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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Clinical Translation of Near Infrared Nerve-Specific Fluorophores for Nerve-sparing Prostatectomy

    SBC: INHERENT TARGETING LLC            Topic: 102

    PROJECT SUMMARYIatrogenic nerve injury is one of the most feared complications of surgery. Nerves are critically important to the function of most tissues and nerve injury can lead to permanent disability. Surgery is performed commonly in the U.S. with approximately 40 million operations annually, incurring up to 600,000 iatrogenic nerve injuries. One procedure particularly plagued by nerve damage ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  2. Developing a novel, non-hormonal treatment paradigm for vaginal dryness in breast cancer survivors

    SBC: MADORRA INC.            Topic: 102

    Abstract The goal of this Fast-Track SBIR is to demonstrate the safety and efficacy of a therapeutic-ultrasound-based medical device to treat the symptoms of vaginal dryness for breast cancer survivors and postmenopausal women. Todayandapos;s best treatments for vaginal dryness all involve the use of hormones; yet, hormonal treatments are contraindicated for the 1.4 million breast cancer survivors ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  3. Optimization of an integrin enhancing molecule for the treatment of Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: OD

    Abstract Duchenne Muscular Dystrophy (DMD) is a fatal muscle disease with a predicted incidence of 1 in 5000 males. DMD results from mutations in the gene encoding dystrophin, a 427 kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and laminin in the extracellular matrix. The 7β1 integrin is a transmembrane linkage system in skeleta ...

    STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  4. Development and evaluation of a multi-media training program for elementary school bullying and abuse prevention: radKIDS 2.0

    SBC: OREGON RESEARCH BEHAVIORAL INTERVENTION STRATEGIES, INC.            Topic: 102

    AbstractChild victimization jeopardizes the healthy development of millions of American children every day. Minority, low income, and rural children are disproportionately exposed to more frequent, severe, and diverse forms of victimization (i.e., peer bullying, assault, physical and sexual abuse, property crime, neglect, and psychological maltreatment). Child victimization by peers is linked to p ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  5. Home biofeedback (VibroGait) for people with impaired somatosensation

    SBC: APDM, INC.            Topic: NIA

    Project Summary Impaired somatosensation or impaired use of somatosensation by the nervous system is one of the most common causes of balance and walking disability in older individuals. The human balance and gait control systems rely on somatosensory information from foot contact with the support surface during walking. Somatosensory loss is common with diabetes, normal aging, stroke, and with im ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  6. A User-Contextualized ROI Tool to Make Meaning of Lifetime Costs and Tradeoffs Associated with Different Degree Programs

    SBC: Vantage Point Consulting Inc.            Topic: 91990019R0016

    At the end of Phase II, the researchers will launch Return on College (ROC). Two versions of ROC will be developed. Using ROC-A, students will be able to search colleges nationwide based on geographic location and occupational goals with personalized output on projected debt, loan repayment, disposable income, graduation risk, and ROI the focal points of these decisions. Using ROC-B, prospective s ...

    SBIR Phase II 2020 Department of EducationInstitute of Education Sciences
  7. Real time optimization of electron-based fragmentation for middle and top-down proteomics in mass spectrometry

    SBC: E-Msion, Inc.            Topic: 400

    The identification and quantification of biological macromolecules remains challenging despite major advances in the speed, resolution and mass accuracy of modern mass spectrometers. A key weakness with current instrumentation lies in the methods used to induce fragmentation. The reliance in particular on collision-induced dissociation (CID) has limited such analyses to bottom-up workflows of tryp ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  8. Rapid, Point of Care Diagnostic for Malaria, highly sensitive for P. vivax, with species differentiation

    SBC: HEMEX HEALTH INC            Topic: NIAID

    Project Summary/Abstract While significant progress has been made in reducing malaria prevalence and deaths, malaria elimination remains an extremely difficult goal. P. falciparum and P. vivax species of malaria parasites account for ~95% of all human malaria infections. P. falciparum is more virulent and has a higher incidence of adverse clinical outcomes, but P. vivax is more pervasive and wides ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  9. Novel Test of Infant Hearing

    SBC: PERCEPTIVO, LLC            Topic: NIDCD

    PROJECT SUMMARY AND ABSTRACTHearing loss (HL) in the first two years of life can delay language development, making early diagnosis and intervention essential in the critical 3-18 mo period. Early identification of hearing loss has a significant impact on maintaining normal language development, leading to the 1-3-6 guidelines, which recommend that infants be screened by 1 mo, diagnosed by 3 mo, a ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  10. Advance Care Planning in the Dementias: Culturally-Tailored Caregiver Education for African Americans

    SBC: COLLINGE AND ASSOCIATES, INC.            Topic: N

    African Americans face significantly greater risk of Alzheimer’s Disease and other dementias than white Americans but receive disproportionately less attention to dementia screening and support, resulting in a silent epidemic in this underserved population. Advance Care Treatment Plan (ACT-Plan) is a culturally-tailored caregiver education program for African American dementia caregivers with de ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
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