and Infrared Surveillance (NEMESIS) system, based on the novel use of multi-aperture, compound-eye motion detectors to cue the capture of thermal surveillance imagery. Specifically, the innovation in the compound-eye optical design a ...

    SBIR Phase I 2015 Department of DefenseSpecial Operations Command
  10. Next Generation Integrated Electrophoretic Nanofluidic Biochip Sensor Platform for the THz Spectroscopic Finger Printing of Biological Species and Age

    SBC: REDONDO OPTICS, INC.            Topic: CBD10110

    Redondo Optics Inc. (ROI), a world leader in engineering and manufacturing of leading-edge nano-materials, optical sensors, fiber and integrated optics, and advanced photonics instrumentation proposes to develop and demonstrate an integrated electrophoretic nanofluidic biochip sensor platform for the accurate, reliable, and fast-throughput “label-less” THz spectroscopy finger printing of biolo ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
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