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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Novel Platform for Improving Access to and Efficacy of Fertility Treatments

    SBC: SeLux Diagnostics, Inc.            Topic: NICHD

    DESCRIPTION provided by applicant The goal of this SBIR proposal is to develop a novel technology that promises to confer pregnancy test like stability to immunoassays requiring signal amplification and precise quantification Aim focuses on developing multiplex ready assays for individual analytes from whole blood and demonstrating performance parity with clinical standards Aim translate ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a novel compression-based breast pump

    SBC: DS Labs            Topic: NICHD

    DESCRIPTION provided by applicant Although breast milk is undeniably the best nutrition for infants andlt of the million new mothers can keep up with the demands of pumping This is particularly challenging for working mothers who must rely on using a breast pump proven to be less efficient and effective than breastfeeding infants for of their work day to provide enough breast milk ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Flowable antimicrobial skin scaffolding matrix that promotes regeneration

    SBC: GEL4MED, INC.            Topic: 300

    DESCRIPTION provided by applicant The goal of this Phase I SBIR proposal is to test the feasibility of an antimicrobial tissue scaffolding hydrogel matrix in eliminating infecting bacteril pathogens and promoting wound regeneration Preventing and treating wound infections and regeneration are becoming less effective due to the rapid rise in Multi drug Resistant Organisms MDRO A recent study by Pad ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Small Molecule Treatments to Enhance Stroke Recovery

    SBC: Stemetix, Inc.            Topic: 102

    DESCRIPTION provided by applicant Stroke is a major public health problem in the U S and worldwide It is defined as an area of brain damage generally due to the sudden occlusion of an artery in or leading to the brain Stroke can cause weakness numbness visual disturbance speech difficulty balance problems and memory loss among other symptoms While good treatments exist to limit strok ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. High Speed Multi sensor Light Field Deconvolution Microscopy for Whole Brain Recording of Neuronal Activity

    SBC: Leaflabs, LLC            Topic: 101

    DESCRIPTION provided by applicant Recording all the neural activity in a D volume with millisecond timescale precision is a key goal of the BRAIN initiative Recently in a collaborative project with the Vaziri lab IMP Vienna we adapted the strategy of lightfield microscopy for D volumetric imaging of fluorescent neural calcium responses Prevedel This technology enables computatio ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Small Molecule Selective HDAC3 Inhibitors as a Novel Therapy for PTSD

    SBC: KDAc Therapeutics, Inc.            Topic: 101

    DESCRIPTION provided by applicant Post traumatic stress disorder PTSD is a major health problem affecting over million Americans every year Despite advances in behavioral treatment approaches e g prolonged exposure therapy PE a form of cognitive behavioral therapy CBT and the more recently adopted paradigm of combining PE CBT with medications to augment fear extinction learning t ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Low-Temperature Plasma Decontamination of Pharmaceutical Fill/Finish Operations

    SBC: PHYSICAL SCIENCES INC.            Topic: NCATS

    DESCRIPTION provided by applicant The goal of the proposed SBIR program is to develop an innovative atmospheric pressure microwave microplasma technology for the generation of charge neutral reactive oxygen and nitrogen species to replace vapor Phase hydrogen peroxide VPHP in parenteral drug manufacturing facilities including barrier isolator sterilization system and lyophilizers The propo ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. A NOVEL NEUROPROTECTIVE THERAPY FOR ALZHEIMER'S DISEASE

    SBC: Klogene Therapeutics, Inc.            Topic: NIA

    DESCRIPTION provided by applicant Alzheimerandapos s disease AD is one of the most significant public health problems of the st century with the number of patients in the US estimated to grow from million to million by and an annual cost of care projected to reach $ trillion Current treatments for AD have limited effect for a short duration and only serve to alleviate sympto ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Exploratory Chemistry on a new antibiotic

    SBC: NOVOBIOTIC PHARMACEUTICALS, LLC            Topic: NIAID

    This project studies the structure activity relationship SAR of the newly discovered antibiotic teixobactin with the goal of delivering a candidate that has development advantages over the parent compound Teixobactin is an unusual depsipeptide that is the first member of a novel class of peptidoglycan synthesis inhibitors Teixobactin targets lipid II peptidoglycan precursor and lipid III t ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Bactericidal antibiotic for Vancomycin Resistant Enterococci

    SBC: ARIETIS CORPORATION            Topic: NIAID

    DESCRIPTIONprovided by applicantThe goal of the project is to develop a therapeutic against vancomycin resistant enterococcusVREThese infections are a serious health concern because antibiotic resistance has gotten to the point where there are few or no effective treatment options availableFor the enterococciresistance is inherently linked to toleranceth ability of the pathogen to survive in the p ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
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