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SBC: NATURAL PHARMACIA INTERNATIONAL, INC. Topic: NIAAA
DESCRIPTION provided by applicant This application for a Fast Track STTR award represents a collaboration between Natural Pharmacia International Inc NPI and McLean Hospital to initiate steps toward commercializing a isoflavone botanical product for treating alcoholism Excessive use of alcohol accounts for much of the public health burden related to alcohol use disorders including fetal a ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: BIOINVISION INC Topic: 102
Summary We will create a preclinical quantitative Cancer Imaging and Therapy Platform CITP which will allow one to study cancer biology and optimize pipelines of technologies imaging agents imaging methods targeted nano therapeutics tumor models etc especially for metastatic and invasive cancers Today primary tumor mass es are clinically controlled with surgical drug and radiatio ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: Epicypher, Inc. Topic: 103
PROJECT SUMMARY Nucleosomes are the basic building blocks of chromatin and composed of bp DNA wrapped around a core histone octamer Chromatin function is controlled by the dynamic addition removal of histone post translational modifications PTMs Significantly alterations in specific PTMs are associated with changes in gene expression driving the emergence progression of many cancer ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: Digital Health Empowerment, Inc Topic: NIDA
DESCRIPTION provided by applicant Because many people who inject drugs PWID do not receive adequate information about HIV or HCV testing and prevention or overdose prevention and response training we propose to develop a Mobile Intervention Kit to deliver technology based interventions from a library of theory guided video content The first iteration will address overdose prevention and r ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: 1ST PLAYABLE PRODUCTIONS LLC Topic: NIA
DESCRIPTION provided by applicant st Playable Productions and Union College propose to develop a commercializable product combining physical exercise and cognitive activities through interactive gaming on a stationary bicycle to help prevent cognitive decline and dementia in older adults The Interactive Physical and Cognitive Exercise System iPACES developed by Union Collegeandapos s Health ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: ImageIQ, Inc. Topic: 300
DESCRIPTION provided by applicant Chronic viral hepatitis is clinically silent until development of cirrhosis and hepatic decompensation Decompensated cirrhosis is a precursor to liver failure and is associated with increased risk of severe esophageal bleeding significant cardiovascular events and death The gold standard for diagnosing cirrhosis is liver biopsy though problems with the pro ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: Oncotab, Inc. Topic: NCI
DESCRIPTION provided by applicant Pancreatic cancer has the worst prognosis of all cancers and is the fourth leading cause of cancer related deaths in the United States Patients usually present with advanced disease making curative attempts difficult Surgery is the only curative therapy since radiotherapy and chemotherapy remain largely ineffective coupled with undesirable side effects Desp ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: TDA RESEARCH, INC. Topic: NIAID
Project Summary Abstract Development of Optimized Endectocide treated Bird Feed Formulations for West Nile Virus Control STTR Phase I Application PIs Brady Clapsaddle TDA Research Inc Dr Brian Foy Colorado State University West Nile Virus WNV is the leading cause of domestically acquired arboviral disease in the United States resulting in significant disease and death every year in both ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: Simpore Inc. Topic: 400
DESCRIPTION provided by applicant The global market for nanoparticles NP in biotechnology drug development and drug delivery was estimated to be $ B for and is expected to reach more than $ B by The two most active areas of product development are NPs for drug delivery and for in vivo imaging In these applications it is often critical that he outer surfaces of NPs are functiona ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: DESIGNMEDIX, INC. Topic: R
DESCRIPTION provided by applicant Trichomonas vaginalis is the causative agent of the most common non viral sexually transmitted infection with million new cases reported annually in the world and million cases in the U S In addition to infections of the urogenital tract trichomoniasis increases the risk of adverse pregnancy outcomes and HIV transmission and increases the incidence ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health